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Beth D. Jamieson
Researcher at University of California, Los Angeles
Publications - 102
Citations - 9476
Beth D. Jamieson is an academic researcher from University of California, Los Angeles. The author has contributed to research in topics: CD8 & T cell. The author has an hindex of 45, co-authored 98 publications receiving 8874 citations. Previous affiliations of Beth D. Jamieson include UCLA Medical Center.
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Journal ArticleDOI
Changes in thymic function with age and during the treatment of HIV infection
Daniel C. Douek,Richard D. McFarland,Phillip H. Keiser,Earl A. Gage,Janice M. Massey,Barton F. Haynes,Michael A. Polis,Ashley T. Haase,Mark B. Feinberg,John L. Sullivan,Beth D. Jamieson,Jerome A. Zack,Louis J. Picker,Richard A. Koup +13 more
TL;DR: It is found that, although thymic function declines with age, substantial output is maintained into late adulthood and this results indicate that the adult thymus can contribute to immune reconstitution following HAART.
Journal ArticleDOI
Cytotoxic T-cell memory without antigen
TL;DR: It is shown that memory CD8+ cytotoxic T lymphocytes persist indefinitely in the absence of priming antigen, retain the memory phenotype (CD44hi), and provide protection against virus challenge.
Journal ArticleDOI
LXR Signaling Couples Sterol Metabolism to Proliferation in the Acquired Immune Response
Steven J. Bensinger,Michelle N. Bradley,Sean B. Joseph,Noam Zelcer,Edith M. Janssen,Mary Ann Hausner,Roger Shih,John S. Parks,Peter A. Edwards,Beth D. Jamieson,Peter Tontonoz +10 more
TL;DR: It is demonstrated that cellular cholesterol levels in dividing T cells are maintained in part through reciprocal regulation of the LXR and SREBP transcriptional programs, and implicate LXR signaling in a metabolic checkpoint that modulates cell proliferation and immunity.
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An epigenetic clock analysis of race/ethnicity, sex, and coronary heart disease
Steve Horvath,Michael Gurven,Morgan E. Levine,Benjamin C. Trumble,Hillard Kaplan,Hooman Allayee,Beate Ritz,Brian H. Chen,Ake T. Lu,Tammy M. Rickabaugh,Beth D. Jamieson,Dianjianyi Sun,Shengxu Li,Wei Chen,Lluis Quintana-Murci,Maud Fagny,Michael S. Kobor,Philip S. Tsao,Philip S. Tsao,Alexander P. Reiner,Kerstin L. Edlefsen,Devin Absher,Themistocles L. Assimes +22 more
TL;DR: Epigenetic aging rates are significantly associated with sex, race/ethnicity, and to a lesser extent with CHD risk factors, but not with incident CHD outcomes.
Journal ArticleDOI
HIV-1 Infection Is Associated With an Earlier Occurrence of a Phenotype Related to Frailty
Loïc Desquilbet,Lisa P. Jacobson,Linda P. Fried,John P. Phair,Beth D. Jamieson,Marcy Holloway,Joseph B. Margolick +6 more
TL;DR: In this cohort, HIV infection was associated with an earlier occurrence of a phenotype that resembles the phenotype of frailty in older adults without HIV infection, and studies of frailt in the setting of HIV infection may help to clarify the biological mechanism ofFrailty.