Lei Wei

TL;DR: It is demonstrated that miR-1 expression protects against osteoarthritis-induced cartilage damage and gene expression by inhibiting Ihh signaling and that the protein expression of Ihh, Col10, and MMP-13 was significantly higher in the joint tissues of the non-tamoxifen + ACLT group than in those of the tamoxifens + ACLS group.

TL;DR: Behaviour closely analogous to that of the insulin receptor tail peptide was observed during changes in phosphorylation of the intact insulin receptor kinase domain, suggesting that the electrostatic dissemination effects seen for the isolated peptide are retained by the peptide sequence in the context of the much larger protein.

TL;DR: CTS alters chondrocytes gene expression in association with the relocation of HDAC4 induced by CTS, and there was no chondROcyte dead detected in this study in response to CTS.

TL;DR: Results indicated that SSb2 may be a potential antitumor drug for the treatment of breast cancer, which acts by suppressing proliferation and migration by downregulating the STAT3 signalling pathway and inhibiting the expression of VASP, MMP2 and MMP9 expression.

TL;DR: The clinical characteristics of dialysis patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection are sought to describe and deaths from all causes excluding COVID-19 during the epidemic cannot be ignored.