S
Stephanie Mulligan
Researcher at J. Craig Venter Institute
Publications - 7
Citations - 2834
Stephanie Mulligan is an academic researcher from J. Craig Venter Institute. The author has contributed to research in topics: Aspergillus fumigatus & Serotype. The author has an hindex of 6, co-authored 7 publications receiving 2694 citations. Previous affiliations of Stephanie Mulligan include Washington University in St. Louis.
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Journal ArticleDOI
Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus
William C. Nierman,William C. Nierman,Arnab Pain,Michael J. Anderson,Jennifer R. Wortman,Jennifer R. Wortman,H. Stanley Kim,H. Stanley Kim,Javier Arroyo,Matthew Berriman,Keietsu Abe,David B. Archer,Clara Bermejo,Joan W. Bennett,Paul Bowyer,Dan Chen,Dan Chen,Matthew Collins,Richard Coulsen,Robert L. Davies,Paul S. Dyer,Mark L. Farman,Nadia Fedorova,Nadia Fedorova,Natalie D. Fedorova,Natalie D. Fedorova,T. Feldblyum,T. Feldblyum,Reinhard Fischer,Nigel Fosker,Audrey Fraser,José Luis García,María Josefa Marcos García,Ariette Goble,Gustavo H. Goldman,Katsuya Gomi,Sam Griffith-Jones,R. Gwilliam,Brian J. Haas,Brian J. Haas,Hubertus Haas,David Harris,H. Horiuchi,Jiaqi Huang,Jiaqi Huang,Sean Humphray,Javier Jiménez,Nancy P. Keller,H. Khouri,H. Khouri,Katsuhiko Kitamoto,Tetsuo Kobayashi,Sven Konzack,Resham Kulkarni,Resham Kulkarni,Toshitaka Kumagai,Anne Lafton,Jean-Paul Latgé,Weixi Li,Angela Lord,Charles Lu,Charles Lu,William H. Majoros,William H. Majoros,Gregory S. May,Bruce L. Miller,Yasmin Ali Mohamoud,Yasmin Ali Mohamoud,María Molina,Michel Monod,Isabelle Mouyna,Stephanie Mulligan,Stephanie Mulligan,Lee Murphy,Susan O'Neil,Ian T. Paulsen,Ian T. Paulsen,Miguel A. Peñalva,Mihaela Pertea,Mihaela Pertea,Claire Price,Bethan L. Pritchard,Michael A. Quail,Ester Rabbinowitsch,Neil Rawlins,Marie Adele Rajandream,Utz Reichard,Hubert Renauld,Geoffrey D. Robson,Santiago Rodríguez de Córdoba,José Manuel Rodríguez-Peña,Catherine M. Ronning,Catherine M. Ronning,Simon Rutter,Steven L. Salzberg,Steven L. Salzberg,Miguel del Nogal Sánchez,Juan C. Sánchez-Ferrero,David L. Saunders,Kathy Seeger,Rob Squares,S. Squares,Michio Takeuchi,Fredj Tekaia,Geoffrey Turner,Carlos R. Vázquez de Aldana,J. Weidman,J. Weidman,Owen White,Owen White,John Woodward,Jae-Hyuk Yu,Claire M. Fraser,Claire M. Fraser,James E. Galagan,Kiyoshi Asai,Masayuki Machida,Neil Hall,Neil Hall,Bart Barrell,David W. Denning +120 more
TL;DR: The Af293 genome sequence provides an unparalleled resource for the future understanding of this remarkable fungus and revealed temperature-dependent expression of distinct sets of genes, as well as 700 A. fumigatus genes not present or significantly diverged in the closely related sexual species Neosartorya fischeri, many of which may have roles in the pathogenicity phenotype.
