K
Kenneth J. Pienta
Researcher at Johns Hopkins University School of Medicine
Publications - 751
Citations - 72579
Kenneth J. Pienta is an academic researcher from Johns Hopkins University School of Medicine. The author has contributed to research in topics: Prostate cancer & Cancer. The author has an hindex of 127, co-authored 671 publications receiving 64531 citations. Previous affiliations of Kenneth J. Pienta include Rutgers University & Harper University Hospital.
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Journal ArticleDOI
Optimization of prostate cancer cell detection using multiplex tyramide signal amplification.
Sounak Roy,Sounak Roy,Haley D. Axelrod,Haley D. Axelrod,Kenneth C. Valkenburg,Sarah R. Amend,Kenneth J. Pienta +6 more
TL;DR: A novel immunofluorescence staining protocol to detect a panel of seven proteins on PCa tissue from primary tumor biopsies and metastatic lesion autopsy tissue, as well as cancer cells from liquidBiopsies is developed.
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High-Throughput Simultaneous mRNA Profiling Using nCounter Technology Demonstrates That Extracellular Vesicles Contain Different mRNA Transcripts Than Their Parental Prostate Cancer Cells.
Liang Dong,Liang Dong,Chung-Ying Huang,Eric J Johnson,Lei Yang,Richard C. Zieren,Richard C. Zieren,Kengo Horie,Kengo Horie,Chi-Ju Kim,Chi-Ju Kim,Sarah Warren,Sarah R. Amend,Wei Xue,Kenneth J. Pienta +14 more
TL;DR: In this paper, a new protocol using the NanoString low RNA input nCounter assay by which the targeted mRNA transcripts in extracellular vesicles can be efficiently and specifically amplified and then assayed for 770 mRNAs in one reaction.
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Beyond immune checkpoint blockade: New approaches to targeting host–tumor interactions in prostate cancer: Report from the 2014 Coffey–Holden prostate cancer Academy meeting
Andrea K. Miyahira,Haydn T. Kissick,Jennifer L. Bishop,David Y. Takeda,Christopher E. Barbieri,Jonathan W. Simons,Kenneth J. Pienta,Howard R. Soule +7 more
TL;DR: The 2014 Coffey–Holden Prostate Cancer Academy Meeting, held in La Jolla, CA from June 26 to 29, 2014, was themed: “Beyond Immune Checkpoint Blockade: New Approaches to Targeting Host–Tumor Interactions in Prostate cancer.”
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Erythropoietin Supports the Survival of Prostate Cancer, But Not Growth and Bone Metastasis
Yusuke Shiozawa,Samantha McGee,Michael J. Pienta,Natalie McGregor,Younghun Jung,Kenji Yumoto,Jingcheng Wang,Janice E. Berry,Kenneth J. Pienta,Russell S. Taichman +9 more
TL;DR: It is suggested that Epo may be useful for treating severe anemia in PCa patients without increasing metastatic risk, and in animal models of PCa metastasis, no evidence was found to support the hypothesis that EpO enhances metastasis.
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Recent advances in extracellular vesicle research for urological cancers: From technology to application
Liang Dong,Liang Dong,Richard C. Zieren,Yanqing Wang,Theo M. de Reijke,Wei Xue,Kenneth J. Pienta +6 more
TL;DR: This comprehensive review aims to give an update of recent advances in EV technologies and summarize the state-of-the-art knowledge of EVs related to prostate cancer, bladder cancer and kidney cancer, particularly focusing on the potential of EV as biomarkers and their biological roles in promoting cancer and metastasis.