L
Lothar Rink
Researcher at RWTH Aachen University
Publications - 254
Citations - 15719
Lothar Rink is an academic researcher from RWTH Aachen University. The author has contributed to research in topics: Zinc & Immune system. The author has an hindex of 63, co-authored 235 publications receiving 13189 citations. Previous affiliations of Lothar Rink include University of Lübeck & Laval University.
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Vitamin D3 and zinc synergistically induce regulatory T cells and suppress interferon-γ production in mixed lymphocyte culture.
TL;DR: In this article , the combined action of zinc and vitamin D3 in different in vitro models for immune reactions was investigated, and it was shown that zinc augments the effect of vitamin D-3 in certain therapeutic and sub-therapeutic concentrations.
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Interferon-γ (IFN-γ) levels finally become stable with increasing age as revealed by using an ELISA corresponding to the bioactivity
TL;DR: It is demonstrated that IFN-γ is a more sensitive parameter for the actual status of the immune system, since its titer shows alterations faster than leukocyte subtyping.
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The Intracellular Free Zinc Level Is Vital for Treg Function and a Feasible Tool to Discriminate between Treg and Activated Th Cells.
TL;DR: It is hypothesized that the intracellular free zinc level in Th cells is essential in guaranteeing proper cellular function and can be used to discriminate Tregs from other Th cell subsets.
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Intracellular zinc during cell activation and zinc deficiency.
TL;DR: In this paper, the impact of cellular priming due to stimulation with interleukin (IL)-1, IL-2, IL 4, IL 6 or the chemokine CXCL12a and its subsequent influence on the intracellular free zinc concentration was examined.
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Effects of a short-term reduction in brain serotonin synthesis on the availability of the soluble leptin receptor in healthy women.
Florian D. Zepf,V. L. S. Dingerkus,K. Helmbold,Sarah Bubenzer-Busch,C.S. Biskup,Beate Herpertz-Dahlmann,Michael Schaab,Jürgen Kratzsch,Albrecht Eisert,Lothar Rink,Ulrich Hagenah,T. J. Gaber +11 more
TL;DR: Modelling of the effects of reduced brain 5-HT synthesis due to acute tryptophan depletion on levels of soluble leptin receptor (sOb-R), the main high-affinity leptin binding protein, in healthy adults using an exploratory approach found women, but not men, showed reduced s Ob-R concentrations after ATD administration.