K
Kenneth J. Pienta
Researcher at Johns Hopkins University School of Medicine
Publications - 751
Citations - 72579
Kenneth J. Pienta is an academic researcher from Johns Hopkins University School of Medicine. The author has contributed to research in topics: Prostate cancer & Cancer. The author has an hindex of 127, co-authored 671 publications receiving 64531 citations. Previous affiliations of Kenneth J. Pienta include Rutgers University & Harper University Hospital.
Papers
More filters
Proceedings ArticleDOI
Abstract 4005: HDAC inhibitors regulate M2 tumor-associated macrophage function through histone acetylation
TL;DR: Using M2 macrophages derived from human CD14 + monocytes, it is found that SAHA regulates M1 macrophage polarization and function through alteration of histone acetylation, laying the foundation for using epigenetic regulators to modulate the tumor microenvironment and advance cancer medicine.
Journal ArticleDOI
Results of a phase II trial of neoadjuvant abiraterone + prednisone+ enzalutamide + leuprolide (APEL) versus enzalutamide + leuprolide (EL) for patients with high-risk localized prostate cancer (PC) undergoing radical prostatectomy (RP).
Rana R. McKay,Wanling Xie,Rosina T. Lis,Huihui Ye,Zhenwei Zhang,Quoc-Dien Trinh,Steven L. Chang,Lauren C. Harshman,Ashley E. Ross,Kenneth J. Pienta,Daniel W. Lin,William J. Ellis,Robert B. Montgomery,Peter Chang,Andrew A. Wagner,Glenn J. Bubley,Adam S. Kibel,Mary-Ellen Taplin +17 more
TL;DR: This multicenter randomized phase II trial evaluates the impact of second generation hormone therapy on RP pathologic outcomes and results include PSA response, surgical staging at RP, positive margin rate, and safety.
Journal ArticleDOI
Selection-free method reveals phenotypic diversity among prostate cancer circulating tumour cells
TL;DR: Concerns about the specificity of these CTC assays are reported, as it has been reported that patients with benign conditions, such as inflammatory bowel disease, have circulating epithelial cells that can mimic CTCs.
Journal Article
The Emergence of Polyploid Giant Cancer Cells as the Reservoir of Theraputic Resistance
Journal ArticleDOI
Publisher Correction: 3D Shape Modeling for Cell Nuclear Morphological Analysis and Classification.
Alexandr A. Kalinin,Ari Allyn-Feuer,Alex Ade,Gordon Victor Fon,Walter Meixner,David S. Dilworth,Syed Husain,Jeffrey R. de Wet,Gerald A. Higgins,Gen Zheng,Amy Creekmore,John W. Wiley,James E. Verdone,Robert W. Veltri,Kenneth J. Pienta,Donald S. Coffey,Brian D. Athey,Ivo D. Dinov +17 more
TL;DR: A correction to this article has been published and is linked from the HTML and PDF versions of this paper.