K
Karol Nass
Researcher at Paul Scherrer Institute
Publications - 83
Citations - 8229
Karol Nass is an academic researcher from Paul Scherrer Institute. The author has contributed to research in topics: Femtosecond & Laser. The author has an hindex of 32, co-authored 74 publications receiving 7116 citations. Previous affiliations of Karol Nass include Max Planck Society & University of Hamburg.
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Journal ArticleDOI
Room temperature XFEL crystallography reveals asymmetry in the vicinity of the two phylloquinones in photosystem I.
Stephen Keable,Adrian Kölsch,Philipp S. Simon,M. Dasgupta,Ruchira Chatterjee,Senthil Kumar Subramanian,Rana Hussein,Mohamed Ibrahim,In-Sik Kim,Isabel Bogacz,Hiroki Makita,Cindy C. Pham,Franklin D. Fuller,Sheraz Gul,Daniel W. Paley,Louise Lassalle,Kyle D. Sutherlin,Asmit Bhowmick,Nigel W. Moriarty,Iris D. Young,Iris D. Young,Johannes Blaschke,Casper de Lichtenberg,Casper de Lichtenberg,Petko Chernev,Mun Hon Cheah,Sehan Park,Gisu Park,Jangwoo Kim,Sang Jae Lee,Jaehyun Park,Kensuke Tono,Shigeki Owada,Mark S. Hunter,Alexander Batyuk,Roland Alex Oggenfuss,Mathias Sander,Serhane Zerdane,Dmitry Ozerov,Karol Nass,Henrik T. Lemke,Roman Mankowsky,Aaron S. Brewster,Johannes Messinger,Nicholas K. Sauter,Vittal K. Yachandra,Junko Yano,Athina Zouni,Jan Kern +48 more
TL;DR: In this paper, the structure of cyanobacterial photosystem I at room temperature (RT) using femtosecond X-ray pulses from an Xray free electron laser (XFEL) was determined.
Journal ArticleDOI
Ultrafast structural changes direct the first molecular events of vision
Thomas Gruhl,Tobias Weinert,Matthew J. Rodrigues,Christopher J. Milne,Giorgia Ortolani,Karol Nass,Eriko Nango,Saumik Sen,P. Johnson,Claudio Cirelli,Antonia Furrer,S. Mous,Petr Skopintsev,Daniel James,Florian S. N. Dworkowski,Petra Båth,Demet Kekilli,Dmitry Ozerov,Rie Tanaka,Hannah Glover,Camila Bacellar,Steffen Brünle,Cecilia M. Casadei,Azeglio D Diethelm,Dardan Gashi,Guillaume Gotthard,Ramon Guixà-González,Yasumasa Joti,Victoria Kabanova,Gregor Knopp,Elena Lesca,Pikyee Ma,Isabelle Martiel,Jonas Mühle,Shigeki Owada,Filip Pamula,Daniel Sarabi,Oliver Tejero,Ching-Ju Tsai,Niranjan Varma,Anna Wach,Sébastien Boutet,Kensuke Tono,Przemyslaw Nogly,Xavier Deupi,So Iwata,Richard Neutze,Jörg Standfuss,Gebhard F. X. Schertler,Valerie Panneels +49 more
TL;DR: In this paper , the authors used ultrafast time-resolved crystallography at room temperature to determine how an isomerized twisted all-trans retinal stores the photon energy that is required to initiate the protein conformational changes associated with the formation of the G protein-binding signalling state.
Radiation damage in ferredoxin microcrystals using high intensity X-FEL beams
Karol Nass,Stefan P. Hau-Riege +1 more
TL;DR: Difference electron density maps calculated from high-dose SFX and synchrotron data show peaks at the iron positions of the clusters, indicative of decrease of atomic scattering factors due to ionization, suggestive of an influence of the molecular bonding and geometry on the atomic displacement dynamics following initial photoionization.
Journal ArticleDOI
Expression, purification and crystallization of CTB-MPR, a candidate mucosal vaccine component against HIV-1.
Ho-Hsien Lee,Irene Cherni,HongQi Yu,Raimund Fromme,Jeffrey D. Doran,Ingo Grotjohann,Michele Mittman,Shibom Basu,Arpan Deb,Katerina Dörner,Andrew Aquila,Anton Barty,Sébastien Boutet,Henry N. Chapman,R. Bruce Doak,Mark S. Hunter,Daniel James,Richard A. Kirian,Christopher Kupitz,Robert M. Lawrence,Haiguang Liu,Karol Nass,Ilme Schlichting,Kevin Schmidt,M. Marvin Seibert,Robert L. Shoeman,John C. H. Spence,Francesco Stellato,Uwe Weierstall,Garth J. Williams,Chun Hong Yoon,Dingjie Wang,Nadia A. Zatsepin,Brenda G. Hogue,Nobuyuki Matoba,Petra Fromme,Tsafrir S. Mor +36 more
TL;DR: Femtosecond X-ray crystallography allows structural analysis of a difficult-to-crystallize fusion protein that is a potential component of a candidate HIV-1 subunit vaccine.
Journal ArticleDOI
Pink-beam serial femtosecond crystallography for accurate structure-factor determination at an X-ray free-electron laser.
Karol Nass,Camila Bacellar,Claudio Cirelli,Florian S. N. Dworkowski,Y. Gevorkov,Daniel James,Philip J. M. Johnson,Demet Kekilli,Gregor Knopp,Isabelle Martiel,Dmitry Ozerov,A. Tolstikova,Laura Vera,Tobias Weinert,Oleksandr Yefanov,Jörg Standfuss,Sven Reiche,Christopher J. Milne +17 more
TL;DR: In this article, the capability of the Swiss X-ray free-electron laser (SwissFEL) was used to generate large-bandwidth x-ray pulses [Δλ/λ = 2.2% full width at half-maximum (FWHM), which were applied in serial femtosecond crystallography (SFX) with the aim of improving the partiality of Bragg spots and thus decreasing sample consumption while maintaining the data quality.