Joseph G. Joyce

TL;DR: The replication-defective adenovirus is a promising vaccine vector for development of an HIV-1 vaccine and elicited by a replication-incompetent Ad5 vector, used either alone or as a booster inoculation after priming with a DNA vector.

TL;DR: It is established for the first time that the carboxyl-terminal portion of HPV L1 interacts with heparin, and that this region appears to be crucial for interaction with the cell surface.

TL;DR: Systematic evaluation of M2 peptide conjugate vaccines in mice, ferrets, and rhesus monkeys revealed protection against lethal challenge of either H1N1 or H3N1 virus in mice and the ability to reduce viral shedding in the lower respiratory tracts of mice and ferrets.

TL;DR: The chemical structure of PS/A is determined to be β(1-6)-N-acetylglucosamine (PNAG), which helps to differentiate it from PIA on the basis of immunogenicity, molecular size, and solubility.

TL;DR: IsdB has excellent prospects for use as a vaccine against S. aureus disease in humans and was highly immunogenic in mice when it was formulated with amorphous aluminum hydroxyphosphate sulfate adjuvant, and the resulting antibody responses were associated with reproducible and significant protection in animal models of infection.