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Simona Rednic
Researcher at Iuliu Hațieganu University of Medicine and Pharmacy
Publications - 135
Citations - 4316
Simona Rednic is an academic researcher from Iuliu Hațieganu University of Medicine and Pharmacy. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 24, co-authored 102 publications receiving 3231 citations. Previous affiliations of Simona Rednic include University of Florence.
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Journal ArticleDOI
Causes and risk factors for death in systemic sclerosis: a study from the EULAR Scleroderma Trials and Research (EUSTAR) database
A Tyndall,Bettina Bannert,Madelon C. Vonk,Paolo Airò,Franco Cozzi,Patricia Carreira,Dominique Farge Bancel,Yannick Allanore,Ulf Müller-Ladner,Oliver Distler,Florenzo Iannone,Raffaele Pellerito,Margarita Pileckyte,I. Miniati,L. Ananieva,Alexandra Balbir Gurman,Nemanja Damjanov,Adelheid Mueller,Gabriele Valentini,Gabriela Riemekasten,Mohammed Tikly,Laura K. Hummers,Maria João Henriques,Paola Caramaschi,Agneta Scheja,Blaz Rozman,Evelien Ton,Gábor Kumánovics,Bernard Coleiro,Eva Feierl,Gabriella Szücs,Carlos Alberto Von Mühlen,Valeria Riccieri,Srdan Novak,Carlo Chizzolini,Anna Kotulska,Christopher P. Denton,Paulo C. Coelho,Ina Kötter,Ismail Simsek,Paloma García de la Peña Lefebvre,Eric Hachulla,James R. Seibold,Simona Rednic,Jiri Stork,Jadranka Morović-Vergles,Ulrich A. Walker +46 more
TL;DR: Disease-related causes, in particular pulmonary fibrosis, PAH and cardiac causes, accounted for the majority of deaths in SSc.
Journal ArticleDOI
Mapping and predicting mortality from systemic sclerosis
Muriel Elhai,Christophe Meune,Marouane Boubaya,Jérôme Avouac,Eric Hachulla,Alexandra Balbir-Gurman,Gabriela Riemekasten,Paolo Airò,Beatriz Joven,Serena Vettori,Franco Cozzi,Susanne Ullman,László Czirják,Mohammed Tikly,Ulf Müller-Ladner,Paola Caramaschi,Oliver Distler,Florenzo Iannone,L. Ananieva,Roger Hesselstrand,R. Becvar,Armando Gabrielli,Nemanja Damjanov,Maria João Salvador,Valeria Riccieri,Carina Mihai,Gabriella Szücs,Ulrich A Walker,Nicolas Hunzelmann,Duska Martinovic,Vanessa Smith,Carolina de Souza Müller,Carlomaurizio Montecucco,Daniela Opris,Francesca Ingegnoli,Panayiotis G. Vlachoyiannopoulos,Bojana Stamenkovic,Edoardo Rosato,Stefan Heitmann,Jörg H W Distler,Thierry Zenone,Matthias Seidel,Alessandra Vacca,Ellen De Langhe,Srdan Novak,Maurizio Cutolo,Luc Mouthon,Jörg Henes,Carlo Chizzolini,Carlos Alberto Von Mühlen,Kamal Solanki,Simona Rednic,Lisa K. Stamp,Branimir Anić,Branimir Anić,Vera Ortiz Santamaria,Maria De Santis,Sule Yavuz,Walter Alberto Sifuentes-Giraldo,Emmanuel Chatelus,Jiri Stork,Jacob M van Laar,Esthela Loyo,Paloma García de la Peña Lefebvre,Kilian Eyerich,Vanesa Cosentino,Juan José Alegre-Sancho,Otylia Kowal-Bielecka,Grégoire Rey,Marco Matucci-Cerinic,Yannick Allanore +70 more
TL;DR: Combining two complementary and detailed databases enabled the collection of an unprecedented 3700 deaths, revealing the major contribution of the cardiopulmonary system to SSc mortality.
