K
K. N. Houk
Researcher at University of California, Los Angeles
Publications - 544
Citations - 19761
K. N. Houk is an academic researcher from University of California, Los Angeles. The author has contributed to research in topics: Catalysis & Chemistry. The author has an hindex of 68, co-authored 478 publications receiving 17032 citations. Previous affiliations of K. N. Houk include University of Pittsburgh & Leibniz University of Hanover.
Papers
More filters
Journal ArticleDOI
Ab Initio-Based Force Field Modeling of the Transition States And Stereoselectivities of Lewis Acid-Catalyzed Asymmetric Diels-Alder Reactions
Journal ArticleDOI
Transition States of Vicinal Diamine-Catalyzed Aldol Reactions
TL;DR: The transition states of aldol reactions catalyzed by vicinal diamines are characterized with density functional calculations and it is found that a cyclic transition state involving a nine-membered hydrogen-bonded ring is preferred.
Journal ArticleDOI
Mechanistic Variations and Rate Effects of Alkoxy and Thioalkoxy Substituents on Anionic Oxy-Cope Rearrangements
TL;DR: In this paper, the effects of thiomethoxy and methoxy substituents on the rates and the mechanisms of anionic oxy-Cope rearrangements were investigated with density functional theory (B3LYP/6-31+G*).
Journal ArticleDOI
π-Facial Diastereoselection in Diels−Alder Reactions of (R)-4-[(p-Tolylsulfinyl)methyl]quinols
TL;DR: In this article, the transition state energies for cycloadditions with cyclopentadiene were derived at the RHF/6-31G* theory level, in full agreement with the experimental results.
Journal ArticleDOI
Sungeidines from a Non-canonical Enediyne Biosynthetic Pathway.
Zhen Jie Low,Guang-Lei Ma,Hoa Thi Tran,Yike Zou,Juan Xiong,Juan Xiong,Limei Pang,Selbi Nuryyeva,Hong Ye,Jin-Feng Hu,K. N. Houk,Zhao-Xun Liang +11 more
TL;DR: The genome-guided discovery of sungeidines is reported and it is proposed that the loss of genes, including a putative epoxidase gene, causes the divergence of the sungeidine pathway from other canonical enediyne pathways.