J
Joseph K. Ng’ang’a
Researcher at Jomo Kenyatta University of Agriculture and Technology
Publications - 20
Citations - 154
Joseph K. Ng’ang’a is an academic researcher from Jomo Kenyatta University of Agriculture and Technology. The author has contributed to research in topics: Plasmodium berghei & Artemisinin. The author has an hindex of 6, co-authored 20 publications receiving 101 citations. Previous affiliations of Joseph K. Ng’ang’a include International Livestock Research Institute & Pan-African University.
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Plasmodium berghei ANKA: selection of resistance to piperaquine and lumefantrine in a mouse model.
Daniel Kiboi,Beatrice Irungu,Bernard Langat,Sergio Wittlin,Reto Brun,Jacques Chollet,Oyindamola O. Abiodun,Joseph K. Ng’ang’a,V.C.S. Nyambati,G.M. Rukunga,A. Bell,Alexis Nzila,Alexis Nzila +12 more
TL;DR: Cross-resistance studies showed that the PQ- resistant line was highly resistant to LM, while the LM-resistant line remained sensitive to PQ, so if the mechanism of resistance is similar in P. berghei and Plasmodium falciparum, the use of LM should not select for PQ resistance.
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Selected ethno-medicinal plants from Kenya with in vitro activity against major African livestock pathogens belonging to the "Mycoplasma mycoides cluster".
Francisca Kama-Kama,Francisca Kama-Kama,Jacob O. Midiwo,Joseph K. Ng’ang’a,Naomi Maina,Elise Schiek,Leonidah Kerubo Omosa,George O Osanjo,Jan Naessens +8 more
TL;DR: Identifying plants that exhibit antimycoplasmal activities using an ethnobotanical approach suggested that these plants could potentially contain antimicrobial compounds that might be useful for the treatment of respiratory diseases in ruminants.
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Comparison of phytochemical profiles and antimalarial activities of Artemisia afra plant collected from five countries in Africa
TL;DR: The extracts from Burundi had the highest total content of phenols and flavonoids and also the highest level of antimalarial activity compared to the other plant extracts.
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Selective sweeps and genetic lineages of Plasmodium falciparum multi-drug resistance ( pfmdr1 ) gene in Kenya
Peninah Muiruri,Peninah Muiruri,Denis W. Juma,Luicer A. Ingasia,Lorna J. Chebon,Benjamin Opot,Bidii S. Ngalah,Jelagat Cheruiyot,Ben Andagalu,Hoseah M. Akala,Venny C. S. Nyambati,Joseph K. Ng’ang’a,Edwin Kamau,Edwin Kamau +13 more
TL;DR: Evidence of selective sweep and genetic lineages in pfmdr1 genotypes associated with the use of artemether–lumefantrine, as the first-line treatment in Kenya are investigated to show effective malaria control policies should be based on the region and not at a country wide level.
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High resolution mapping of trypanosomosis resistance loci Tir2 and Tir3 using F12 advanced intercross lines with major locus Tir1 fixed for the susceptible allele.
TL;DR: The mapped QTL regions encompass genes that are vital to innate immune response and can be potential candidate genes for the underlying QTL.