T
Tianwei Gu
Researcher at Nanjing University
Publications - 32
Citations - 743
Tianwei Gu is an academic researcher from Nanjing University. The author has contributed to research in topics: Type 2 diabetes & Diabetes mellitus. The author has an hindex of 11, co-authored 27 publications receiving 628 citations. Previous affiliations of Tianwei Gu include Karolinska University Hospital & Nanjing Medical University.
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Journal ArticleDOI
New susceptibility loci associated with kidney disease in type 1 diabetes.
Niina Sandholm,Niina Sandholm,Rany M. Salem,Rany M. Salem,Amy Jayne McKnight,Eoin P. Brennan,Carol Forsblom,Tamara Isakova,Gareth J. McKay,Winfred W. Williams,Denise M. Sadlier,Ville-Petteri Mäkinen,Ville-Petteri Mäkinen,Elizabeth Swan,Cameron D. Palmer,Cameron D. Palmer,Andrew P. Boright,Emma Ahlqvist,Harshal Deshmukh,Benjamin J. Keller,Huateng Huang,Aila J. Ahola,Emma Fagerholm,Daniel Gordin,Valma Harjutsalo,Valma Harjutsalo,Bing He,Outi Heikkilä,Kustaa Hietala,Janne P. Kytö,Päivi Lahermo,Markku Lehto,Raija Lithovius,Anne-May Österholm,Maija Parkkonen,Janne Pitkäniemi,Milla Rosengård-Bärlund,Markku Saraheimo,Cinzia Sarti,Jenny Söderlund,Aino Soro-Paavonen,Anna Syreeni,Lena M. Thorn,Heikki O. Tikkanen,Nina Tolonen,Karl Tryggvason,Jaakko Tuomilehto,Johan Wadén,Geoffrey V. Gill,Sarah L. Prior,Candace Guiducci,Daniel B. Mirel,Andrew M. Taylor,Andrew M. Taylor,S. Mohsen Hosseini,Hans-Henrik Parving,Hans-Henrik Parving,Peter Rossing,Peter Rossing,Lise Tarnow,Lise Tarnow,Claes Ladenvall,François Alhenc-Gelas,Pierre Lefebvre,Vincent Rigalleau,Ronan Roussel,David-Alexandre Trégouët,Anna Maestroni,Silvia Maestroni,Henrik Falhammar,Tianwei Gu,Anna Möllsten,D. Cimponeriu,Mihai Ioana,Maria Mota,Eugen Mota,Cristian Serafinceanu,Monica Stavarachi,Robert L. Hanson,Robert G. Nelson,Matthias Kretzler,Helen M. Colhoun,Nicolae Mircea Panduru,Harvest F. Gu,Kerstin Brismar,Gianpaolo Zerbini,Samy Hadjadj,Michel Marre,Michel Marre,Leif Groop,Maria Lajer,Shelley B. Bull,Daryl Waggott,Andrew D. Paterson,David A. Savage,Stephen C. Bain,Finian Martin,Joel N. Hirschhorn,Joel N. Hirschhorn,Catherine Godson,Jose C. Florez,Jose C. Florez,Per-Henrik Groop,Per-Henrik Groop,Alexander P. Maxwell,Alexander P. Maxwell +105 more
TL;DR: A meta-analysis of genome-wide association studies of T1D DN revealed association of two SNPs with ESRD in the AFF3 gene and an intergenic SNP on chromosome 15q26 between the genes RGMA and MCTP2, which represent new signals in the pathogenesis of DN.
Journal ArticleDOI
Effects of Osthole on Migration and Invasion in Breast Cancer Cells
TL;DR: It is found that Osthole is effective in inhibiting the migration and invasion of breast cancer cells by wound healing and transwellAssays and indicates a need for further evaluation of Osthole in breast cancer chemotherapy and chemoprevention.
Journal ArticleDOI
Impact of the Hypoxia-Inducible Factor-1 α (HIF1A) Pro582Ser Polymorphism on Diabetes Nephropathy
Harvest F. Gu,Xiaowei Zheng,Norhashimah Abu Seman,Tianwei Gu,Ileana Ruxandra Botusan,Vivekananda Gupta Sunkari,Ezarul Faradianna Lokman,Kerstin Brismar,Sergiu-Bogdan Catrina +8 more
TL;DR: It is demonstrated for the first time that HIF1A Pro582Ser polymorphism has an effect on DN, possibly by conferring a relative resistance to the repressive effect of glucose on HIF-1α.
Journal ArticleDOI
Increased DNA methylation levels of the insulin-like growth factor binding protein 1 gene are associated with type 2 diabetes in Swedish men.
Tianwei Gu,Harvest F. Gu,A. Hilding,Louise K. Sjöholm,Claes-Göran Östenson,Tomas J. Ekström,Kerstin Brismar +6 more
TL;DR: This study provides the first evidence that changes in DNA methylation of the IGFBP1 gene are associated with type 2 diabetes in Swedish men and suggests that increased IGF BP1 DNA methylations and decreased IGFBP-1 serum levels are features of type 2abetes with a short duration.
Journal ArticleDOI
Epigenetic analyses of the insulin-like growth factor binding protein 1 gene in type 1 diabetes and diabetic nephropathy
Tianwei Gu,Henrik Falhammar,Henrik Falhammar,Harvest F. Gu,Harvest F. Gu,Kerstin Brismar,Kerstin Brismar +6 more
TL;DR: This study shows for the first time that T1D patients had decreased DNA methylation levels in the IGFBP1 gene and further implies that increased circulating IGFBP-1 levels are associated with T 1D and DN.