L
Lothar Rink
Researcher at RWTH Aachen University
Publications - 254
Citations - 15719
Lothar Rink is an academic researcher from RWTH Aachen University. The author has contributed to research in topics: Zinc & Immune system. The author has an hindex of 63, co-authored 235 publications receiving 13189 citations. Previous affiliations of Lothar Rink include University of Lübeck & Laval University.
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Journal ArticleDOI
Inter-individual differences in cytokine release in patients undergoing cardiac surgery with cardiopulmonary bypass
A Roth-Isigkeit,L Hasselbach,E. Ocklitz,S. Brückner,A. Ros,Hartmut Gehring,Peter Schmucker,Lothar Rink,M Seyfarth +8 more
TL;DR: In vitro and in vivo cytokine responses and white blood cell counts of patients with high versus low cytokine secretion after a coronary artery bypass grafting (CABG) procedure suggest close relationships between cytokine release in the postoperative period and inter‐individually varying patterns of cytokines release in patients undergoing CABG surgery with CPB.
Journal ArticleDOI
Zinc homeostasis and immunosenescence.
Martina Maywald,Lothar Rink +1 more
TL;DR: An impaired function of innate immune cells indicate a predominance of zinc deficiency in the elderly that may contribute to immunosenescence, and current findings about zinc deficiency and supplementation in elderly individuals are summarized.
Journal ArticleDOI
Stimulation of Human Peripheral Blood Mononuclear Cells by Zinc and Related Cations
TL;DR: It is shown that zinc addition in a serum- and lipopolysaccharide-free cell culture system leads to significantly enhanced levels of interleukin 1 beta and tumour necrosis factor alpha and to expression of the corresponding mRNA in human peripheral blood mononuclear cells (PBMC).
Journal ArticleDOI
Zinc deficiency and IL-6 −174G/C polymorphism in old people from different European countries: Effect of zinc supplementation. ZINCAGE study
Eugenio Mocchegiani,Robertina Giacconi,Laura Costarelli,Elisa Muti,Catia Cipriano,Silvia Tesei,Sara Pierpaoli,Cinzia Giuli,Roberta Papa,Fiorella Marcellini,Nazzarena Gasparini,Romeo Pierandrei,Francesco Piacenza,Ermina Mariani,Daniela Monti,George Dedoussis,Stavroula Kanoni,Georges Herbein,Tamas Fulop,Lothar Rink,Jolanta Jajte,Marco Malavolta +21 more
TL;DR: The sole assessment of plasma Zn level is not reliable to exclude C- carriers from Zn supplementation, and a possible explanation for the conflicting data on the identification of IL-6-174G as a "risk allele" based on different dietary intake in the studied population is suggested.