Dardan Gashi

TL;DR: The principal mechanism of isomerization in this prototypical retinal-binding protein has direct relevance for all other members of this important family of membrane proteins, and it provides insight into how protein environments catalyze photochemical reactions in general.

TL;DR: It is demonstrated that serial millisecond crystallography at a synchrotron beamline equipped with high-viscosity injector and high frame-rate detector allows typical crystallographic experiments to be performed at room-temperature.

TL;DR: Crystallographic ‘snapshots’ taken at intervals of femtoseconds to milliseconds after activation show how a light-activated sodium pump carries sodium ions across the cell membrane and provide direct molecular insight into the dynamics of active cation transport across biological membranes.

TL;DR: A molecular movie reveals how ion transport is initiated and controlled in a chloride-pumping rhodopsin, and proposes key mechanistic features enabling finely controlled chloride transport across the cell membrane in this light-powered chloride ion pump.

TL;DR: An organometallic multicore Cu complex comprising Cu–C and Cu–P bonds as luminophore is investigated by pump-probe X-ray techniques at three different facilities deriving a complete picture of the charge transfer in the triplet excited state.