M
Marco A. Marra
Researcher at University of British Columbia
Publications - 657
Citations - 215376
Marco A. Marra is an academic researcher from University of British Columbia. The author has contributed to research in topics: Gene & Genome. The author has an hindex of 153, co-authored 620 publications receiving 184684 citations. Previous affiliations of Marco A. Marra include BC Cancer Agency & University of Washington.
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Journal ArticleDOI
Hive plots—rational approach to visualizing networks
TL;DR: Hive plots are introduced for generating informative, quantitative and comparable network layouts that depict network structure transparently, are simple to understand and can be easily tuned to identify patterns of interest.
Journal ArticleDOI
The Integrated Genomic Landscape of Thymic Epithelial Tumors
Milan Radovich,Curtis R. Pickering,Ina Felau,Gavin Ha,Hailei Zhang,Heejoon Jo,Katherine A. Hoadley,Pavana Anur,Jiexin Zhang,Michael D. McLellan,Reanne Bowlby,Thomas Matthew,Ludmila Danilova,Apurva M. Hegde,Jaegil Kim,Mark D.M. Leiserson,Geetika Sethi,Charles Lu,Michael Ryan,Xiaoping Su,Andrew D. Cherniack,Gordon Robertson,Rehan Akbani,Paul T. Spellman,John N. Weinstein,D. Neil Hayes,Ben Raphael,Tara M. Lichtenberg,Kristen M. Leraas,Jean C. Zenklusen,Adrian Ally,Elizabeth L. Appelbaum,J. Todd Auman,Miruna Balasundaram,Saianand Balu,Madhusmita Behera,Rameen Beroukhim,Mario Berrios,Giovanni Blandino,Tom Bodenheimer,Moiz S. Bootwalla,Jay Bowen,Denise Brooks,Flavio Mavignier Carcano,Rebecca Carlsen,André Lopes Carvalho,Patricia Castro,Lara Chalabreysse,Lynda Chin,Juok Cho,Gina Choe,Eric Chuah,Sudha Chudamani,Carrie Cibulskis,Leslie Cope,Matthew G. Cordes,Daniel Crain,Erin Curley,Timothy Defreitas,John A. Demchok,Frank C. Detterbeck,Noreen Dhalla,Hendrik Dienemann,W. Jeff Edenfield,Francesco Facciolo,Martin L. Ferguson,Scott Frazer,Catrina Fronick,Lucinda Fulton,Robert S. Fulton,Stacey Gabriel,Johanna Gardner,Julie M. Gastier-Foster,Nils Gehlenborg,Mark Gerken,Gad Getz,David I. Heiman,Shital Hobensack,Andrea Holbrook,Robert A. Holt,Alan P. Hoyle,Carolyn M. Hutter,Michael Ittmann,Stuart R. Jefferys,Corbin D. Jones,Steven J.M. Jones,Katayoon Kasaian,Patrick K. Kimes,Phillip H. Lai,Peter W. Laird,Michael S. Lawrence,Pei Lin,Jia Liu,Laxmi Lolla,Yiling Lu,Yussanne Ma,Dennis T. Maglinte,David Mallery,Elaine R. Mardis,Marco A. Marra,Julie S. Martin,Michael Mayo,Sam Meier,Michael Meister,Shaowu Meng,Matthew Meyerson,Piotr A. Mieczkowski,Christopher A. Miller,Gordon B. Mills,Richard A. Moore,Scott Morris,Lisle E. Mose,Thomas Muley,Andrew J. Mungall,Karen Mungall,Rashi Naresh,Yulia Newton,Michael S. Noble,Taofeek K. Owonikoko,Joel S. Parker,Joseph Paulaskis,Robert Penny,Charles M. Perou,Corinne Perrin,Todd Pihl,Amie Radenbaugh,Suresh S. Ramalingam,Nilsa C. Ramirez,Ralf J. Rieker,Jeffrey Roach,Sara Sadeghi,Gordon Saksena,Jacqueline E. Schein,Heather Schmidt,Steven E. Schumacher,Candace Shelton,Troy Shelton,Yan Shi,Juliann Shih,Gabriel Sica,Henrique César