J
José Luis Ambite
Researcher at University of Southern California
Publications - 164
Citations - 5801
José Luis Ambite is an academic researcher from University of Southern California. The author has contributed to research in topics: Population & Genome-wide association study. The author has an hindex of 38, co-authored 152 publications receiving 5020 citations. Previous affiliations of José Luis Ambite include Information Sciences Institute & Georgia State University.
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Book ChapterDOI
Leveraging Linked Data to Discover Semantic Relations Within Data Sources
TL;DR: This work presents a novel approach to automatically discover the semantic relations within a given data source by mining the small graph patterns occurring in Linked Open Data and combining them to build a graph that will be used to infer semantic relations.
Journal ArticleDOI
Genetics of Chronic Kidney Disease Stages Across Ancestries: The PAGE Study.
Bridget M Lin,Girish N. Nadkarni,Ran Tao,Mariaelisa Graff,Myriam Fornage,Steven Buyske,Tara C. Matise,Heather M. Highland,Lynne R. Wilkens,Christopher S. Carlson,Christopher S. Carlson,S. Lani Park,V. Wendy Setiawan,José Luis Ambite,Gerardo Heiss,Eric Boerwinkle,Danyu Lin,Andrew P. Morris,Andrew P. Morris,Ruth J. F. Loos,Charles Kooperberg,Kari E. North,Christina L. Wassel,Nora Franceschini +23 more
TL;DR: The authors' genetic study identified a novel association at NMT2 for CKD and showed for the first time strong associations of the APOL1 variants with ESKD across multi-ethnic populations.
Journal ArticleDOI
Genetic variants associated with fasting glucose and insulin concentrations in an ethnically diverse population: results from the Population Architecture using Genomics and Epidemiology (PAGE) study
Megan D. Fesinmeyer,James B. Meigs,Kari E. North,Fredrick R. Schumacher,Petra Bůžková,Nora Franceschini,Jeff Haessler,Robert Goodloe,Kylee L. Spencer,Venkata Saroja Voruganti,Barbara V. Howard,Rebecca D. Jackson,Laurence N. Kolonel,Simin Liu,JoAnn E. Manson,Kristine R. Monroe,Kenneth J. Mukamal,Holli H. Dilks,Sarah A. Pendergrass,Andrew Nato,Peggy Wan,Lynne R. Wilkens,Loic Le Marchand,José Luis Ambite,Steven Buyske,Jose C. Florez,Dana C. Crawford,Lucia A. Hindorff,Christopher A. Haiman,Ulrike Peters,James S. Pankow +30 more
TL;DR: Generalization of results across multiple racial/ethnic groups helps confirm the relevance of some of these loci for glucose and insulin metabolism, and Lack of association in non-EA groups may be due to insufficient power, or to unique patterns of linkage disequilibrium.
Journal ArticleDOI
The genetic underpinnings of variation in ages at menarche and natural menopause among women from the multi-ethnic Population Architecture using Genomics and Epidemiology (PAGE) Study: A trans-ethnic meta-analysis.
Lindsay Fernández-Rhodes,Jennifer Malinowski,Yujie Wang,Ran Tao,Nathan Pankratz,Janina M. Jeff,Sachiko Yoneyama,Cara L. Carty,V. Wendy Setiawan,Loic Le Marchand,Christopher A. Haiman,Steven Corbett,Ellen W. Demerath,Gerardo Heiss,Myron D. Gross,Petra Buzkova,Dana C. Crawford,Steven C. Hunt,Dabeeru C. Rao,Karen Schwander,Aravinda Chakravarti,Omri Gottesman,Noura S. Abul-Husn,Erwin P. Bottinger,Ruth J. F. Loos,Leslie J. Raffel,Jie Yao,Xiuqing Guo,Suzette J. Bielinski,Jerome I. Rotter,Dhananjay Vaidya,Yii-Der Ida Chen,Sheila F. Castañeda,Martha L. Daviglus,Robert C. Kaplan,Gregory A. Talavera,Kelli K. Ryckman,Ulrike Peters,José Luis Ambite,Steven Buyske,Lucia A. Hindorff,Charles Kooperberg,Tara C. Matise,Nora Franceschini,Kari E. North +44 more
TL;DR: The findings support the transferability of reproductive trait loci discovered in European women to women of other race/ethnicities and indicate the presence of additional trans-ethnic associations both at both novel and established loci.
Journal ArticleDOI
Multiancestral Analysis of Inflammation-Related Genetic Variants and C-Reactive Protein in the Population Architecture Using Genomics and Epidemiology Study
Jonathan M. Kocarnik,Sarah A. Pendergrass,Cara L. Carty,James S. Pankow,Fredrick R. Schumacher,Iona Cheng,Peter Durda,José Luis Ambite,Ewa Deelman,Nancy R. Cook,Simin Liu,Jean Wactawski-Wende,Carolyn M. Hutter,Kristin Brown-Gentry,Sarah Wilson,Lyle G. Best,Nathan Pankratz,Ching-Ping Hong,Shelley A. Cole,V. Saroja Voruganti,Petra Bůžková,Neal W. Jorgensen,Nancy S. Jenny,Lynne R. Wilkens,Christopher A. Haiman,Laurence N. Kolonel,Andrea Z. LaCroix,Kari E. North,Rebecca D. Jackson,Loic Le Marchand,Lucia A. Hindorff,Dana C. Crawford,Myron D. Gross,Ulrike Peters +33 more
TL;DR: The findings demonstrate the benefit of evaluating genotype–phenotype associations in multiple race/ethnicity groups and looking for pleiotropic relationships among SNPs previously associated with related phenotypes.