J
Jennifer Malinowski
Researcher at Vanderbilt University
Publications - 27
Citations - 777
Jennifer Malinowski is an academic researcher from Vanderbilt University. The author has contributed to research in topics: Population & Medicine. The author has an hindex of 12, co-authored 19 publications receiving 526 citations. Previous affiliations of Jennifer Malinowski include Yale University & Icahn School of Medicine at Mount Sinai.
Papers
More filters
Journal ArticleDOI
Meta-Analysis of Genome-Wide Association Studies for Abdominal Aortic Aneurysm Identifies Four New Disease-Specific Risk Loci
Gregory T. Jones,Gerard Tromp,Helena Kuivaniemi,Solveig Gretarsdottir,Annette F. Baas,Betti Giusti,Ewa Strauss,Femke N G van 't Hof,Tom R. Webb,Robert Erdman,Marylyn D. Ritchie,James R. Elmore,Anurag Verma,Sarah A. Pendergrass,Iftikhar J. Kullo,Zi Ye,Peggy L. Peissig,Omri Gottesman,Omri Gottesman,Shefali S. Verma,Jennifer Malinowski,Laura J. Rasmussen-Torvik,Kenneth M. Borthwick,Diane T. Smelser,David R. Crosslin,Mariza de Andrade,Evan J. Ryer,Catherine A. McCarty,E.P. Bottinger,Jennifer A. Pacheco,Dana C. Crawford,David Carrell,Glenn S. Gerhard,David P. Franklin,David J. Carey,Victoria L Phillips,Michael J.A. Williams,Wenhua Wei,Ross D. Blair,Andrew Hill,Thodor M. Vasudevan,David R. Lewis,Ian Thomson,J Krysa,Geraldine B. Hill,Justin A. Roake,Tony R. Merriman,Grzegorz Oszkinis,Silvia Galora,Claudia Saracini,Rosanna Abbate,Rosanna Abbate,Raffaele Pulli,Carlo Pratesi,Athanasios Saratzis,Ana Raquel Verissimo,Suzannah Bumpstead,Stephen A. Badger,Rachel E. Clough,Gillian Cockerill,Hany Hafez,D. Julian A. Scott,T. Simon Futers,Simon P. R. Romaine,Katherine I Bridge,Kathryn J. Griffin,Marc A. Bailey,Alberto Smith,Matthew M. Thompson,Frank M. van Bockxmeer,Stefan E Matthiasson,Gudmar Thorleifsson,Gudmar Thorleifsson,Unnur Thorsteinsdottir,Jan D. Blankensteijn,Joep A.W. Teijink,Joep A.W. Teijink,Cisca Wijmenga,Jacqueline de Graaf,Lambertus A. Kiemeney,Jes S. Lindholt,Anne Hughes,Declan Bradley,Kathleen Stirrups,Jonathan Golledge,Paul Norman,Janet T. Powell,Steve E. Humphries,Stephen E. Hamby,Alison H. Goodall,Christopher P. Nelson,Natzi Sakalihasan,Audrey Courtois,Robert E. Ferrell,Per Eriksson,Lasse Folkersen,Anders Franco-Cereceda,John D. Eicher,Andrew D. Johnson,Christer Betsholtz,Arno Ruusalepp,Arno Ruusalepp,Oscar Franzén,Oscar Franzén,Eric E. Schadt,Johan Björkegren,Leonard Lipovich,Leonard Lipovich,Anne M. Drolet,Eric L. G. Verhoeven,Clark J. Zeebregts,Robert H. Geelkerken,Marc R.H.M. van Sambeek,Steven M.M. van Sterkenburg,Jean-Paul P.M. de Vries,K. Stefansson,John R. Thompson,Paul I.W. de Bakker,Panos Deloukas,Robert D. Sayers,Seamus C. Harrison,Andre M. van Rij,Nilesh J. Samani,Matthew J. Bown +123 more
TL;DR: The 4 new risk loci for AAA seem to be specific for AAA compared with other cardiovascular diseases and related traits suggesting that traditional cardiovascular risk factor management may only have limited value in preventing the progression of aneurysmal disease.