Journal ArticleDOI
Effects and safety of rituximab in systemic sclerosis: an analysis from the European Scleroderma Trial and Research (EUSTAR) group
Suzana Jordan,Jörg H W Distler,Britta Maurer,Dörte Huscher,Jacob M van Laar,Yannick Allanore,Oliver Distler,Tore K Kvien,Paolo Airò,Juan José Alegre Sancho,Lidia Ananjeva,Codrina Michaela Ancuta,Martin Aringer,Alexandra Balbir-Gurman,Francesco Paolo Cantatore,Paola Caramaschi,Emmanuel Chatelus,Veronica Codullo,Dominique Farge-Bancel,Rosario Foti,Armando Gabrielli,Jörg Henes,I. Herrgott,Florenzo Iannone,Francesca Ingegnoli,Esthela Loyo,Marco Matucci-Cerinic,Walid Ahmed Abdel Atty Mohamed,Ulf Müller-Ladner,Øyvind Palm,Sergiu Popa,Gabriela Riemekasten,Simona Rednic,Edoardo Rosato,M. Saracco,Agneta Scheja,Vanessa Smith,Carina Mihai,Gabriela Szucs,Matija Tomšič,Gabriele Valentini,Ulrich A. Walker,Rene Westhovens,Sule Yavuz,Thierry Zenone +44 more
TL;DR: The comparison of RTX treated versus untreated matched-control SSc patients from the EUSTAR cohort demonstrated improvement of skin fibrosis and prevention of worsening lung fibrosis, supporting the therapeutic concept of B cell inhibition in SSc.
Journal ArticleDOI
Preliminary criteria for the very early diagnosis of systemic sclerosis: results of a Delphi Consensus Study from EULAR Scleroderma Trials and Research Group
Jérôme Avouac,Jaap Fransen,Ulrich A. Walker,Valeria Riccieri,Vanessa Smith,Carolina de Souza Müller,I. Miniati,Ingo H. Tarner,S. Bellando Randone,Maurizio Cutolo,Yannick Allanore,Oliver Distler,Gabriele Valentini,L. Czirják,Ulf Müller-Ladner,Daniel E. Furst,A Tyndall,Marco Matucci-Cerinic,F De Keyser,Alberto Sulli,Carmen Pizzorni,Britta Maurer,Stanislaw Sierakowsky,Otylia Kowal-Bielecka,P. Coelho,G. Riemekasten,Simona Rednic,Ileana Nicoara,Roberto Caporali,Jiri Stork,Murat Inanc,Patricia Carreira,Srdan Novak,Cecília Varjú,Carlo Chizzolini,Camillo Ribi,Eugeniusz J. Kucharz,AT Kotulska,Małgorzata Widuchowska,Jutta G Richter,A. Sipek-Dolnicar,Blaž Rozman,Armando Gabrielli,Gianluca Moroncini,Dominique Farge,C. Durant,Hans P. Kiener,E. Rath,Paolo Airò,Frank A. Wollheim,Nicolas Hunzelmann,Stefano Bombardieri,A. Della Rossa,Laura Bazzichi,Raffaele Pellerito,M. Saracco,Christopher P. Denton,Madelon C. Vonk,F.H.J. van den Hoogen,Nemanja Damjanov,Ina Kötter,Stefan Heitmann,Matthias Seidel,Paul Hasler,J.M. van Laar,Maria João Salvador,J.A. Pereira da Silva,Søren Jacobsen,Margitta Worm,Annegret Kuhn,Tatiana Nevskaya,Evgeny Nasonov,Raffaella Scorza,Henrik Nielsen,Richard M. Silver,Eric Hachulla,D. Launay,Guido Valesini,Ruxandra Ionescu,Daniela Opris,N. Del Papa,Wanda Maglione,D. Comina,G. Udrea,Coziana