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Larry Rand
Researcher at University of California, San Francisco
Publications - Â 114
Citations - Â 26743
Larry Rand is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Pregnancy & Gestational age. The author has an hindex of 32, co-authored 105 publications receiving 25047 citations. Previous affiliations of Larry Rand include Joslin Diabetes Center & Harvard University.
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Journal ArticleDOI
The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus.
Diabetes Control,David M. Nathan,Saul M. Genuth,John M. Lachin,Patricia A. Cleary,O Crofford,Matthew M. Davis,Larry Rand,Carolyn Siebert +8 more
TL;DR: Intensive therapy effectively delays the onset and slows the progression of diabetic retinopathy, nephropathy, and neuropathy in patients with IDDM.
Journal ArticleDOI
Magnitude and determinants of coronary artery disease in juvenile-onset, insulin-dependent diabetes mellitus.
Andrzej S. Krolewski,E J Kosinski,J H Warram,O S Leland,E J Busick,Asmal Ac,Larry Rand,A R Christlieb,R F Bradley,C R Kahn +9 more
TL;DR: The pattern suggests that juvenile-onset diabetes and its renal complications are modifiers of the natural history of atherosclerosis in that although they profoundly accelerate progression of early atherosclerotic lesions to very severe CAD, they may not contribute to initiation of Atherosclerosis.
Journal ArticleDOI
Predisposition to hypertension and susceptibility to renal disease in insulin-dependent diabetes mellitus.
Andrzej S. Krolewski,Mitzy Canessa,James H. Warram,Lori M.B. Laffel,A R Christlieb,W. C. Knowler,Larry Rand +6 more
TL;DR: The risk of renal disease in patients with juvenile-onset insulin-dependent diabetes is associated with a genetic predisposition to hypertension, and this appears to increase susceptibility for renal disease principally in Patients with poor glycemic control.
Journal ArticleDOI
Epidemiologic Approach to the Etiology of Type I Diabetes Mellitus and Its Complications
TL;DR: The pancreas is destroyed through two etiologically distinct routes, and type I diabetes is the result of immunologically mediated destruction of the pancreatic beta cells, and usually requires replacement beta cells.
Journal ArticleDOI
Prolonged effect of intensive therapy on the risk of retinopathy complications in patients with type 1 diabetes mellitus: 10 years after the diabetes control and complications trial
Neil H. White,Wanjie Sun,Patricia A. Cleary,Ronald P. Danis,Matthew D. Davis,Dean P. Hainsworth,Larry D. Hubbard,John M. Lachin,David M. Nathan,Oscar B. Crofford,Jill P. Crandall,M. Phillips,M. Reid,J. Brown-Friday,Samuel S. Engel,J. Sheindlin,H. Martinez,H. Shamoon,H. Engel,William Dahms,M. Palmert,Rose Gubitosi-Klug,L. Mayer,S. Pendegras,H. Zegarra,David G. Miller,Lawrence J. Singerman,Sheila Smith-Brewer,M. Novak,P. Gaston,Saul Genuth,David J. Brillon,M. E. Lackaye,V. Reppucci,Thomas C. Lee,Murk-Hein Heinemann,Fred W. Whitehouse,M. McLellan,Davida F. Kruger,J. D. Carey,E. Angus,M. Croswell,A. Galpirn,Richard M. Bergenstal,M. Johnson,M. Spencer,K. Morgan,D. Etzwiler,David M. Kendall,D. Noller,Alan M. Jacobson,E. Golden,R. Beaser,Om P. Ganda,O. Hamdy,J. Rosenzweig,H. Wolpert,P. G. Sharuk,Paul G. Arrigg,A. Burwood,Larry Rand,Mary E. Larkin,John E. Godine,D. Moore,Enrico Cagliero,P. Lou,S. Fritz,G. Ziegler,John M. Pach,R. Colligan,Maria F. Lopes-Virella,John A. Colwell,Kathie L. Hermayer,M. Brabham,J. Soule,A. Blevins,J. Parker,David