Journal ArticleDOI
Cardiometabolic effects of genetic upregulation of the interleukin 1 receptor antagonist: A Mendelian randomisation analysis
Daniel F. Freitag,Adam S. Butterworth,Peter Willeit,Joanna M. M. Howson,Stephen Burgess,Stephen Kaptoge,Robin Young,Weang Kee Ho,Angela M. Wood,Michael J. Sweeting,Sarah Spackman,James R Staley,Anna Ramond,Eric L. Harshfield,Sune F. Nielsen,Peer Grande,Leslie A. Lange,Matthew J. Bown,Gregory T. Jones,Robert A. Scott,Steve Bevan,Eleonora Porcu,Gudmar Thorleifsson,Lingyao Zeng,Thorsten Kessler,Majid Nikpay,Ron Do,Weihua Zhang,Jemma C. Hopewell,Marcus E. Kleber,Graciela E. Delgado,Christopher P. Nelson,Anuj Goel,Joshua C. Bis,Abbas Dehghan,Symen Ligthart,Albert V. Smith,Liming Qu,Liming Qu,Femke N G van 't Hof,Paul I.W. de Bakker,Annette F. Baas,Andre M. van Rij,Gerard Tromp,Helena Kuivaniemi,Marylyn D. Ritchie,Shefali S. Verma,Dana C. Crawford,Jennifer Malinowski,Mariza de Andrade,Iftikhar J. Kullo,Peggy L. Peissig,Catherine A. McCarty,Erwin P. Bottinger,Omri Gottesman,David R. Crosslin,David Carrell,Laura J. Rasmussen-Torvik,Jennifer A. Pacheco,Jie Huang,Nicholas J. Timpson,Johannes Kettunen,Johannes Kettunen,Mika Ala-Korpela,Mika Ala-Korpela,Gary F. Mitchell,Afshin Parsa,Ian B. Wilkinson,Mathias Gorski,Yong Li,Nora Franceschini,Margaux F. Keller,Santhi K. Ganesh,Carl D. Langefeld,Lucie Bruijn,Matthew A. Brown,David M. Evans,Svetlana Baltic,Manuel A. R. Ferreira,Hansjörg Baurecht,Stephan Weidinger,Andre Franke,Steven A. Lubitz,Martina Müller-Nurasyid,Janine F. Felix,Janine F. Felix,Nicholas L. Smith,Marc Sudman,Susan D. Thompson,Eleftheria Zeggini,Kalliope Panoutsopoulou,Mike A. Nalls,Andrew B. Singleton,Constantin Polychronakos,Jonathan P. Bradfield,Hakon Hakonarson,Douglas F. Easton,Deborah J. Thompson,Ian Tomlinson,Malcolm G. Dunlop,Kari Hemminki,Gareth J. Morgan,Gareth J. Morgan,Timothy Eisen,Hartmut Goldschmidt,James M. Allan,Marc Henrion,Nicola Whiffin,Yufei Wang,Daniel Chubb,Mark M. Iles,D. Timothy Bishop,Matthew Law,Nicholas K. Hayward,Yang Luo,Sergey Nejentsev,Maja Barbalić,David C. Crossman,Serena Sanna,Nicole Soranzo,Hugh S. Markus,Nicholas J. Wareham,Daniel J. Rader,Muredach P. Reilly,Themistocles L. Assimes,Tamara B. Harris,Albert Hofman,Oscar H. Franco,Vilmundur Gudnason,Russell P. Tracy,Russell P. Tracy,Bruce M. Psaty,Martin Farrall,Hugh Watkins,Alistair S. Hall,Nilesh J. Samani,Winfried März,Robert Clarke,Rory Collins,Jaspal S. Kooner,John C. Chambers,Sekar Kathiresan,Ruth McPherson,Jeanette Erdmann,Adnan Kastrati,Heribert Schunkert,Kari Stefansson,Unnur Thorsteinsdottir,Jeremy D. Walston,Anne Tybjærg-Hansen,Dewan S. Alam,Abdullah Al Shafi Majumder,Emanuele Di Angelantonio,Rajiv Chowdhury,Børge G. Nordestgaard,Danish Saleheen,Simon G. Thompson,John Danesh,Richard S. Houlston +158 more
TL;DR: In this paper, a genetic score combining the effects of alleles of two common variants (rs6743376 and rs1542176) that are located upstream of IL1RN, the gene encoding the IL-1 receptor antagonist (IL-1Ra; an endogenous inhibitor of both IL 1 alpha and IL 1 beta) was created to investigate potential cardiovascular and other effects of long-term pharmacological interleukin 1 inhibition.