Ciurtin,R. Ionitescu,C. Mihai,Cord Sunderkötter,Jae Bum Jun,Chris T. Derk,S. Alhasani,L. Alhajjar,Evelien Ton,James R. Seibold,Peter Nash,Luc Mouthon,C. A. Von Mühlen,Brigitte Krummel-Lorenz,P. Eilbacher,Rene Westhovens,E. De Langhe,Miroslav Mayer,Branimir Anić,M. Baresic,F. Stoeckl,Maria Uprus,S. Popa,M. Buslau,B. Granel,Thierry Zenone,Alessandro Mathieu,Alessandra Vacca,Paolo Amerio,T. Tourinho,L. Lonzetti,M. Lemos Lopes,R. E. de Souza,D. Vealex,Paola Caramaschi,Alexandra Balbir-Gurman,Y. Braun,Susanne Ullman,Magdalena Szmyrka-Kaczmarek,Ewa Morgiel,Marie Vanthuyne,M. Meurer,P. Rehberger,Percival D. Sampaio-Barros +127 more
TL;DR: A core set of preliminary items considered as important for the very early diagnosis of systemic sclerosis were identified in a Delphi exercise among 110 experts in the field of SSc.
Journal ArticleDOI
Tocilizumab in systemic sclerosis: a randomised, double-blind, placebo-controlled, phase 3 trial.
Dinesh Khanna,Celia J. F. Lin,Daniel E. Furst,Jonathan G. Goldin,Grace Kim,Masataka Kuwana,Yannick Allanore,Marco Matucci-Cerinic,Oliver Distler,Yoshihito Shima,Jacob M van Laar,Helen Spotswood,Bridget Wagner,Jeffrey Siegel,Angelika Jahreis,Christopher P. Denton,Eleonora Lucero,Bernardo A. Pons-Estel,Mariano Rivero,Guillermo Tate,Vanessa Smith,Ellen De Langhe,Rasho Rashkov,Anastas Batalov,Ivan Goranov,Rumen Stoilov,James V. Dunne,Sindhu R. Johnson,Janet E. Pope,Dušanka Martinović Kaliterna,Mette Mogensen,Anne Braae Olesen,Joerg Henes,Ulf Müller-Ladner,Gabriela Riemekasten,Alla Skapenko,Panayiotis G. Vlachoyiannopoulos,Emese Kiss,Tünde Minier,Lorenzo Beretta,Elisa Gremese,Gabriele Valentini,Yoshihide Asano,Tatsuya Atsumi,Hironobu Ihn,Tomonori Ishii,Osamu Ishikawa,Hiroki Takahashi,Kazuhiko Takehara,Yoshiya Tanaka,Yoshioki Yamasaki,Loreta Bukauskiene,Irena Butrimiene,Gabriel Medrano Ramirez,Cesar Ramos-Remus,Tatiana Sofia Rodriguez Reyna,Jeska K de Vries-Bouwstra,Bogdan Batko,Sławomir Jeka,Eugeniusz J. Kucharz,Maria Majdan,Marzena Olesińska,Zaneta Smolenska,Jose Alves,Maria José Santos,C. Mihai,Simona Rednic,Ivan Castellvi Barranco,Francisco Javier Lopez Longo,Carmen Simeon Aznar,Patricia Carreira,Ulrich A. Walker,Emma Derrett-Smith,Bridget Griffiths,Neil McKay,Jacob Aelion,Michael S. Borofsky,Roy Fleischmann,Joseph Z. Forstot,Suzanne Kafaja,M. Faisal Khan,Michael D. Kohen,Richard J. Martin,Fabian Mendoza-Ballesteros,Alireza Nami,Shirley Pang,Grissel Rios,Robert W. Simms,Keith M. Sullivan,Virginia D. Steen +89 more
TL;DR: Findings for the secondary endpoint of FVC% predicted indicate that tocilizumab might preserve lung function in people with early SSc-ILD and elevated acute-phase reactants.