F
François Alhenc-Gelas
Researcher at University of Paris
Publications - 6
Citations - 259
François Alhenc-Gelas is an academic researcher from University of Paris. The author has contributed to research in topics: Kidney disease & Renal function. The author has an hindex of 3, co-authored 6 publications receiving 246 citations. Previous affiliations of François Alhenc-Gelas include Paris Descartes University & French Institute of Health and Medical Research.
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Journal ArticleDOI
New susceptibility loci associated with kidney disease in type 1 diabetes.
Niina Sandholm,Niina Sandholm,Rany M. Salem,Rany M. Salem,Amy Jayne McKnight,Eoin P. Brennan,Carol Forsblom,Tamara Isakova,Gareth J. McKay,Winfred W. Williams,Denise M. Sadlier,Ville-Petteri Mäkinen,Ville-Petteri Mäkinen,Elizabeth Swan,Cameron D. Palmer,Cameron D. Palmer,Andrew P. Boright,Emma Ahlqvist,Harshal Deshmukh,Benjamin J. Keller,Huateng Huang,Aila J. Ahola,Emma Fagerholm,Daniel Gordin,Valma Harjutsalo,Valma Harjutsalo,Bing He,Outi Heikkilä,Kustaa Hietala,Janne P. Kytö,Päivi Lahermo,Markku Lehto,Raija Lithovius,Anne-May Österholm,Maija Parkkonen,Janne Pitkäniemi,Milla Rosengård-Bärlund,Markku Saraheimo,Cinzia Sarti,Jenny Söderlund,Aino Soro-Paavonen,Anna Syreeni,Lena M. Thorn,Heikki O. Tikkanen,Nina Tolonen,Karl Tryggvason,Jaakko Tuomilehto,Johan Wadén,Geoffrey V. Gill,Sarah L. Prior,Candace Guiducci,Daniel B. Mirel,Andrew M. Taylor,Andrew M. Taylor,S. Mohsen Hosseini,Hans-Henrik Parving,Hans-Henrik Parving,Peter Rossing,Peter Rossing,Lise Tarnow,Lise Tarnow,Claes Ladenvall,François Alhenc-Gelas,Pierre Lefebvre,Vincent Rigalleau,Ronan Roussel,David-Alexandre Trégouët,Anna Maestroni,Silvia Maestroni,Henrik Falhammar,Tianwei Gu,Anna Möllsten,D. Cimponeriu,Mihai Ioana,Maria Mota,Eugen Mota,Cristian Serafinceanu,Monica Stavarachi,Robert L. Hanson,Robert G. Nelson,Matthias Kretzler,Helen M. Colhoun,Nicolae Mircea Panduru,Harvest F. Gu,Kerstin Brismar,Gianpaolo Zerbini,Samy Hadjadj,Michel Marre,Michel Marre,Leif Groop,Maria Lajer,Shelley B. Bull,Daryl Waggott,Andrew D. Paterson,David A. Savage,Stephen C. Bain,Finian Martin,Joel N. Hirschhorn,Joel N. Hirschhorn,Catherine Godson,Jose C. Florez,Jose C. Florez,Per-Henrik Groop,Per-Henrik Groop,Alexander P. Maxwell,Alexander P. Maxwell +105 more
TL;DR: A meta-analysis of genome-wide association studies of T1D DN revealed association of two SNPs with ESRD in the AFF3 gene and an intergenic SNP on chromosome 15q26 between the genes RGMA and MCTP2, which represent new signals in the pathogenesis of DN.
Journal ArticleDOI
Plasma Adrenomedullin and Allelic Variation in the ADM Gene and Kidney Disease in People With Type 2 Diabetes
Gilberto Velho,Stéphanie Ragot,Stéphanie Ragot,Kamel Mohammedi,Elise Gand,M. Fraty,Frédéric Fumeron,Frédéric Fumeron,Pierre-Jean Saulnier,Pierre-Jean Saulnier,Naima Bellili-Muñoz,Nadine Bouby,Nadine Bouby,Nadine Bouby,Louis Potier,Louis Potier,François Alhenc-Gelas,François Alhenc-Gelas,François Alhenc-Gelas,Michel Marre,Michel Marre,Samy Hadjadj,Ronan Roussel,Ronan Roussel +23 more
TL;DR: Results are consistent with the hypothesis of a reactive rise ofADM in diabetic nephropathy, blunted in risk alleles carriers, and with a nephroprotective effect of ADM.
Journal ArticleDOI
Kinins and Kinin Receptors in Cardiovascular and Renal Diseases.
Jean-Pierre Girolami,Nadine Bouby,Nadine Bouby,Christine Richer-Giudicelli,Christine Richer-Giudicelli,François Alhenc-Gelas,François Alhenc-Gelas +6 more
TL;DR: In this paper, the physiological role of the kallikrein-kinin system in arteries, heart and kidney and the consequences of kalli-rein and kinin actions in diseases affecting these organs, especially ischemic and diabetic diseases are discussed.
Journal ArticleDOI
ACE I/D Polymorphism, Plasma ACE Levels, and Long-term Kidney Outcomes or All-Cause Death in Patients With Type 1 Diabetes.
Yawa Abouleka,Kamel Mohammedi,Charlyne Carpentier,Séverine Dubois,Pierre Gourdy,Jean-François Gautier,Ronan Roussel,André Scheen,François Alhenc-Gelas,Samy Hadjadj,Gilberto Velho,Michel Marre +11 more
TL;DR: In this article, the deletion (D) allele of the ACE insertion/deletion (I/D) polymorphism is associated with an increased risk of major kidney events and all-cause death in patients with long-standing type 1 diabetes.