K
Katsuhiko Muraki
Researcher at Aichi Gakuin University
Publications - 120
Citations - 5602
Katsuhiko Muraki is an academic researcher from Aichi Gakuin University. The author has contributed to research in topics: Transient receptor potential channel & Depolarization. The author has an hindex of 37, co-authored 115 publications receiving 4790 citations. Previous affiliations of Katsuhiko Muraki include University of Leeds & Kyoto Prefectural University of Medicine.
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Journal ArticleDOI
Piezo1 integration of vascular architecture with physiological force
Jing Li,Bing Hou,Sarka Tumova,Katsuhiko Muraki,Alexander F. Bruns,Melanie J. Ludlow,Alicia Sedo,Adam J. Hyman,Lynn McKeown,Richard S. Young,Richard S. Young,Nadira Yuldasheva,Yasser Majeed,Lesley A. Wilson,Baptiste Rode,Marc A. Bailey,Hyejeong R. Kim,Zhaojun Fu,Deborah Angela Louise Carter,Jan Bilton,Helen Imrie,Paul Ajuh,T. Neil Dear,Richard M Cubbon,Mark T. Kearney,K. Raj Prasad,Paul C. Evans,Justin F. X. Ainscough,David J. Beech +28 more
TL;DR: Piezo1 channels are shown as sensors of frictional force (shear stress) and determinants of vascular structure in both development and adult physiology and the data suggest that Piezo 1 channels function as pivotal integrators in vascular biology.
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TRPV2 Is a Component of Osmotically Sensitive Cation Channels in Murine Aortic Myocytes
Katsuhiko Muraki,Yuko Iwata,Yuki Katanosaka,Tomohiro Ito,Susumu Ohya,Munekazu Shigekawa,Yuji Imaizumi +6 more
TL;DR: Evidence that a vanilloid receptor (TRPV) homologue, TRPV2 is expressed in vascular smooth muscle cells, and that it can be activated by membrane stretch is provided.
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Non-selective cationic channels of smooth muscle and the mammalian homologues of Drosophila TRP
TL;DR: Current knowledge of these smooth muscle cationic channels are summarized, and the hypothesis that the underlying genes are homologues of Drosophila TRP (transient receptor potential) is evaluated to prove a leap forward for strategies aimed at developing new selective pharmacological agents and understanding the activation mechanisms and functions of these channels in physiological systems.
Journal ArticleDOI
Piezo1 Integration of Vascular Architecture with Physiological Force
TL;DR: The mechanisms by which physical forces regulate endothelial cells to determine the complexities of vascular structure and function are enigmatic as mentioned in this paper, and it has been suggested that sensory neurons have suggested Piezo pr...
Journal ArticleDOI
Englerin A is a Potent and Selective Activator of TRPC4 and TRPC5 Calcium Channels
Yasemin Akbulut,Hannah J. Gaunt,Katsuhiko Muraki,Melanie J. Ludlow,Mohamed S Amer,Alexander F. Bruns,Naveen S. Vasudev,Lea Radtke,Matthieu Willot,Sven Hahn,Tobias Seitz,Slava Ziegler,Mathias Christmann,David J. Beech,Herbert Waldmann +14 more
TL;DR: The unexpected possibility for the rapid and selective killing of renal cancer cells through activation of calcium-permeable nonselective transient receptor potential canonical (TRPC) calcium channels by the sesquiterpene (-)-englerin A is shown.