M
Marco Salvetti
Researcher at Sapienza University of Rome
Publications - 294
Citations - 13327
Marco Salvetti is an academic researcher from Sapienza University of Rome. The author has contributed to research in topics: Multiple sclerosis & Medicine. The author has an hindex of 44, co-authored 263 publications receiving 10931 citations. Previous affiliations of Marco Salvetti include Max Planck Society & Istituto Neurologico Mediterraneo.
Papers
More filters
Journal ArticleDOI
Twins: mirrors of the immune system.
TL;DR: Important results from twin studies are reviewed and their potential value in multifactorial, immune-mediated diseases is highlighted.
Journal ArticleDOI
Predominant and stable T cell responses to regions of myelin basic protein can be detected in individual patients with multiple sclerosis.
Marco Salvetti,Giovanni Ristori,Mauro D'Amato,Carla Buttinelli,M. Falcone,Cesare Fieschi,Hartmut Wekerle,Carlo Pozzilli +7 more
TL;DR: To which extent the T cell response to MBP is heterogeneous in single subjects in terms of preferentially recognized regions of the molecule, major histocompatibility complex (MHC) restriction, and stability over time is investigated.
Journal ArticleDOI
DMTs and Covid-19 severity in MS: a pooled analysis from Italy and France.
Maria Pia Sormani,Marco Salvetti,Pierre Labauge,Irene Schiavetti,Hélène Zéphir,Luca Carmisciano,C. Bensa,Nicola Rossi,Jean Pelletier,Cinzia Cordioli,Sandra Vukusic,Lucia Moiola,Philippe Kerschen,Marta Radaelli,Marie Théaudin,Paolo Immovilli,Olivier Casez,Marco Capobianco,Jonathan Ciron,Maria Trojano,Bruno Stankoff,Alain Créange,Gioacchino Tedeschi,Pierre Clavelou,Giancarlo Comi,Eric Thouvenot,Mario Alberto Battaglia,Mario Alberto Battaglia,Thibault Moreau,Francesco Patti,Jérôme De Seze,Céline Louapre +31 more
TL;DR: In this article, the effect of DMTs on Covid-19 severity in patients with MS, with a pooled-analysis of two large cohorts from Italy and France, was assessed by multivariate ordinal-logistic models and pooled by a fixed-effect meta-analysis.
Journal ArticleDOI
The immune response to Mycobacterial 70-kDa heat shock proteins frequently involves autoreactive T cells and is quantitatively disregulated in multiple sclerosis
Marco Salvetti,Giovanni Ristori,Carla Buttinelli,P. Fiori,M. Falcone,Warwick J. Britton,Elizabeth Adams,Gregorino Paone,Maria Grazia Grasso,Carlo Pozzilli +9 more
TL;DR: Mapping experiments showing that the response to conserved epitopes of HSP70 is a frequent event in each of the three conditions studied, often leading to the cross-recognition of microbial and human sequences implicate the 70-kDa heat shock proteins in multiple sclerosis.
Journal ArticleDOI
Immunometabolic profiling of T cells from patients with relapsing-remitting multiple sclerosis reveals an impairment in glycolysis and mitochondrial respiration
Claudia La Rocca,Fortunata Carbone,Veronica De Rosa,Alessandra Colamatteo,Mario Galgani,Francesco Perna,Roberta Lanzillo,Vincenzo Brescia Morra,Giuseppe Orefice,Ilaria Cerillo,Ciro Florio,Giorgia Teresa Maniscalco,Marco Salvetti,Diego Centonze,Antonio Uccelli,Salvatore Longobardi,Andrea Visconti,Giuseppe Matarese +17 more
TL;DR: It is suggested that T cells from RRMS patients display a reduced engagement of glycolysis and mitochondrial respiration, reversible upon IFN beta-1a treatment, thus suggesting an involvement of an altered metabolism in the pathogenesis of MS.