K
Kustaa Hietala
Researcher at University of Helsinki
Publications - 33
Citations - 2135
Kustaa Hietala is an academic researcher from University of Helsinki. The author has contributed to research in topics: Type 1 diabetes & Diabetic retinopathy. The author has an hindex of 20, co-authored 32 publications receiving 1854 citations. Previous affiliations of Kustaa Hietala include Baker IDI Heart and Diabetes Institute & Helsinki University Central Hospital.
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Journal ArticleDOI
The Presence and Severity of Chronic Kidney Disease Predicts All-Cause Mortality in Type 1 Diabetes
Per-Henrik Groop,Per-Henrik Groop,Merlin C. Thomas,John Moran,Johan Wadén,Johan Wadén,Lena M. Thorn,Lena M. Thorn,Ville-Petteri Mäkinen,Ville-Petteri Mäkinen,Milla Rosengård-Bärlund,Milla Rosengård-Bärlund,Markku Saraheimo,Markku Saraheimo,Kustaa Hietala,Kustaa Hietala,Outi Heikkilä,Outi Heikkilä,Carol Forsblom,Carol Forsblom +19 more
TL;DR: An independent graded association was observed between the presence and severity of kidney disease and mortality in a large contemporary cohort of individuals with type 1 diabetes, highlighting the clinical and public health importance of chronic kidney diseaseand its prevention in the management of type 2 diabetes.
Journal ArticleDOI
New susceptibility loci associated with kidney disease in type 1 diabetes.
Niina Sandholm,Niina Sandholm,Rany M. Salem,Rany M. Salem,Amy Jayne McKnight,Eoin P. Brennan,Carol Forsblom,Tamara Isakova,Gareth J. McKay,Winfred W. Williams,Denise M. Sadlier,Ville-Petteri Mäkinen,Ville-Petteri Mäkinen,Elizabeth Swan,Cameron D. Palmer,Cameron D. Palmer,Andrew P. Boright,Emma Ahlqvist,Harshal Deshmukh,Benjamin J. Keller,Huateng Huang,Aila J. Ahola,Emma Fagerholm,Daniel Gordin,Valma Harjutsalo,Valma Harjutsalo,Bing He,Outi Heikkilä,Kustaa Hietala,Janne P. Kytö,Päivi Lahermo,Markku Lehto,Raija Lithovius,Anne-May Österholm,Maija Parkkonen,Janne Pitkäniemi,Milla Rosengård-Bärlund,Markku Saraheimo,Cinzia Sarti,Jenny Söderlund,Aino Soro-Paavonen,Anna Syreeni,Lena M. Thorn,Heikki O. Tikkanen,Nina Tolonen,Karl Tryggvason,Jaakko Tuomilehto,Johan Wadén,Geoffrey V. Gill,Sarah L. Prior,Candace Guiducci,Daniel B. Mirel,Andrew M. Taylor,Andrew M. Taylor,S. Mohsen Hosseini,Hans-Henrik Parving,Hans-Henrik Parving,Peter Rossing,Peter Rossing,Lise Tarnow,Lise Tarnow,Claes Ladenvall,François Alhenc-Gelas,Pierre Lefebvre,Vincent Rigalleau,Ronan Roussel,David-Alexandre Trégouët,Anna Maestroni,Silvia Maestroni,Henrik Falhammar,Tianwei Gu,Anna Möllsten,D. Cimponeriu,Mihai Ioana,Maria Mota,Eugen Mota,Cristian Serafinceanu,Monica Stavarachi,Robert L. Hanson,Robert G. Nelson,Matthias Kretzler,Helen M. Colhoun,Nicolae Mircea Panduru,Harvest F. Gu,Kerstin Brismar,Gianpaolo Zerbini,Samy Hadjadj,Michel Marre,Michel Marre,Leif Groop,Maria Lajer,Shelley B. Bull,Daryl Waggott,Andrew D. Paterson,David A. Savage,Stephen C. Bain,Finian Martin,Joel N. Hirschhorn,Joel N. Hirschhorn,Catherine Godson,Jose C. Florez,Jose C. Florez,Per-Henrik Groop,Per-Henrik Groop,Alexander P. Maxwell,Alexander P. Maxwell +105 more
TL;DR: A meta-analysis of genome-wide association studies of T1D DN revealed association of two SNPs with ESRD in the AFF3 gene and an intergenic SNP on chromosome 15q26 between the genes RGMA and MCTP2, which represent new signals in the pathogenesis of DN.
Journal ArticleDOI
Deep Learning Fundus Image Analysis for Diabetic Retinopathy and Macular Edema Grading.
Jaakko Sahlsten,Joel Jaskari,Jyri Kivinen,Lauri Turunen,Esa Jaanio,Kustaa Hietala,Kimmo Kaski +6 more
TL;DR: It is suggested that a deep learning system could increase the cost-effectiveness of screening and diagnosis, while attaining higher than recommended performance, and that the system could be applied in clinical examinations requiring finer grading.
Journal ArticleDOI
Heritability of proliferative diabetic retinopathy
TL;DR: A familial clustering of proliferative retinopathy in patients with type 1 diabetes is found, suggesting that genetic factors play a role in its pathogenesis.
Journal ArticleDOI
Metabolic Syndrome as a Risk Factor for Cardiovascular Disease, Mortality, and Progression of Diabetic Nephropathy in Type 1 Diabetes
Lena M. Thorn,Carol Forsblom,Johan Wadén,Markku Saraheimo,Nina Tolonen,Kustaa Hietala,Per-Henrik Groop +6 more
TL;DR: The metabolic syndrome is a risk factor, beyond albuminuria, for cardiovascular morbidity and diabetes-related mortality in type 1 diabetes, after adjustment for traditional risk factors and diabetic nephropathy.