K
K. N. Houk
Researcher at University of California, Los Angeles
Publications - 544
Citations - 19761
K. N. Houk is an academic researcher from University of California, Los Angeles. The author has contributed to research in topics: Catalysis & Chemistry. The author has an hindex of 68, co-authored 478 publications receiving 17032 citations. Previous affiliations of K. N. Houk include University of Pittsburgh & Leibniz University of Hanover.
Papers
More filters
Journal ArticleDOI
Stereoselective synthesis of the tetracyclic core of manzamine via the vinylogous amide photocycloaddition cascade
Jeffrey D. Winkler,Jeffrey M. Axten,Abdel Hakim Hammach,Young-Shin Kwak,Urs Lengweiler,Melissa J. Lucero,K. N. Houk +6 more
TL;DR: In this article, the stereoselective preparation of the tetracyclic core of the manzamine alkaloids via the intramolecular vinylogous amide photocycloaddition/retro-Mannich fragmentation/mannich closure cascade is described.
Journal ArticleDOI
Quantification of Solvent Effects on the Acidities of Z and E Esters from Fluid Simulations
Journal ArticleDOI
Chemical study on hapalosin, a cyclic depsipeptide possessing multidrug resistance reversing activities : synthesis, structure and biological activity
Toshiaki Okuno,Ken Ohmori,Shigeru Nishiyama,Shosuke Yamamura,Kensuke Nakamura,K. N. Houk,Kazuya Okamoto +6 more
TL;DR: In this article, a multidrug resistance reversing activity was demonstrated in the N-demethylhapalosin (N-DEMethyl-Hapalosin 11) using a spectroscopic manner and molecular modeling studies.
Journal ArticleDOI
Isotope effects for Lewis acid catalyzed Diels-Alder reactions. The experimental transition state
TL;DR: In this paper, the isotope effects for all positions on isoprene in its reactions with methyl vinyl ketone, ethyl acrylate, and acrolein catalyzed by Et 2 AlCl were determined.
Journal ArticleDOI
Isomeric triazines exhibit unique profiles of bioorthogonal reactivity
David N Kamber,Sean S Nguyen,Fang Liu,Fang Liu,Jeffrey S Briggs,Hui-Wen Shih,R. David Row,Zane G Long,K. N. Houk,Yong Liang,Jennifer A. Prescher +10 more
TL;DR: Isomeric triazines can be tuned to exhibit unique reaction profiles with biocompatible strained alkenes and alkynes.