A
A Herrmann
Researcher at Dresden University of Technology
Publications - 24
Citations - 1624
A Herrmann is an academic researcher from Dresden University of Technology. The author has contributed to research in topics: Fatty liver & International HapMap Project. The author has an hindex of 12, co-authored 22 publications receiving 1264 citations. Previous affiliations of A Herrmann include University of Kiel.
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Journal ArticleDOI
A genome-wide association study confirms PNPLA3 and identifies TM6SF2 and MBOAT7 as risk loci for alcohol-related cirrhosis
Stephan Buch,Felix Stickel,Eric Trepo,Michael J. Way,A Herrmann,Hans Dieter Nischalke,Mario Brosch,Jonas Rosendahl,Thomas Berg,Monika Ridinger,Marcella Rietschel,Andrew McQuillin,Josef Frank,Falk Kiefer,Stefan Schreiber,Wolfgang Lieb,Michael Soyka,Nasser Semmo,Elmar Aigner,Christian Datz,Renate Schmelz,Stefan Brückner,Sebastian Zeissig,Anna-Magdalena Stephan,Norbert Wodarz,Jacques Devière,Nicolas Clumeck,Christoph Sarrazin,Frank Lammert,Thierry Gustot,Pierre Deltenre,Pierre Deltenre,Henry Völzke,Markus M. Lerch,Julia Mayerle,Florian Eyer,Clemens Schafmayer,Sven Cichon,Markus M. Nöthen,Michael Nothnagel,David Ellinghaus,Klaus Huse,Andre Franke,Steffen Zopf,Claus Hellerbrand,Christophe Moreno,Denis Franchimont,Marsha Y. Morgan,Jochen Hampe +48 more
TL;DR: A genome-wide association study for alcohol-related cirrhosis in individuals of European descent with subsequent validation in two independent European cohorts is performed, suggesting that lipid turnover is important in the pathogenesis of alcohol- related Cirrhosis.
Journal ArticleDOI
DNA Methylation Analysis in Nonalcoholic Fatty Liver Disease Suggests Distinct Disease-Specific and Remodeling Signatures after Bariatric Surgery
M Ahrens,Ole Ammerpohl,Witigo von Schönfels,Julia Kolarova,Susanne Bens,Timo Itzel,Andreas Teufel,A Herrmann,Mario Brosch,Holger Hinrichsen,Wiebke Erhart,Jan Hendrik Egberts,Bence Sipos,Stefan Schreiber,Robert Häsler,Felix Stickel,Thomas Becker,Michael Krawczak,Christoph Röcken,Reiner Siebert,Clemens Schafmayer,Jochen Hampe +21 more
TL;DR: Liver samples from morbidly obese patients with all stages of NAFLD and controls were analyzed by array-based DNA methylation and mRNA expression profiling, providing an example of treatment-induced epigenetic organ remodeling in humans.
Journal ArticleDOI
Genome-wide search for novel human uORFs and N-terminal protein extensions using ribosomal footprinting
Claudia Fritsch,A Herrmann,Michael Nothnagel,Karol Szafranski,Klaus Huse,Frank Schumann,Stefan Schreiber,Matthias Platzer,Michael Krawczak,Jochen Hampe,Mario Brosch +10 more
TL;DR: A transcriptome-wide map of novel candidate TISs derived as part of the study will shed further light on the way in which human proteome diversity is influenced by alternative translation initiation and regulation.
Journal ArticleDOI
Comparison of Gene Expression Patterns Between Mouse Models of Nonalcoholic Fatty Liver Disease and Liver Tissues From Patients.
Andreas Teufel,Timo Itzel,Wiebke Erhart,Mario Brosch,X.-Y. Wang,Yong Ook Kim,Witigo von Schönfels,A Herrmann,Stefan Brückner,Felix Stickel,Jean-François Dufour,Triantafyllos Chavakis,Claus Hellerbrand,Rainer Spang,Thorsten Maass,Thomas Becker,Stefan Schreiber,Clemens Schafmayer,Detlef Schuppan,Jochen Hampe +19 more
TL;DR: On a pathway level, gene expression patterns in livers of mice on the high-fat diet were associated more closely with human fatty liver disease than other models.
Journal ArticleDOI
ASTD: The Alternative Splicing and Transcript Diversity database
Gautier Koscielny,Vincent Le Texier,Chellappa Gopalakrishnan,Vasudev Kumanduri,Jean-Jack M Riethoven,Francesco Nardone,Eleanor J Stanley,Christine Fallsehr,Oliver Hofmann,Meelis Kull,Meelis Kull,Eoghan D. Harrington,Stéphanie Boué,Eduardo Eyras,Mireya Plass,Fabrice Lopez,William Ritchie,Virginie Moucadel,Takeshi Ara,Heike Pospisil,A Herrmann,Jens Reich,Roderic Guigó,Peer Bork,Magnus von Knebel Doeberitz,Jaak Vilo,Jaak Vilo,Winston Hide,Rolf Apweiler,Thangavel Alphonse Thanaraj,Daniel Gautheret +30 more
TL;DR: Participating laboratories have experimentally validated a subset of ASTD-predicted alternative splice forms and alternative polyadenylation forms that were not previously reported.