L
Laura K. Hummers
Researcher at Johns Hopkins University School of Medicine
Publications - 146
Citations - 8269
Laura K. Hummers is an academic researcher from Johns Hopkins University School of Medicine. The author has contributed to research in topics: Scleroderma & Pulmonary hypertension. The author has an hindex of 45, co-authored 129 publications receiving 7015 citations. Previous affiliations of Laura K. Hummers include Thomas Jefferson University & Johns Hopkins University.
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Journal ArticleDOI
Causes and risk factors for death in systemic sclerosis: a study from the EULAR Scleroderma Trials and Research (EUSTAR) database
A Tyndall,Bettina Bannert,Madelon C. Vonk,Paolo Airò,Franco Cozzi,Patricia Carreira,Dominique Farge Bancel,Yannick Allanore,Ulf Müller-Ladner,Oliver Distler,Florenzo Iannone,Raffaele Pellerito,Margarita Pileckyte,I. Miniati,L. Ananieva,Alexandra Balbir Gurman,Nemanja Damjanov,Adelheid Mueller,Gabriele Valentini,Gabriela Riemekasten,Mohammed Tikly,Laura K. Hummers,Maria João Henriques,Paola Caramaschi,Agneta Scheja,Blaz Rozman,Evelien Ton,Gábor Kumánovics,Bernard Coleiro,Eva Feierl,Gabriella Szücs,Carlos Alberto Von Mühlen,Valeria Riccieri,Srdan Novak,Carlo Chizzolini,Anna Kotulska,Christopher P. Denton,Paulo C. Coelho,Ina Kötter,Ismail Simsek,Paloma García de la Peña Lefebvre,Eric Hachulla,James R. Seibold,Simona Rednic,Jiri Stork,Jadranka Morović-Vergles,Ulrich A. Walker +46 more
TL;DR: Disease-related causes, in particular pulmonary fibrosis, PAH and cardiac causes, accounted for the majority of deaths in SSc.
Journal ArticleDOI
Proposed diagnostic criteria and nosology of acute transverse myelitis
G. Barnes,S. Benjamin,J. D. Bowen,N. Cutter,B. J. De Lateur,W. D. Dietrich,M. M. Dowling,J. W. Griffin,Laura K. Hummers,David N. Irani,Philippe G. Jorens,Adam I. Kaplin,J. D. Katz,Douglas A. Kerr,Chitra Krishnan,C. E. Levy,C. Lucchinetti,D. J. Lynn,R. N. Mandler,Justin C. McArthur,John W. McDonald,L. Morrison,Carlos Pardo-Villamizar,Frank S. Pidcock,R. Ransohoff,Karen L. Roos,M. K. Trovato,Timothy Vollmer,S. T. Wegener,Brian G. Weinshenker,Dean M. Wingerchuk +30 more
TL;DR: A set of uniform diagnostic criteria and nosology for ATM is proposed to avoid the confusion that inevitably results when investigators use differing criteria, and a framework is suggested for evaluation of individuals presenting with signs and symptoms of ATM.
Journal ArticleDOI
Genome-wide association study of systemic sclerosis identifies CD247 as a new susceptibility locus
Timothy R D J Radstake,Olga Y. Gorlova,Blanca Rueda,Jose Ezequiel Martin,Behrooz Z. Alizadeh,Rogelio Palomino-Morales,Marieke J H Coenen,Madelon C. Vonk,Alexandre E. Voskuyl,Annemie J. Schuerwegh,Jasper C A Broen,Piet L. C. M. van Riel,Ruben van 't Slot,Annet Italiaander,Roel A. Ophoff,Roel A. Ophoff,Gabriela Riemekasten,Nico Hunzelmann,Carmen P. Simeon,Norberto Ortego-Centeno,Miguel A. Gonzalez-Gay,María Francisca González-Escribano,Paolo Airò,Jaap M van Laar,Ariane L. Herrick,Jane Worthington,Roger Hesselstrand,Vanessa Smith,Filip De Keyser,Fredric Houssiau,Meng May Chee,Rajan Madhok,Paul G. Shiels,Rene Westhovens,Alexander Kreuter,Hans P. Kiener,Elfride De Baere,Torsten Witte,Leonid Padykov,Lars Klareskog,Lorenzo Beretta,Rafaella Scorza,Benedicte A. Lie,Anna Maria Hoffmann-Vold,Patricia Carreira,John Varga,Monique Hinchcliff,Peter K. Gregersen,Annette Lee,Jun Ying,Younghun Han,Shih-Feng Weng,Christopher I. Amos,Fredrick M. Wigley,Laura K. Hummers,J. Lee Nelson,Sandeep K. Agarwal,Shervin Assassi,Pravitt Gourh,Filemon K. Tan,Bobby P. C. Koeleman,Frank C. Arnett,Javier Martín,Maureen D. Mayes +63 more
TL;DR: The first genome-wide association study in a population of European ancestry including a total of 2,296 individuals with SSc and 5,171 controls identified a new susceptibility locus for systemic sclerosis at CD247 (1q22–23, rs2056626).
Journal ArticleDOI
Clinical differences between idiopathic and scleroderma-related pulmonary hypertension
Micah R. Fisher,Stephen C. Mathai,Hunter C. Champion,Reda E. Girgis,Traci Housten-Harris,Laura K. Hummers,Jerry A. Krishnan,Fredrick M. Wigley,Paul M. Hassoun +8 more
TL;DR: There are significant clinical and survival differences between IPAH and PAH-Scl, and the presence of left heart disease, although more common in PAH, was not predictive of the higher mortality in these patients.
Journal ArticleDOI
Survival in pulmonary hypertension associated with the scleroderma spectrum of diseases: impact of interstitial lung disease.
Stephen C. Mathai,Laura K. Hummers,Hunter C. Champion,Fredrick M. Wigley,Ari L. Zaiman,Paul M. Hassoun,Reda E. Girgis +6 more
TL;DR: While therapy may be associated with improved survival in PAH compared with historical controls, the prognosis for patients with ILD-associated PH is particularly grim and survival in SSc complicated by PH remains poor despite currently available treatment options.