M
Marina Nati
Researcher at Dresden University of Technology
Publications - 6
Citations - 579
Marina Nati is an academic researcher from Dresden University of Technology. The author has contributed to research in topics: Innate immune system & Inflammation. The author has an hindex of 5, co-authored 6 publications receiving 296 citations.
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Journal ArticleDOI
Innate Immune Training of Granulopoiesis Promotes Anti-tumor Activity.
Lydia Kalafati,Lydia Kalafati,Ioannis Kourtzelis,Ioannis Kourtzelis,Ioannis Kourtzelis,Jonas Schulte-Schrepping,Xiaofei Li,Aikaterini Hatzioannou,Tatyana Grinenko,Eman Hagag,Anupam Sinha,Anupam Sinha,Canan Has,Sevina Dietz,António Miguel de Jesus Domingues,Marina Nati,Sundary Sormendi,Ales Neuwirth,Antonios Chatzigeorgiou,Athanasios Ziogas,Mathias Lesche,Andreas Dahl,Ian Henry,Pallavi Subramanian,Ben Wielockx,Peter J. Murray,Peter Mirtschink,Kyoung-Jin Chung,Joachim L. Schultze,Joachim L. Schultze,Mihai G. Netea,Mihai G. Netea,George Hajishengallis,Panayotis Verginis,Panayotis Verginis,Ioannis Mitroulis,Ioannis Mitroulis,Triantafyllos Chavakis,Triantafyllos Chavakis +38 more
TL;DR: The findings identify a novel and therapeutically relevant anti-tumor facet of trained immunity involving appropriate rewiring of granulopoiesis, which is transmissible by bone marrow transplantation to recipient naive mice.
Journal ArticleDOI
A self-sustained loop of inflammation-driven inhibition of beige adipogenesis in obesity
Kyoung-Jin Chung,Antonios Chatzigeorgiou,Matina Economopoulou,Ruben Garcia-Martin,Vasileia Ismini Alexaki,Ioannis Mitroulis,Marina Nati,Janine Gebler,Tjalf Ziemssen,Susan Goelz,Julia Phieler,Jong-Hyung Lim,Katia Karalis,Thalia Papayannopoulou,Matthias Blüher,George Hajishengallis,Triantafyllos Chavakis +16 more
TL;DR: An inflammation-driven inhibitory mechanism of beige adipogenesis in obesity that required direct adhesive interactions between macrophages and adipocytes mediated by the integrin α4 and its counter-receptor VCAM-1 was delineated.
Journal ArticleDOI
The role of immune cells in metabolism-related liver inflammation and development of non-alcoholic steatohepatitis (NASH).
Marina Nati,David Haddad,Andreas L. Birkenfeld,Christian A. Koch,Triantafyllos Chavakis,Antonios Chatzigeorgiou +5 more
TL;DR: Recent advances regarding understanding the role of the various cells of the innate and adaptive immunity in NASH development and progression are summarized, and possible future therapeutic options and tools to interfere with disease progression are discussed.
Journal ArticleDOI
Loss of hepatic Mboat7 leads to liver fibrosis
Veera Raghavan Thangapandi,Oskar Knittelfelder,Mario Brosch,Eleonora Patsenker,Olga Vvedenskaya,Stephan Buch,Sebastian Hinz,Alexander Hendricks,Marina Nati,A Herrmann,Devavrat Ravindra Rekhade,Thomas Berg,Madlen Matz-Soja,Klaus Huse,Edda Klipp,Josch K. Pauling,Judith A. H. Wodke,Jacobo Miranda Ackerman,Malte von Bonin,Elmar Aigner,Christian Datz,Witigo von Schönfels,S Nehring,Sebastian Zeissig,Christoph Röcken,Andreas Dahl,Triantafyllos Chavakis,Felix Stickel,Andrej Shevchenko,Clemens Schafmayer,Jochen Hampe,Pallavi Subramanian +31 more
TL;DR: Mboat7 deficiency in mice and human points to an inflammation-independent pathway of liver fibrosis that may be mediated by lipid signalling and a potentially targetable treatment option in NAFLD.
Journal ArticleDOI
Innate immune cells in the adipose tissue
TL;DR: The immune cell-adipocyte crosstalk in the AT is an important regulator of AT function and systemic metabolism and is discussed with a special focus on the role of innate immune cells in AT inflammation and metabolic homeostasis in obesity.