K
Kenneth J. Pienta
Researcher at Johns Hopkins University School of Medicine
Publications - 751
Citations - 72579
Kenneth J. Pienta is an academic researcher from Johns Hopkins University School of Medicine. The author has contributed to research in topics: Prostate cancer & Cancer. The author has an hindex of 127, co-authored 671 publications receiving 64531 citations. Previous affiliations of Kenneth J. Pienta include Rutgers University & Harper University Hospital.
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Journal ArticleDOI
Development of an Automated and Sensitive Microfluidic Device for Capturing and Characterizing Circulating Tumor Cells (CTCs) from Clinical Blood Samples
Priya Gogoi,Saedeh Sepehri,Yi Zhou,Michael A. Gorin,Carmela Paolillo,Carmela Paolillo,Ettore Capoluongo,Kyle Gleason,Austin Payne,Brian Boniface,Massimo Cristofanilli,Todd M. Morgan,Paolo Fortina,Paolo Fortina,Kenneth J. Pienta,Kalyan Handique,Yixin Wang +16 more
TL;DR: The integrated Celsee system represents a promising CTC technology for enumeration and molecular characterization using a microfluidic chip to enrich and characterize CTCs from blood samples of patients with metastatic breast, prostate and colorectal cancers.
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PSMA-RADS Version 1.0: A Step Towards Standardizing the Interpretation and Reporting of PSMA–targeted PET Imaging Studies
TL;DR: A reporting and data system called PSMA-RADS version 1.0 is proposed, which is a framework for classifying PSma-targeted PET scans and individual findings into categories that reflect the likelihood of the presence of prostate cancer.
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Cancer as a complex adaptive system
Eric D. Schwab,Kenneth J. Pienta +1 more
TL;DR: Redefining the authors' perception of cancer may lead to a deeper understanding of the disease, and possibly result in novel methods of therapeutic intervention.
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In vivo visualization of metastatic prostate cancer and quantitation of disease progression in immunocompromised mice
Linda M. Kalikin,Abraham Schneider,Melissa A. Thakur,Yaron Fridman,Laura B. Griffin,Rodney L. Dunn,Thomas J. Rosol,Rajal B. Shah,Alnawaz Rehemtulla,Laurie K. McCauley,Kenneth J. Pienta +10 more
TL;DR: A comprehensive murine model is designed to monitor tumor location and expansion and calculated in vivo kinetics for tumor growth based on biophoton emissions and observed significantly faster growth of bone lesions and of overall tumor burden in young mice compared to old mice.
Journal ArticleDOI
Inhibition of prostate cancer bone metastasis by synthetic TF antigen mimic/galectin-3 inhibitor lactulose-L-leucine.
Olga V. Glinskii,Olga V. Glinskii,Sudha Sud,Valeri V. Mossine,Thomas P. Mawhinney,Douglas C. Anthony,Gennadi V. Glinsky,Kenneth J. Pienta,Vladislav V. Glinsky,Vladislav V. Glinsky +9 more
TL;DR: It is concluded that small-molecular-weight carbohydrate-based compounds targeting β-galactoside-mediated interactions could provide valuable means for controlling and preventing metastatic prostate cancer spread to the skeleton.