Santejo Silveira,Janae V. Simons,Payal Sipahimalani,Tara Skelly,Heidi J. Sofia,Matthew G. Soloway,Joshua M. Stuart,Qiang Sun,Angela Tam,Donghui Tan,Roy Tarnuzzer,Nina Thiessen,David Van Den Berg,Mohammad A. Vasef,Umadevi Veluvolu,Doug Voet,Vonn Walter,Yunhu Wan,Zhining Wang,Arne Warth,Cleo-Aron Weis,Daniel J. Weisenberger,Matthew D. Wilkerson,Lisa Wise,Tina Wong,Hsin-Ta Wu,Ye Wu,Liming Yang,Jiashan Zhang,Erik Zmuda,Junya Fujimoto,Cristovam Scapulatempo-Neto,Andre L. Moreira,David M. Hwang,James Huang,Mirella Marino,Robert Korst,Giuseppe Giaccone,Yesim Gökmen-Polar,Sunil Badve,Arun Rajan,Philipp Ströbel,Nicolas Girard,Ming-Sound Tsao,Alexander Marx,Anne S. Tsao,Patrick J. Loehrer +186 more
TL;DR: A molecular link between thymoma and the autoimmune disease myasthenia gravis is identified, characterized by tumoral overexpression of muscle autoantigens, and increased aneuploidy.
Journal ArticleDOI
A SAGE approach to discovery of genes involved in autophagic cell death.
Sharon M. Gorski,Suganthi Chittaranjan,Erin Pleasance,J.D. Freeman,Carrie L. Anderson,Richard Varhol,Shaun M. Coughlin,Scott Zuyderduyn,Steven J.M. Jones,Marco A. Marra +9 more
TL;DR: These analyses strongly support both the emerging notion that there is overlap with respect to the molecules involved in autophagic cell death and apoptosis, and that there are important differences.
Journal ArticleDOI
Double-Hit Gene Expression Signature Defines a Distinct Subgroup of Germinal Center B-Cell-Like Diffuse Large B-Cell Lymphoma.
Daisuke Ennishi,Aixiang Jiang,Merrill Boyle,Brett Collinge,Bruno M. Grande,Susana Ben-Neriah,Christopher Rushton,Jeffrey Tang,Nicole Thomas,Graham W. Slack,Pedro Farinha,Katsuyoshi Takata,Tomoko Miyata-Takata,Jeffrey W. Craig,Anja Mottok,Barbara Meissner,Saeed Saberi,Ali Bashashati,Diego Villa,Kerry J. Savage,Laurie H. Sehn,Robert Kridel,Andrew J. Mungall,Marco A. Marra,Sohrab P. Shah,Christian Steidl,Joseph M. Connors,Randy D. Gascoyne,Ryan D. Morin,David Scott +29 more
TL;DR: A clinically and biologically distinct subgroup of tumors within GCB-DLBCL characterized by a gene expression signature of HGBL-DH/TH- BCL2 is defined by an assay applicable to routinely available biopsy samples, which enables exploration of its utility to guide patient management.
Journal ArticleDOI
A Children's Oncology Group and TARGET initiative exploring the genetic landscape of Wilms tumor.
Samantha Gadd,Vicki Huff,Amy L. Walz,Ariadne H. A. G. Ooms,Amy E. Armstrong,Daniela S. Gerhard,Malcolm A. Smith,Jaime M. Guidry Auvil,Daoud Meerzaman,Qing Rong Chen,Chih Hao Hsu,Chunhua Yan,Cu Nguyen,Ying Hu,Leandro C. Hermida,Tanja M. Davidsen,Patee Gesuwan,Yussanne Ma,Zusheng Zong,Andrew J. Mungall,Richard A. Moore,Marco A. Marra,Jeffrey S. Dome,Charles G. Mullighan,Jing Ma,David A. Wheeler,Oliver A. Hampton,Nicole Ross,Julie M. Gastier-Foster,Stefan T. Arold,Elizabeth J. Perlman +30 more
TL;DR: Integrated analyses support two major classes of genetic changes that preserve the progenitor state and/or interrupt normal development in Wilms tumors.