K
Kazuo Tsubota
Researcher at Keio University
Publications - 1421
Citations - 57308
Kazuo Tsubota is an academic researcher from Keio University. The author has contributed to research in topics: Cornea & Visual acuity. The author has an hindex of 105, co-authored 1379 publications receiving 48991 citations. Previous affiliations of Kazuo Tsubota include Chiba University & Showa University.
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Journal ArticleDOI
Genetic Spectrum of EYS-associated Retinal Disease in a Large Japanese Cohort: Identification of Disease-associated Variants with Relatively High Allele Frequency
Lizhu Yang,Kaoru Fujinami,Shinji Ueno,Kazuki Kuniyoshi,Takaaki Hayashi,Mineo Kondo,Atsushi Mizota,Nobuhisa Nao-i,Kei Shinoda,Kei Shinoda,Shuhei Kameya,Yu Fujinami-Yokokawa,Yu Fujinami-Yokokawa,Xiao Liu,Xiao Liu,Xiao Liu,Gavin Arno,Nikolas Pontikos,Nikolas Pontikos,Nikolas Pontikos,Taro Kominami,Hiroko Terasaki,Hiroyuki Sakuramoto,Satoshi Katagiri,Kei Mizobuchi,Natsuko Nakamura,Natsuko Nakamura,Go Mawatari,Toshihide Kurihara,Kazuo Tsubota,Yozo Miyake,Kazutoshi Yoshitake,Takeshi Iwata,Kazushige Tsunoda +33 more
TL;DR: The presence of EYS variants with relatively high AF highlights the importance of considering the pathogenicity of non-rare variants in relatively prevalent Mendelian disorders.
Journal ArticleDOI
Tear film and ocular surface abnormalities after eyelid tattooing.
TL;DR: A 45-year-old woman who underwent eyelid tattooing 20 years earlier presented with decreased left vision and eye discomfort and her initial examination revealed tear instability with increased ocular surface staining scores and advanced tear film lipid layer abnormality in both eyes.
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Expression and localization of aging markers in lacrimal gland of chronic graft-versus-host disease
Masataka Kawai,Yoko Ogawa,Shigeto Shimmura,Shigeki Ohta,Takanori Suzuki,Naoshi Kawamura,Masataka Kuwana,Yutaka Kawakami,Kazuo Tsubota +8 more
TL;DR: It is suggested that changes that typically appear with advanced age occur earlier in the lives of mice with lacrimal gland cGVHD, particularly in the young mice.
Journal ArticleDOI
Functional visual acuity measurement in cataract and intraocular lens implantation.
TL;DR: FVA measurement is an effective and noninvasive test that reflects the complaints of blurring/glare and postoperative satisfaction in patients with mild cataract and a new continuous FVA measurement system for the assessment of visual performance is discussed.
Journal Article
Characterization of cultivated murine lacrimal gland epithelial cells.
Shinya Kobayashi,Tetsuya Kawakita,Motoko Kawashima,Naoko Okada,Kenji Mishima,Ichiro Saito,Masataka Ito,Shigeto Shimmura,Kazuo Tsubota +8 more
TL;DR: Adult mouse lacrimal gland epithelial cells were successfully cultivated in cholera toxin-containing medium, and were observed to form spheres from single cells.