A. Lee,P. Lindsey,M. Bracey,K. Lee,M. Nutaitis,A. Farr,S. Elsing,T. Thompson,J. Selby,Timothy J. Lyons,S. Yacoub-Wasef,M. Szpiech,D. Wood,Ronald K. Mayfield,Mark E. Molitch,B. Schaefer,Lee M. Jampol,Alice T. Lyon,Manjot K. Gill,Z. Strugula,L. Kaminski,Jonathan Shankle,P. Astlesford,D. Blackburn,Senda Ajroud-Driss,O. Stone,C. West,Inger Burnett-Zeigler,Orville G. Kolterman,Gayle M. Lorenzi,Michael H. Goldbaum,K. Harvey,Henry Ferreyra,William I. Sivitz,Margaret L. Bayless,Thomas A. Weingeist,Edwin M. Stone,H. Culver Boldt,K. Gehres,Stephen R. Russell,J. Bayless,J. Kramer,J. Long,R. Zeither,M. Hebdon,Thomas Donner,S. Johnsonbaugh,J. Gordon,Ramzi K. Hemady,A. Kowarski,D. Ostrowski,Scott M. Steidl,B. Jones,D. Counts,William H. Herman,Catherine L. Martin,Rodica Pop-Busui,Andrew K. Vine,Susan G. Elner,Eva L. Feldman,James W. Albers,Douglas A. Greene,Martin J. Stevens,John P. Bantle,B. Rogness,Timothy W. Olsen,E. Steuer,Pamela Rath,S. Hitt,J. Giangiacom,David E. Goldstein,David S. Schade,J. L. Canady,J. M. Schluter,Arup Das,D. Hornbeck,Sharon B. Schwartz,P. A. Bourne,Barbara J. Maschak-Carey,L. Baker,S. Braunstein,Alexander J. Brucker,Trevor J. Orchard,N. Silvers,Christopher M. Ryan,Thomas J. Songer,Bernard H. Doft,Shelly Olson,Robert Bergren,Louis A. Lobes,P. Paczan Rath,D. J. Becker,Allan L. Drash,Anthony D. Morrison,J. Vaccaro-Kish,M. L. Bernal,John I. Malone,Peter R. Pavan,N. Grove,M. N. Iyer,A. F. Burrows,E. A. Tanaka,R. Gstalder,Samuel Dagogo-Jack,C. Wigley,H. Ricks,Abbas E. Kitabchi,M. B. Murphy,S. Moser,D. Meyer,A. Iannacone,Edward Chaum,S. Yoser,Michael Bryer-Ash,S. Schussler,Helen Lambeth,Philip Raskin,S. Strowig,R. Ufret,Yu-Guang He,A. Edwards,J. Alappatt,C. Wilson,S. Park,B. Zinman,Annette Barnie,S. MacLean,R. Devenyi,Mark S. Mandelcorn,M. Brent,S. Rogers,A. Gordon,Jerry P. Palmer,S. Catton,John D. Brunzell,J. Ginsberg,James L. Kinyoun,L. Van Ottingham,John Dupre,J. Harth,David A. Nicolle,C. Canny,M. May,Janie Lipps,Anupam Agarwal,T. Adkins,L. Survant,Rodney A. Lorenz,Stephen S. Feman,Lucy A. Levandoski,Isaac Boniuk,G. Grand,Matthew A. Thomas,Dean B. Burgess,Daniel P. Joseph,Kevin J. Blinder,Gaurav K. Shah,Julio V. Santiago,William V. Tamborlane,Patricia Gatcomb,K. Stoessel,K. Taylor,R. Trail,J. Quin,D. Kenny,Jye-Yu C. Backlund,Brandy N. Rutledge,Barbara H. Waberski,K. Klumpp,K. Chan,Lisa Diminick,D. Rosenberg,B. Petty,A. Determan,C. Williams,L. Dews,M. Hawkins,C. Cowie,J. Fradkin,C. Siebert,R. Eastman,P. Geithman,L. Kastorff,Michael W. Neider,D. Badal,Barbara Esser,K. Miner,Hugh D. Wabers,Kathy Glander,Jeffrey M. Joyce,Nancy L. Robinson,C. Hurtenbach,C. Hannon,Michael W. Steffes,Jean M. Bucksa,Blanche M. Chavers,Daniel H. O'Leary,L. Funk,Joseph F. Polak,Anita Harrington,Richard S. Crow,B. Gloeb,S. Thomas,C. O'Donnell,Ronald J. Prineas,Charles Campbell,D. Sandstrom,T. Williams,M. Geckle,E. Cupelli,F. Thoma,B. Burzuk,T. Woodfill,P. Low,C. Sommer,K. Nickander,Robert Detrano,N. Wong,M. Fox,L. Kim,R. Oudiz,Gordon C. Weir,C. Clark,R. D'Agostino,M. Espeland,Barbara E. K. Klein,T. Manolio,D. Singer,M. Stern,W. T. Garvey,Alicia J. Jenkins,Ronald Klein,Gabriel Virella,Ayad A. Jaffa,Daniel T. Lackland,Daniel L. McGee,D. Zheng,Andrew M. Paterson,Andrew P. Boright,Shelley B. Bull,L. Sun,S. Scherer,John E. Hokanson,Santica M. Marcovina,Jonathan Q. Purnell,Shalamar D. Sibley,Samir S. Deeb,Kate Edwards +324 more
TL;DR: The persistent difference in diabetic retinopathy between former intensive and conventional therapy ("metabolic memory") continues for at least 10 years but may be waning.