K
K. N. Houk
Researcher at University of California, Los Angeles
Publications - 544
Citations - 19761
K. N. Houk is an academic researcher from University of California, Los Angeles. The author has contributed to research in topics: Catalysis & Chemistry. The author has an hindex of 68, co-authored 478 publications receiving 17032 citations. Previous affiliations of K. N. Houk include University of Pittsburgh & Leibniz University of Hanover.
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Journal ArticleDOI
High-Rate Accelerations in Oxy-Cope Rearrangements Induced by Sulfur Substitution: Kinetic Study Involving Electronically and Geometrically Differentiated 1-Alkenyl-2-(Z-1-propenyl)-7,7-dimethyl-exo-norbornan-2-ols
TL;DR: In this article, the rates of anionically promoted oxy-Cope rearrangement of five structurally related exo-norbornanols have been determined, and it is shown that the presence of the PhS substituent causes rearrangements to occur approximately 103 times faster by lowering the activation energy to the extent of 3−4 kcal/mol.
Journal ArticleDOI
Attenuating and Supplanting Nonclassical Stabilization: Cr(CO)3-Complexed Benzonorbornenyl Cations
Journal ArticleDOI
Tuning exo/endo stereoselectivity in ene reactions
Bert E. Thomas,K. N. Houk +1 more
Journal ArticleDOI
Gold-catalyzed, intramolecular, oxygen-transfer reactions of 2-alkynyl-1,5-diketones or 2-alkynyl-5-ketoesters: scope, expansion, and mechanistic investigations on a new [4+2] cycloaddition.
TL;DR: The results from both, the designed isotopic experiments and theoretical calculations, satisfactorily supported the novel proposed intramolecular [4+2] cycloaddition of a gold-containing furanium intermediate to a carbonyl group, instead of the previous well-accepted [2+1] pathway.
Journal ArticleDOI
Readily Accessible Ambiphilic Cyclopentadienes for Bioorthogonal Labeling
TL;DR: A new class of bioorthogonal reagents based on the cyclopentadiene scaffold is described, allowing for tandem labeling studies with mutually orthogonal azides that react rapidly with DIBAC.