K
Katherine S. Elliott
Researcher at University of Oxford
Publications - 51
Citations - 14778
Katherine S. Elliott is an academic researcher from University of Oxford. The author has contributed to research in topics: Genome-wide association study & Population. The author has an hindex of 26, co-authored 43 publications receiving 13239 citations. Previous affiliations of Katherine S. Elliott include Wellcome Trust Centre for Human Genetics.
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Journal ArticleDOI
Evaluation of association of HNF1B variants with diverse cancers: collaborative analysis of data from 19 genome-wide association studies.
Katherine S. Elliott,Eleftheria Zeggini,Eleftheria Zeggini,Mark I. McCarthy,Mark I. McCarthy,Julius Gudmundsson,Patrick Sulem,Simon N. Stacey,Steinunn Thorlacius,Laufey T. Amundadottir,Henrik Grönberg,Jianfeng Xu,Valerie Gaborieau,Rosalind A. Eeles,David E. Neal,Jenny L Donovan,Freddie C. Hamdy,Kenneth Muir,Shih-Jen Hwang,Margaret R. Spitz,Brent W. Zanke,Brent W. Zanke,Luis G. Carvajal-Carmona,Kevin M. Brown,Australian Melanoma Family Study Investigators,Nicholas K. Hayward,Stuart MacGregor,Ian Tomlinson,Mathieu Lemire,Christopher I. Amos,Joanne M. Murabito,William B. Isaacs,Douglas F. Easton,Paul Brennan,Rosa B. Barkardottir,Daniel F. Gudbjartsson,Thorunn Rafnar,David J. Hunter,Stephen J. Chanock,Kari Stefansson,John P. A. Ioannidis,John P. A. Ioannidis +41 more
TL;DR: The examined HNF1B variants have a highly specific effect on prostate cancer risk with no apparent association with any of the other studied cancer types.
Journal ArticleDOI
Early childhood epilepsies: epidemiology, classification, aetiology, and socio-economic determinants
Joseph D. Symonds,Katherine S. Elliott,Jay Shetty,Martin Armstrong,Andreas Brunklaus,Ioana Cutcutache,Louise A Diver,Liam Dorris,Sarah L. Gardiner,Alice Jollands,Shelagh Joss,Martin Kirkpatrick,Martin Kirkpatrick,Ailsa McLellan,S. MacLeod,Mary O'Regan,Matthew Page,Elizabeth Pilley,Elizabeth Pilley,Daniela T. Pilz,Elma Stephen,Kirsty Stewart,Houman Ashrafian,Julian C. Knight,Sameer M. Zuberi +24 more
TL;DR: In this paper, a 3-year, multicentre prospective cohort study, involving all children under 3 years of age in Scotland presenting with epilepsies, was conducted, and the adjusted incidence of epilepsy presenting in the first three years of life was 239 per 100,000 live births [95% confidence interval (CI) 216-263].
Journal ArticleDOI
Rare variation at the TNFAIP3 locus and susceptibility to rheumatoid arthritis
John Bowes,Robert Lawrence,Robert Lawrence,Stephen Eyre,Kalliope Panoutsopoulou,Gisela Orozco,Katherine S. Elliott,Xiayi Ke,Andrew P. Morris,Wendy Thomson,Jane Worthington,Anne Barton,Eleftheria Zeggini +12 more
TL;DR: This study supports the application of low frequency variant collapsing methods to genome-wide SNP datasets as a means of exploiting data that are routinely ignored.
Journal ArticleDOI
Genetic variation in PARL influences mitochondrial content
Joanne E. Curran,Jeremy B. M. Jowett,Lawrence J. Abraham,Luke A. Diepeveen,Katherine S. Elliott,Thomas D. Dyer,Lyndal Kerr-Bayles,Matthew P. Johnson,Anthony G. Comuzzie,Eric K. Moses,Ken Walder,Gregory Collier,John Blangero,Ahmed H. Kissebah +13 more
TL;DR: Assessment of the influence of variation in the PARL gene on mitochondrial content suggests that genetic variation within PARL influences mitochondrial abundance and integrity.
Journal ArticleDOI
Severe Insulin Resistance and Intrauterine Growth Deficiency Associated With Haploinsufficiency for INSR and CHN2 New Insights Into Synergistic Pathways Involved in Growth and Metabolism
Sara G.I. Suliman,Juraj Stanik,Laura J. McCulloch,Natalie Wilson,Emma L. Edghill,N Misovicova,Daniela Gasperikova,Vilja Sandrikova,Katherine S. Elliott,L Barak,Sian Ellard,Emanuela V. Volpi,Iwar Klimes,Anna L. Gloyn +13 more
TL;DR: A likely digenic cause of insulin resistance and growth deficiency resulting from the combined heterozygous disruption of INSR and CHN2 is presented, implicating ChN2 for the first time as a key element of proximal insulin signaling in vivo.