J
Julijana Ivanisevic
Researcher at University of Lausanne
Publications - 77
Citations - 5895
Julijana Ivanisevic is an academic researcher from University of Lausanne. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 29, co-authored 61 publications receiving 3725 citations. Previous affiliations of Julijana Ivanisevic include Scripps Research Institute & Aix-Marseille University.
Papers
More filters
Journal ArticleDOI
Metabolomics: beyond biomarkers and towards mechanisms
TL;DR: Because of the inherent sensitivity of metabolomics, subtle alterations in biological pathways can be detected to provide insight into the mechanisms that underlie various physiological conditions and aberrant processes, including diseases.
Journal ArticleDOI
α-ketoglutarate orchestrates macrophage activation through metabolic and epigenetic reprogramming
Pu-Ste Liu,Haiping Wang,Xiaoyun Li,Tung Chao,Tony Teav,Stefan Christen,Stefan Christen,Giusy Di Conza,Wan-Chen Cheng,Chih Hung Chou,Magdalena Vavakova,Charlotte Muret,Koen Debackere,Koen Debackere,Massimiliano Mazzone,Massimiliano Mazzone,Hsien Da Huang,Sarah-Maria Fendt,Sarah-Maria Fendt,Julijana Ivanisevic,Ping-Chih Ho +20 more
TL;DR: New mechanistic regulations by which glutamine metabolism tailors the immune responses of macrophages through metabolic and epigenetic reprogramming are revealed.
Journal ArticleDOI
Identification of bioactive metabolites using activity metabolomics
TL;DR: This Review focuses on recent progress in using metabolomics to understand how the metabolome influences other omics and, by extension, to reveal the active role of metabolites in physiology and disease.
Journal ArticleDOI
Interactive XCMS Online: simplifying advanced metabolomic data processing and subsequent statistical analyses.
Harsha Gowda,Julijana Ivanisevic,Caroline H. Johnson,Michael E. Kurczy,H. Paul Benton,Duane Rinehart,Thomas Nguyen,Jayashree Ray,Jennifer V. Kuehl,Bernardo Arevalo,Peter D. Westenskow,Junhua Wang,Adam P. Arkin,Adam M. Deutschbauer,Gary J. Patti,Gary Siuzdak +15 more
TL;DR: An enhanced XCMS Online interface is introduced that enables users to perform dependent (paired) two-group comparisons, meta-analysis, and multigroup comparisons, with comprehensive statistical output and interactive visualization tools.
Journal ArticleDOI
De novo NAD + synthesis enhances mitochondrial function and improves health
Elena Katsyuba,Adrienne Mottis,Marika Zietak,Marika Zietak,Francesca De Franco,Vera van der Velpen,Karim Gariani,Karim Gariani,Dongryeol Ryu,Dongryeol Ryu,Lucia Cialabrini,Olli Matilainen,Olli Matilainen,Paride Liscio,Nicola Giacchè,Nadine Stokar-Regenscheit,Nadine Stokar-Regenscheit,David Legouis,Sophie de Seigneux,Julijana Ivanisevic,Nadia Raffaelli,Kristina Schoonjans,Roberto Pellicciari,Johan Auwerx +23 more
TL;DR: Genetic or pharmacological inhibition of α-amino-β-carboxymuconate-ε-semialdehyde decarboxylase increases NAD+ and improves mitochondrial function in nematodes and mice, and may have therapeutic potential in kidney and liver disease.