M
Mark B. Feinberg
Researcher at International AIDS Vaccine Initiative
Publications - 133
Citations - 20223
Mark B. Feinberg is an academic researcher from International AIDS Vaccine Initiative. The author has contributed to research in topics: Virus & Viral replication. The author has an hindex of 60, co-authored 126 publications receiving 19881 citations. Previous affiliations of Mark B. Feinberg include Emory University & National Institutes of Health.
Papers
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Journal ArticleDOI
Guidelines for the use of antiretroviral agents in HIV-infected adults and adolescents
Anthony S. Fauci,John G. Bartlett,Eric P. Goosby,M. D. Smith,H. J. Kaiser,S. W. Chang,James M. Anderson,R. Armstead,A. C. Baker,David A Barr,Samuel A. Bozzette,S. Cox,M. Delaney,Fred M. Gordin,W. Greaves,M. Harrington,J. J. Henning,Martin S. Hirsch,J. Jacobs,Richard Marlink,C. Maxwell,J. W. Mellors,D. B. Nash,S. Perryman,Robert T. Schooley,R. Sherer,Stephen A. Spector,G. Torres,Paul A. Volberding,B. A. Brady,E. M. Daniels,D. Feigal,Mark B. Feinberg,H. D. Gayle,T. R. Graydon,Jonathan E. Kaplan,Abe M. Macher,R. F. Martin,Henry Masur,Lynne M. Mofenson,J. Murray,J. O'Neill,L. C. Perez,R. Riseberg,S. Shekar,Sharilyn K. Stanley,J. Whitescarver +46 more
TL;DR: These Guidelines were developed by the Panel* on Clinical Practices for Treatment of HIV Infection convened by the Department of Health and Human Services and the Henry J. Kaiser Family Foundation.
Journal ArticleDOI
Changes in thymic function with age and during the treatment of HIV infection
Daniel C. Douek,Richard D. McFarland,Phillip H. Keiser,Earl A. Gage,Janice M. Massey,Barton F. Haynes,Michael A. Polis,Ashley T. Haase,Mark B. Feinberg,John L. Sullivan,Beth D. Jamieson,Jerome A. Zack,Louis J. Picker,Richard A. Koup +13 more
TL;DR: It is found that, although thymic function declines with age, substantial output is maintained into late adulthood and this results indicate that the adult thymus can contribute to immune reconstitution following HAART.
Journal ArticleDOI
Endoproteolytic cleavage of gp160 is required for the activation of human immunodeficiency virus
Joseph M. McCune,Linda Rabin,Mark B. Feinberg,Miriam Lieberman,Jon C. Kosek,Gregory R. Reyes,Irving L. Weissman +6 more
TL;DR: In this study, the tryptic-like endoproteolytic cleavage site was removed by site-directed mutagenesis and replaced with a chymotryptic-like site and the resultant mutant, RIP7/mut10, was found to be indistinguishable from wild-type HIV when analyzed at the level of proviral replication, RNA processing, protein expression, and viral assembly.
Journal ArticleDOI
Nonpathogenic SIV infection of sooty mangabeys is characterized by limited bystander immunopathology despite chronic high-level viremia.
Guido Silvestri,Donald L. Sodora,Richard A. Koup,Richard A. Koup,Mirko Paiardini,Shawn P. O'Neil,Harold M. McClure,Silvija I. Staprans,Mark B. Feinberg +8 more
TL;DR: It is reported here that SIV-infected mangabeys maintain preserved T lymphocyte populations and regenerative capacity and manifest far lower levels of aberrant immune activation and apoptosis than are seen in pathogenic SIV and HIV infections.
Journal ArticleDOI
The trans-activator gene of HTLV-III is essential for virus replication
Amanda G. Fisher,Mark B. Feinberg,Steven F. Josephs,Mary E. Harper,L. M. Marselle,Gregory R. Reyes,Matthew A. Gonda,Anna Aldovini,Debouk C,Robert C. Gallo +9 more
TL;DR: It is shown that derivatives of a biologically competent molecular clone of HTLV-III, in which the tat-Ill gene is deleted or the normal splicing abrogated, failed to produce or expressed unusually low levels of virus, respectively, when transfected into T-cell cultures.