K
Kamalvishnu P. Gottimukkala
Researcher at International Centre for Genetic Engineering and Biotechnology
Publications - 18
Citations - 867
Kamalvishnu P. Gottimukkala is an academic researcher from International Centre for Genetic Engineering and Biotechnology. The author has contributed to research in topics: Antibody & Medicine. The author has an hindex of 6, co-authored 13 publications receiving 546 citations. Previous affiliations of Kamalvishnu P. Gottimukkala include Indian Institute of Science & Indian Institute of Science Education and Research, Pune.
Papers
More filters
Journal ArticleDOI
Senolytic therapy alleviates Aβ-associated oligodendrocyte progenitor cell senescence and cognitive deficits in an Alzheimer's disease model.
Peisu Zhang,Yuki Kishimoto,Ioannis Grammatikakis,Kamalvishnu P. Gottimukkala,Roy G. Cutler,Shiliang Zhang,Kotb Abdelmohsen,Vilhelm A. Bohr,Jyoti Misra Sen,Jyoti Misra Sen,Myriam Gorospe,Mark P. Mattson,Mark P. Mattson +12 more
TL;DR: A role for Aβ-induced OPC cell senescence in neuroinflammation and cognitive deficits in AD is suggested, and a potential therapeutic benefit of senolytic treatments is suggested.
Journal ArticleDOI
Global Regulator SATB1 Recruits β-Catenin and Regulates TH2 Differentiation in Wnt-Dependent Manner
Dimple Notani,Kamalvishnu P. Gottimukkala,Ranveer Singh Jayani,Amita Limaye,Madhujit V. Damle,Sameet Mehta,Prabhat Kumar Purbey,Jomon Joseph,Sanjeev Galande +8 more
TL;DR: Chromatin organizer SATB1 and Wnt transducer β-catenin form a complex and regulate expression of GATA3 and TH2 cytokines in Wnt-dependent manner and orchestrate TH2 lineage commitment.
Journal ArticleDOI
SATB1 dictates expression of multiple genes including IL-5 involved in human T helper cell differentiation.
Helena Ahlfors,Amita Limaye,Laura L. Elo,Laura L. Elo,Soile Tuomela,Mithila Burute,Kamalvishnu P. Gottimukkala,Dimple Notani,Omid Rasool,Sanjeev Galande,Riitta Lahesmaa +10 more
TL;DR: It is demonstrated that, during the early Th2 cell differentiation, IL-5 expression is repressed through direct binding of SATB1 to the IL- 5 promoter, and it is suggested that a competitive mechanism involving SATB 1 and GATA3 regulates IL-4 transcription.
Journal ArticleDOI
Chromatin organizer SATB1 is an important determinant of T-cell differentiation
TL;DR: This review focuses on the role of the T lineage‐enriched chromatin organizer and regulator SATB1 in T‐cell differentiation and discusses how regulation of the activity of SATB 1 has a critical role in driving these two important differentiation pathways in T cells.
Journal ArticleDOI
Characterization of neutralizing versus binding antibodies and memory B cells in COVID-19 recovered individuals from India.
Kaustuv Nayak,Kamalvishnu P. Gottimukkala,Sanjeev Kumar,Elluri Seetharami Reddy,Venkata Viswanadh Edara,Robert C. Kauffman,Katharine Floyd,Grace Mantus,Deepali Savargaonkar,Pawan Kumar Goel,Satyam Arora,Manju Rahi,Carl W. Davis,Susanne L. Linderman,Jens Wrammert,Mehul S. Suthar,Rafi Ahmed,Amit Sharma,Kaja Murali-Krishna,Anmol Chandele +19 more
TL;DR: In this paper, the authors examined SARS-CoV-2 neutralizing antibodies, IgG, IgM, IgA and memory B cells in COVID-19 recovered individual from India.