Marco Salvetti

TL;DR: The link between glycolysis and Foxp3-E2 variants via enolase-1 shows a previously unknown mechanism for controlling the induction and function of Treg cells in health and in autoimmunity.

TL;DR: Findings indicate that substantial numbers of B cells that are infected with Epstein-Barr virus accumulate in these intrameningeal follicles and in white matter lesions and are probably the target of a cytotoxic immune response in MS.

TL;DR: MRI lesion load, OCB and age at CIS are validated as the strongest independent predictors of conversion to CDMS in this multicentre setting.

TL;DR: Variations of CD161 expression on CD8(+) T cells identify a subset of lymphocytes with proinflammatory characteristics that have not been previously reported in multiple sclerosis and are likely to contribute to disease immunopathology.

TL;DR: It is proposed that a favourably modified balance of regulatory and pro-inflammatory lymphocytes underlies the suppression of central nervous system inflammation in patients with multiple sclerosis following non-myeloablative autologous haematopoietic stem cell transplantation with a conditioning regimen consisting of cyclophosphamide and alemtuzumab.