M
Mary E. Sabatini
Researcher at Harvard University
Publications - 22
Citations - 2771
Mary E. Sabatini is an academic researcher from Harvard University. The author has contributed to research in topics: Fertility preservation & Pregnancy rate. The author has an hindex of 12, co-authored 22 publications receiving 2420 citations. Previous affiliations of Mary E. Sabatini include University of Pittsburgh.
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Journal ArticleDOI
A brain-specific microRNA regulates dendritic spine development
Gerhard Schratt,Fabian Tuebing,Elizabeth A. Nigh,Elizabeth A. Nigh,Christina G. Kane,Christina G. Kane,Mary E. Sabatini,Michael A. Kiebler,Michael E. Greenberg,Michael E. Greenberg +9 more
TL;DR: It is shown that a brain-specific microRNA, miR-134>, is localized to the synapto-dendritic compartment of rat hippocampal neurons and negatively regulates the size of dendritic spines—postsynaptic sites of excitatory synaptic transmission.
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Cervicovaginal bacteria are a major modulator of host inflammatory responses in the female genital tract
Melis N. Anahtar,Melis N. Anahtar,Elizabeth H. Byrne,Kathleen E. Doherty,Brittany A. Bowman,Hidemi S. Yamamoto,Magali Soumillon,Nikita Padavattan,Nasreen Ismail,Amber Moodley,Mary E. Sabatini,Musie Ghebremichael,Chad Nusbaum,Curtis Huttenhower,Herbert W. Virgin,Thumbi Ndung'u,Thumbi Ndung'u,Krista L. Dong,Bruce D. Walker,Bruce D. Walker,Bruce D. Walker,Raina N. Fichorova,Douglas S. Kwon,Douglas S. Kwon +23 more
TL;DR: This study proposes a mechanism by which cervicovaginal microbiota impact genital inflammation and thereby might affect a woman's reproductive health, including her risk of acquiring HIV.
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AMH/MIS as a contraceptive that protects the ovarian reserve during chemotherapy
Motohiro Kano,Amanda Sosulski,Li Hua Zhang,Hatice D. Saatcioglu,Dan Wang,Nicholas Nagykery,Mary E. Sabatini,Guangping Gao,Patricia K. Donahoe,David Pépin +9 more
TL;DR: It is shown that long-term parenteral administration of superphysiological doses of MIS, using either an adeno-associated virus serotype 9 (AAV9) gene therapy vector or recombinant protein, resulted in a complete arrest of folliculogenesis in mice, representing a unique mechanism of contraception that spares the pool of quiescent primordial follicles (ovarian reserve).
Journal ArticleDOI
Specificity and timing of neocortical transcriptome changes in response to BDNF gene ablation during embryogenesis or adulthood.
C. Glorioso,Mary E. Sabatini,Travis Unger,Takanori Hashimoto,Lisa M. Monteggia,David A. Lewis,Karoly Mirnics +6 more
TL;DR: Brain-derived neurotrophic factor appeared to be required to maintain gene expression in the SST-NPY-TAC1 subclass of GABA neurons, although the absence of BDNF did not alter their general phenotype as inhibitory neurons.
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Ovarian stimulation and in-vitro fertilization outcomes of cancer patients undergoing fertility preservation compared to age matched controls: a 17-year experience
Eden R. Cardozo,Alexcis P. Thomson,Anatte E. Karmon,K.A. Dickinson,Diane L. Wright,Mary E. Sabatini +5 more
TL;DR: Most IVF outcomes appear comparable for cancer patients and age-matched controls, but cancer patients had a higher likelihood of live birth resulting in twins and higher twin pregnancy rates may reflect lack of underlying infertility or need for cancer-specific transfer guidelines.