Kira S. Makarova

TL;DR: Deinococcus radiodurans represents an organism in which all systems for DNA repair, DNA damage export, desiccation and starvation recovery, and genetic redundancy are present in one cell.

TL;DR: Comparison of C. acetobutylicum to Bacillus subtilis reveals significant local conservation of gene order, which has not been seen in comparisons of other genomes with similar, or, in some cases closer, phylogenetic proximity.

TL;DR: Functional and evolutionary patterns in the recently constructed set of 5,873 clusters of predicted orthologs (eukaryotic orthologous groups or KOGs) from seven eukaryosis genomes are examined, revealing a conserved core of largely essential eukARYotic genes as well as major diversification and innovation associated with evolution of eUKaryotic genomes.

TL;DR: A comprehensive census of class 2 types and class 2 subtypes in complete and draft bacterial and archaeal genomes is presented, evolutionary scenarios for the independent origin of different class 2 CRISPR–Cas systems from mobile genetic elements are outlined, and an amended classification and nomenclature of CRISpr–Cas is proposed.

TL;DR: An extensive comparative sequence analysis of the Deinococcus genome suggests that several different biological mechanisms contribute to the multiple DNA repair-dependent phenotypes of this organism.