Journal ArticleDOI
Replication of genetic loci for ages at menarche and menopause in the multi-ethnic Population Architecture using Genomics and Epidemiology (PAGE) study
Cara L. Carty,Kylee L. Spencer,Veronica Wendy Setiawan,Lindsay Fernández-Rhodes,Jennifer Malinowski,Steven Buyske,Alicia Young,Neal W. Jorgensen,Iona Cheng,Christopher S. Carlson,Kristin Brown-Gentry,Robert Goodloe,Amy J. Park,Nisha I. Parikh,B. E. Henderson,Loic Le Marchand,Jean Wactawski-Wende,Myriam Fornage,Tara C. Matise,Lucia A. Hindorff,Alice M. Arnold,Christopher A. Haiman,Nora Franceschini,Ulrike Peters,Dana C. Crawford +24 more
TL;DR: Most, but not all reported SNPs in European descent populations are replicated and the epidemiologic architecture of these early reported variants is examined, describing their generalizability and effect size across differing ancestral populations.
Journal ArticleDOI
Shared Genetic Risk Factors of Intracranial, Abdominal, and Thoracic Aneurysms.
Femke N G van 't Hof,Ynte M. Ruigrok,Cue Hyunkyu Lee,Stephan Ripke,Graig Anderson,Mariza de Andrade,Annette F. Baas,Jan D. Blankensteijn,Erwin P. Bottinger,Matthew J. Bown,Joseph P. Broderick,Philippe Bijlenga,David Carrell,Dana C. Crawford,David R. Crosslin,Christian Ebeling,Johan G. Eriksson,Myriam Fornage,Tatiana Foroud,Mikael von und zu Fraunberg,Christoph M. Friedrich,Emilia I. Gaal,Omri Gottesman,Dongchuan Guo,Seamus C. Harrison,Juha Hernesniemi,Albert Hofman,Ituro Inoue,Juha E. Jääskeläinen,Gregory T. Jones,Lambertus A. Kiemeney,Riku Kivisaari,Nerissa U. Ko,Seppo Koskinen,Michiaki Kubo,Iftikhar J. Kullo,Helena Kuivaniemi,Mitja I. Kurki,Aki Laakso,Dongbing Lai,Suzanne M. Leal,Hanna Lehto,Scott A. LeMaire,Siew-Kee Low,Jennifer Malinowski,Catherine A. McCarty,Dianna M. Milewicz,Thomas H. Mosley,Yusuke Nakamura,Hirofumi Nakaoka,Mika Niemelä,Jennifer A. Pacheco,Peggy L. Peissig,Joanna Pera,Laura J. Rasmussen-Torvik,Marylyn D. Ritchie,Fernando Rivadeneira,Andre M. van Rij,Regie Lyn P. Santos-Cortez,Athanasios Saratzis,Agnieszka Slowik,Atsushi Takahashi,Gerard Tromp,André G. Uitterlinden,Shefali S. Verma,Sita H. Vermeulen,Gao Wang,Buhm Han,Gabriel J.E. Rinkel,Paul I.W. de Bakker +69 more
TL;DR: Although there was no evidence for polygenic overlap between IAs, AAAs, and TAAs, a mega‐analysis of 1000 Genomes Project‐imputed genome‐wide association study (GWAS) data found nominally significant effects of two established risk loci for IAs andTAAs in AAAs.
Journal ArticleDOI
Genetic Variation and Reproductive Timing: African American Women from the Population Architecture Using Genomics and Epidemiology (PAGE) Study
Kylee L. Spencer,Jennifer Malinowski,Cara L. Carty,Nora Franceschini,Lindsay Fernández-Rhodes,Alicia Young,Iona Cheng,Marylyn D. Ritchie,Marylyn D. Ritchie,Christopher A. Haiman,Lynne R. Wilkens,ChunyuanWu,Tara C. Matise,Christopher S. Carlson,Kathleen Brennan,Amy J. Park,Aleksandar Rajkovic,Lucia A. Hindorff,Steven Buyske,Dana C. Crawford +19 more
TL;DR: While most associations were identified in either AM or ANM, the lack of generalization coupled with the potentially novel associations identified here emphasize the need for additional genetic discovery efforts for AM and ANM in diverse populations.