L
Linda Karen Hughes
Researcher at University of Warwick
Publications - 4
Citations - 1238
Linda Karen Hughes is an academic researcher from University of Warwick. The author has contributed to research in topics: Hyaloperonospora arabidopsidis & Arabidopsis. The author has an hindex of 3, co-authored 4 publications receiving 1104 citations.
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Journal ArticleDOI
High-Resolution Temporal Profiling of Transcripts during Arabidopsis Leaf Senescence Reveals a Distinct Chronology of Processes and Regulation
Emily Breeze,Elizabeth Harrison,Stuart McHattie,Linda Karen Hughes,Richard Hickman,Claire Hill,Steven J. Kiddle,Youn-Sung Kim,Christopher A. Penfold,Dafyd J. Jenkins,Cunjin Zhang,Karl Morris,Carol E. Jenner,Stephen D. Jackson,Brian Thomas,Alex Tabrett,Roxane Legaie,Jonathan D. Moore,David L. Wild,Sascha Ott,David A. Rand,Jim Beynon,Katherine J. Denby,Andrew Mead,Vicky Buchanan-Wollaston +24 more
TL;DR: Analysis of motif enrichment, as well as comparison of transcription factor families showing altered expression over the time course, identify clear groups of TFs active at different stages of leaf development and senescence, which will underpin the development of network models to elucidate the process of Senescence.
Journal ArticleDOI
Signatures of adaptation to obligate biotrophy in the Hyaloperonospora arabidopsidis genome
Laura Baxter,Sucheta Tripathy,Naveed Ishaque,Nico Boot,Adriana Cabral,Eric Kemen,Marco Thines,Marco Thines,Audrey M. V. Ah-Fong,Ryan G. Anderson,Wole Badejoko,Peter D. Bittner-Eddy,Jeffrey L. Boore,Marcus C. Chibucos,Mary Coates,Paramvir S. Dehal,Kim D. Delehaunty,Suomeng Dong,Suomeng Dong,Polly Downton,Bernard Dumas,Bernard Dumas,Georgina Fabro,Catrina Fronick,Susan I. Fuerstenberg,Lucinda Fulton,Elodie Gaulin,Elodie Gaulin,Francine Govers,Linda Karen Hughes,Sean Humphray,Rays H. Y. Jiang,Rays H. Y. Jiang,Howard S. Judelson,Sophien Kamoun,Kim Kyung,Harold J. G. Meijer,Patrick Minx,Paul Morris,Joanne O. Nelson,Vipa Phuntumart,Dinah Qutob,Anne P. Rehmany,Alejandra Rougon-Cardoso,Peter Ryden,Trudy Torto-Alalibo,David J. Studholme,Yuanchao Wang,Joe Win,Jonathan Wood,Sandra W. Clifton,Jane Rogers,Guido Van den Ackerveken,Jonathan D. G. Jones,John M. McDowell,Jim Beynon,Brett M. Tyler,Brett M. Tyler +57 more
TL;DR: The genome sequence of the oomycete Hyaloperonospora arabidopsidis is reported, an obligate biotroph and natural pathogen of Arabidopsis thaliana, which exhibits dramatic reductions in genes encoding RXLR effectors, proteins associated with zoospore formation and motility, and enzymes for assimilation of inorganic nitrogen and sulfur.
Journal ArticleDOI
Molecular Cloning of ATR5Emoy2 from Hyaloperonospora arabidopsidis, an Avirulence Determinant That Triggers RPP5-Mediated Defense in Arabidopsis
Kate Bailey,Volkan Cevik,Nicholas Holton,Jane Byrne-Richardson,Kee Hoon Sohn,Mary Coates,Alison Woods-Tör,H Murat Aksoy,Linda Karen Hughes,Laura Baxter,Jonathan D. G. Jones,Jim Beynon,Eric B. Holub,Mahmut Tör +13 more
TL;DR: The cloning and molecular characterization of the gene encoding ATR5(Emoy2) is described, an avirulence protein from the downy mildew pathogen Hyaloperonospora arabidopsidis isolate Emoy2, which triggers defense response in host lines expressing the functional RPP5 allele from Landsberg erecta (Ler-0).
Data quality checking in highly replicated 2-dye microarray data sets
TL;DR: Working with a data set obtained from 176 2-dye customised CATMAv3 arrays, to study patterns of gene expression in the leaves of Arabidopsis thaliana during natural senescence, a suite of data quality checking functions within the R microarray analysis package MAANOVA are developed.