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Lei Yan

Researcher at Nanjing Medical University

Publications -  6
Citations -  33

Lei Yan is an academic researcher from Nanjing Medical University. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 2, co-authored 2 publications receiving 16 citations.

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Journal ArticleDOI

Small P values may not yield robust findings: an example using REST-meta-PD

Xi Ze Jia, +80 more
Posted ContentDOI

Small effect size leads to reproducibility failure in resting-state fMRI studies

Xi-Ze Jia, +75 more
- 20 Mar 2018 - 
TL;DR: To achieve high reproducibility through meta-analysis, the neuroimaging research field should share raw data or, at minimum, provide un-thresholded statistical images, as well as for another widely used RS-fMRI metric namely seed-based functional connectivity.
Journal ArticleDOI

Aberrant inter-network functional connectivity in drug-naive Parkinson’s disease patients with tremor dominant and postural instability and gait difficulty

TL;DR: In this article , the authors investigated the alterations of intra-and inter-network functional connectivity (FC) in drug-naive PD patients with different motor subtypes, including tremor dominant (TD) and postural instability and gait disorder (PIGD).
Journal ArticleDOI

Levodopa improved different motor symptoms in patients with Parkinson's disease by reducing the functional connectivity of specific thalamic subregions.

TL;DR: In this article , the authors explored the mechanism by which levodopa modulates the functional connectivity (FC) in the subregions of the thalamus and the relationship between the changed FC and the improvement of motor symptoms in Parkinson's disease patients.
Journal ArticleDOI

Altered functional connectivity of the primary motor cortex in tremor dominant and postural instability gait difficulty subtypes of early drug-naive Parkinson’s disease patients

TL;DR: In this paper , the functional connectivity of the primary motor cortex (M1) subregions varied between the PD and PIGD subtypes, and the results showed that early PD patients share some common injury and compensatory mechanisms.