L
Liesbet Henckaerts
Researcher at Katholieke Universiteit Leuven
Publications - 74
Citations - 7026
Liesbet Henckaerts is an academic researcher from Katholieke Universiteit Leuven. The author has contributed to research in topics: Inflammatory bowel disease & Primary sclerosing cholangitis. The author has an hindex of 28, co-authored 69 publications receiving 5450 citations. Previous affiliations of Liesbet Henckaerts include Catholic University of Leuven & University of Antwerp.
Papers
More filters
Journal ArticleDOI
Prediction models for diagnosis and prognosis of covid-19: systematic review and critical appraisal
Laure Wynants,Laure Wynants,Ben Van Calster,Ben Van Calster,Gary S. Collins,Gary S. Collins,Richard D Riley,Georg Heinze,Ewoud Schuit,Marc J.M. Bonten,Darren Dahly,Johanna A A G Damen,Thomas P. A. Debray,Valentijn M.T. de Jong,Maarten De Vos,Paula Dhiman,Paula Dhiman,Maria C Haller,Michael O. Harhay,Liesbet Henckaerts,Pauline Heus,Michael Kammer,Nina Kreuzberger,Anna Lohmann,Kim Luijken,Jie Ma,Glen P. Martin,David J. McLernon,Constanza L Andaur Navarro,Johannes B. Reitsma,Jamie C. Sergeant,Chunhu Shi,Nicole Skoetz,Luc J.M. Smits,Kym I E Snell,Matthew Sperrin,René Spijker,René Spijker,Ewout W. Steyerberg,Toshihiko Takada,Ioanna Tzoulaki,Ioanna Tzoulaki,Sander M. J. van Kuijk,Bas C T van Bussel,Bas C T van Bussel,Iwan C. C. van der Horst,Florien S. van Royen,Jan Y Verbakel,Jan Y Verbakel,Christine Wallisch,Christine Wallisch,Jack Wilkinson,Robert Wolff,Lotty Hooft,Karel G.M. Moons,Maarten van Smeden +55 more
TL;DR: Proposed models for covid-19 are poorly reported, at high risk of bias, and their reported performance is probably optimistic, according to a review of published and preprint reports.
Journal ArticleDOI
Population-level analysis of gut microbiome variation
Gwen Falony,Marie Joossens,Marie Joossens,Sara Vieira-Silva,Jun Wang,Youssef Darzi,Youssef Darzi,Karoline Faust,Karoline Faust,Alexander Kurilshikov,Marc Jan Bonder,Mireia Valles-Colomer,Doris Vandeputte,Doris Vandeputte,Raul Y. Tito,Raul Y. Tito,Samuel Chaffron,Samuel Chaffron,Leen Rymenans,Leen Rymenans,Chloë Verspecht,Lise De Sutter,Lise De Sutter,Gipsi Lima-Mendez,Kevin D'hoe,Kevin D'hoe,Karl Jonckheere,Karl Jonckheere,Daniel Homola,Daniel Homola,Roberto Garcia,Roberto Garcia,Ettje F. Tigchelaar,Linda Eeckhaudt,Linda Eeckhaudt,Jingyuan Fu,Liesbet Henckaerts,Alexandra Zhernakova,Cisca Wijmenga,Jeroen Raes,Jeroen Raes +40 more
TL;DR: Stool consistency showed the largest effect size, whereas medication explained largest total variance and interacted with other covariate-microbiota associations, and proposed disease marker genera associated to host covariates were found associated to microbiota compositional variation with a 92% replication rate.
Journal ArticleDOI
Long-term safety of infliximab for the treatment of inflammatory bowel disease: a single-centre cohort study
Herma H. Fidder,F. Schnitzler,Marc Ferrante,Maja Noman,Konstantinos Katsanos,Siegfried Segaert,Liesbet Henckaerts,G. Van Assche,Severine Vermeire,Paul Rutgeerts +9 more
TL;DR: Long-term infliximab treatment had a good overall safety profile in the patient cohort studied, with no difference between the two groups in mortality, malignancies and infection rate.
Journal ArticleDOI
Genome-Wide Association Analysis in Primary Sclerosing Cholangitis
Tom H. Karlsen,Andre Franke,Espen Melum,Arthur Kaser,Johannes R. Hov,Tobias Balschun,Benedicte A. Lie,Annika Bergquist,Christoph Schramm,Tobias J. Weismüller,Daniel Gotthardt,Christian Rust,Eva E. R. Philipp,Teresa Fritz,Liesbet Henckaerts,Rinse K. Weersma,Pieter C. F. Stokkers,Cyriel Y. Ponsioen,Cisca Wijmenga,Martina Sterneck,Michael Nothnagel,Jochen Hampe,Andreas Teufel,Heiko Runz,Philip Rosenstiel,Adolf Stiehl,Severine Vermeire,Ulrich Beuers,Michael P. Manns,Erik Schrumpf,Kirsten Muri Boberg,Stefan Schreiber +31 more
TL;DR: Strong HLA associations and a subset of genes involved in bile homeostasis and other inflammatory conditions constitute key components of the genetic architecture of PSC.
Journal ArticleDOI
New serological markers in inflammatory bowel disease are associated with complicated disease behaviour
Marc Ferrante,Liesbet Henckaerts,Marie Joossens,Marie J. Pierik,Sofie Joossens,Nir Dotan,Gary L. Norman,Rom T. Altstock,Kristel Van Steen,Paul Rutgeerts,Gert Van Assche,Severine Vermeire +11 more
TL;DR: The number and magnitude of immune responses to different microbial antigens were shown to be associated with the severity of the disease and the predictive role of serological markers are necessary.