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Mary E. Sabatini

Researcher at Harvard University

Publications -  22
Citations -  2771

Mary E. Sabatini is an academic researcher from Harvard University. The author has contributed to research in topics: Fertility preservation & Pregnancy rate. The author has an hindex of 12, co-authored 22 publications receiving 2420 citations. Previous affiliations of Mary E. Sabatini include University of Pittsburgh.

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A brain-specific microRNA regulates dendritic spine development

TL;DR: It is shown that a brain-specific microRNA, miR-134>, is localized to the synapto-dendritic compartment of rat hippocampal neurons and negatively regulates the size of dendritic spines—postsynaptic sites of excitatory synaptic transmission.
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AMH/MIS as a contraceptive that protects the ovarian reserve during chemotherapy

TL;DR: It is shown that long-term parenteral administration of superphysiological doses of MIS, using either an adeno-associated virus serotype 9 (AAV9) gene therapy vector or recombinant protein, resulted in a complete arrest of folliculogenesis in mice, representing a unique mechanism of contraception that spares the pool of quiescent primordial follicles (ovarian reserve).
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Specificity and timing of neocortical transcriptome changes in response to BDNF gene ablation during embryogenesis or adulthood.

TL;DR: Brain-derived neurotrophic factor appeared to be required to maintain gene expression in the SST-NPY-TAC1 subclass of GABA neurons, although the absence of BDNF did not alter their general phenotype as inhibitory neurons.
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Ovarian stimulation and in-vitro fertilization outcomes of cancer patients undergoing fertility preservation compared to age matched controls: a 17-year experience

TL;DR: Most IVF outcomes appear comparable for cancer patients and age-matched controls, but cancer patients had a higher likelihood of live birth resulting in twins and higher twin pregnancy rates may reflect lack of underlying infertility or need for cancer-specific transfer guidelines.