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Karen Schwander

Researcher at Washington University in St. Louis

Publications -  69
Citations -  3040

Karen Schwander is an academic researcher from Washington University in St. Louis. The author has contributed to research in topics: Genome-wide association study & Population. The author has an hindex of 22, co-authored 60 publications receiving 2584 citations. Previous affiliations of Karen Schwander include University of Washington.

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Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries

Mary F. Feitosa, +299 more
- 18 Jun 2018 - 
TL;DR: In insights into the role of alcohol consumption in the genetic architecture of hypertension, a large two-stage investigation incorporating joint testing of main genetic effects and single nucleotide variant (SNV)-alcohol consumption interactions is conducted.
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Single-trait and multi-trait genome-wide association analyses identify novel loci for blood pressure in African-ancestry populations

Jingjing Liang, +81 more
- 12 May 2017 - 
TL;DR: This study provides new evidence for genes related to hypertension susceptibility, and the need to study African-ancestry populations in order to identify biologic factors contributing to hypertension.
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A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure

Yun J. Sung, +329 more
TL;DR: The identified loci show strong evidence for regulatory features and support shared pathophysiology with cardiometabolic and addiction traits and highlight a role in BP regulation for biological candidates such as modulators of vascular structure and function.
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Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions

Paul S. de Vries, +293 more
TL;DR: In this paper, gene-alcohol interactions were incorporated into a multiancestry genome-wide association study of levels of high-density lipoprotein cholesterol, low-density cholesterol, and triglycerides.
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A genome-wide scan for urinary albumin excretion in hypertensive families.

TL;DR: These analyses demonstrate the marked heritability of urine ACR in families enriched for the presence of members with essential hypertension and suggest that a gene(s) associated with urinary ACR may be present on human chromosomes 19 and 12.