Journal ArticleDOI
Complete genome sequence and comparative genomic analysis of an emerging human pathogen, serotype V Streptococcus agalactiae
Hervé Tettelin,Vega Masignani,Michael J. Cieslewicz,Jonathan A. Eisen,Jonathan A. Eisen,Scott N. Peterson,Scott N. Peterson,Michael R. Wessels,Ian T. Paulsen,Ian T. Paulsen,Karen E. Nelson,Immaculada Margarit,Timothy D. Read,Lawrence C. Madoff,Alex M. Wolf,Maureen J. Beanan,Lauren M. Brinkac,Sean C. Daugherty,Robert T. DeBoy,A. Scott Durkin,James F. Kolonay,Ramana Madupu,Matthew R. Lewis,Diana Radune,Nadezhda B. Fedorova,David J. Scanlan,Hoda Khouri,Stephanie Mulligan,Heather A. Carty,Robin T. Cline,Susan Van Aken,John Gill,Maria Scarselli,Marirosa Mora,Emilia Tiziana Iacobini,Cecilia Brettoni,Giuliano Galli,Massimo Mariani,Filippo Vegni,Domenico Maione,C. Daniela Rinaudo,Rino Rappuoli,John L. Telford,Dennis L. Kasper,Guido Grandi,Claire M. Fraser,Claire M. Fraser +46 more
TL;DR: In silico analyses, combined with comparative genome hybridization experiments between the sequenced serotype V strain 2603 V/R and 19 S. agalactiae strains from several serotypes using whole-genome microarrays, revealed the genetic heterogeneity among S. agriculture, provided insights into the evolution of virulence mechanisms.
Journal ArticleDOI
Comparative Genomics of Emerging Human Ehrlichiosis Agents
Julie C. Dunning Hotopp,Mingqun Lin,Ramana Madupu,Jonathan Crabtree,Samuel V. Angiuoli,Jonathan A. Eisen,Rekha Seshadri,Qinghu Ren,Martin Wu,Teresa Utterback,Shannon Smith,Matthew R. Lewis,Hoda Khouri,Chunbin Zhang,Hua Niu,Quan Lin,Norio Ohashi,Ning Zhi,William C. Nelson,Lauren M. Brinkac,Robert J. Dodson,M. J. Rosovitz,Jaideep P. Sundaram,Sean C. Daugherty,Tanja M. Davidsen,Anthony S. Durkin,Michelle L. Gwinn,Daniel H. Haft,Jeremy D. Selengut,Steven A. Sullivan,Nikhat Zafar,Liwei Zhou,Faiza H. Benahmed,Heather C. Forberger,Rebecca A. Halpin,Stephanie Mulligan,Jeffrey M. Robinson,Owen White,Yasuko Rikihisa,Hervé Tettelin +39 more
TL;DR: Analysis identified proteins potentially involved in vacuole confinement of the Anaplasmataceae, a life cycle involving a hematophagous vector, vertebrate pathogenesis, human pathogenesis and lack of transovarial transmission, which provide significant insights into the biology of these obligate intracellular pathogens.
Journal ArticleDOI
Skewed genomic variability in strains of the toxigenic bacterial pathogen, Clostridium perfringens
Garry S. A. Myers,David A. Rasko,David A. Rasko,Jackie K. Cheung,Jacques Ravel,Rekha Seshadri,Robert T. DeBoy,Qinghu Ren,John J. Varga,Milena M. Awad,Lauren M. Brinkac,Sean C. Daugherty,Daniel H. Haft,Robert J. Dodson,Ramana Madupu,William C. Nelson,M. J. Rosovitz,Steven A. Sullivan,Hoda Khouri,George Dimitrov,Kisha Watkins,Stephanie Mulligan,Jonathan L. Benton,Diana Radune,Derek J. Fisher,Helen S. Atkins,Thomas J. Hiscox,B. Helen Jost,Stephen J. Billington,J. Glenn Songer,Bruce A. McClane,Richard W. Titball,Julian I. Rood,Stephen B. Melville,Ian T. Paulsen +34 more
TL;DR: Significant differences between the strains include numerous novel mobile elements and genes encoding metabolic capabilities, strain-specific extracellular polysaccharide capsule, sporulation factors, toxins, and other secreted enzymes, providing substantial insight into this medically important bacterial pathogen.
Journal ArticleDOI
Genome degradation in Brucella ovis corresponds with narrowing of its host range and tissue tropism.
Renée M. Tsolis,Rekha Seshadri,Renato L. Santos,Renato L. Santos,Félix J. Sangari,Juan M. García Lobo,Maarten F. de Jong,Qinghu Ren,Garry S. A. Myers,Lauren M. Brinkac,William C. Nelson,Robert T. DeBoy,Samuel V. Angiuoli,Hoda Khouri,George Dimitrov,Jeffrey R. Robinson,Stephanie Mulligan,Richard L. Walker,Philip E. Elzer,Karl A. Hassan,Ian T. Paulsen,Ian T. Paulsen +21 more
TL;DR: The results suggest that inactivation of genes involved in nutrient acquisition and utilization, cell envelope structure and urease may have played a role in narrowing of the tissue tropism and host range of B. ovis.