Marco A. Marra

TL;DR: An improved reference sequence of the single-copy and middle-repetitive regions of the genome is reported, produced using cytogenetic mapping to mitotic and polytene chromosomes, clone-based finishing and BAC fingerprint verification, ordering of scaffolds by alignment to cDNA sequences, incorporation of other map and sequence data, and validation by whole-genome optical restriction mapping.

TL;DR: It is shown that skin-derived precursors (SKPs) derive from Sox2(+) hair follicle dermal cells and that these two cell populations are similar with regard to their transcriptome and functional properties.

TL;DR: Overall, Tag-seq is sensitive to rare transcripts, has less sequence composition bias relative to LongSAGE, and allows differential expression analysis for a greater range of transcripts, including transcripts encoding important regulatory molecules.

TL;DR: A physical map of the mouse genome that contains 296 contigs of overlapping bacterial clones and 16,992 unique markers is constructed, enabling identification of a mouse clone that corresponds to almost any position in the human genome.

TL;DR: Functional studies showed NOTCH3 signaling to be critical for this differentiation event to occur in vitro and provide an initial foundation for future delineation of mechanisms that perturb primitive human mammary cell growth and differentiation.