M
Maximilian Reichert
Researcher at Technische Universität München
Publications - 87
Citations - 5820
Maximilian Reichert is an academic researcher from Technische Universität München. The author has contributed to research in topics: Pancreatic cancer & Cancer. The author has an hindex of 28, co-authored 65 publications receiving 4635 citations. Previous affiliations of Maximilian Reichert include Ludwig Maximilian University of Munich & University of Pennsylvania.
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Journal ArticleDOI
EMT and Dissemination Precede Pancreatic Tumor Formation
Andrew D. Rhim,Emily T. Mirek,Nicole M. Aiello,Anirban Maitra,Jennifer M. Bailey,Florencia McAllister,Maximilian Reichert,Gregory L. Beatty,Anil K. Rustgi,Robert H. Vonderheide,Steven D. Leach,Ben Z. Stanger +11 more
TL;DR: It is suggested that inflammation enhances cancer progression in part by facilitating EMT and entry into the circulation and tagged cells invaded and entered the bloodstream unexpectedly early, before frank malignancy could be detected by rigorous histologic analysis.
Journal ArticleDOI
Gremlin 1 identifies a skeletal stem cell with bone, cartilage, and reticular stromal potential.
Daniel L. Worthley,Michael Churchill,Jocelyn T. Compton,Yagnesh Tailor,Meenakshi Rao,Yiling Si,Daniel E. Levin,Matthew G. Schwartz,Aysu Uygur,Yoku Hayakawa,Stefanie Gross,Bernhard W. Renz,Wanda Setlik,Ashley N. Martinez,Xiaowei Chen,Saqib Nizami,Heon Goo Lee,H. Paco Kang,Jon Michael Caldwell,Samuel Asfaha,C. Benedikt Westphalen,C. Benedikt Westphalen,Trevor A. Graham,Guangchun Jin,Karan Nagar,Hongshan Wang,Mazen A. Kheirbek,Alka Kolhe,Jared Carpenter,Mark Glaire,Abhinav Nair,Simon Renders,Nicholas A. Manieri,Sureshkumar Muthupalani,James G. Fox,Maximilian Reichert,Andrew S. Giraud,Robert F. Schwabe,Jean Phillipe Pradere,Jean Phillipe Pradere,Katherine D. Walton,Ajay Prakash,Deborah L. Gumucio,Anil K. Rustgi,Thaddeus S. Stappenbeck,Richard A. Friedman,Michael D. Gershon,Peter A. Sims,Tracy C. Grikscheit,Francis Y. Lee,Gerard Karsenty,Siddhartha Mukherjee,Timothy C. Wang +52 more
TL;DR: Grem1 expression identifies distinct connective tissue stem cells in both the bone (OCR stem cells) and the intestine (iRSCs) that are cells of origin for the periepithelial intestinal mesenchymal sheath.
Gremlin 1 Identifies a Skeletal Stem Cell with Bone, Cartilage, and Reticular Stromal Potential
Daniel L. Worthley,Michael Churchill,Jocelyn T. Compton,Yagnesh Tailor,Meenakshi Rao,Yiling Si,Daniel E. Levin,Matthew G. Schwartz,Aysu Uygur,Yoku Hayakawa,Stefanie Gross,Bernhard W. Renz,Wanda Setlik,Ashley N. Martinez,Xiaowei Chen,Saqib Nizami,Heon Goo Lee,H. Paco Kang,Jon Michael Caldwell,Samuel Asfaha,C. Benedikt Westphalen,C. Benedikt Westphalen,Trevor A. Graham,Guangchun Jin,Karan Nagar,Hongshan Wang,Mazen A. Kheirbek,Alka Kolhe,Jared Carpenter,Mark Glaire,Abhinav Nair,Simon Renders,Nicholas A. Manieri,Sureshkumar Muthupalani,James G. Fox,Maximilian Reichert,Andrew S. Giraud,Robert F. Schwabe,Jean Phillipe Pradere,Jean Phillipe Pradere,Katherine D. Walton,Ajay Prakash,Deborah L. Gumucio,Anil K. Rustgi,Thaddeus S. Stappenbeck,Richard A. Friedman,Michael D. Gershon,Peter A. Sims,Tracy C. Grikscheit,Francis Y. Lee,Gerard Karsenty,Siddhartha Mukherjee,Timothy C. Wang +52 more
TL;DR: Grem1 expression identifies distinct connective tissue stem cells in both the bone (OCR stem cells) and the intestine (iRSCs) as discussed by the authors, which are cells of origin for the periepithelial intestinal mesenchymal sheath.
Journal ArticleDOI
Pdx1 maintains β-cell identity and function by repressing an α-cell program
Tao Gao,Brian D. McKenna,Changhong Li,Maximilian Reichert,James Nguyen,Tarjinder Singh,Chenghua Yang,Archana Pannikar,Nicolai M. Doliba,Tingting Zhang,Doris A. Stoffers,Helena Edlund,Franz M. Matschinsky,Roland Stein,Ben Z. Stanger +14 more
TL;DR: Findings indicate that Pdx1 acts as a master regulator of β cell fate by simultaneously activating genes essential for β cell identity and repressing those associated with α cell identity.
Journal ArticleDOI
β2 Adrenergic-Neurotrophin Feedforward Loop Promotes Pancreatic Cancer
Bernhard W. Renz,Bernhard W. Renz,Ryota Takahashi,Takayuki Tanaka,Marina Macchini,Yoku Hayakawa,Yoku Hayakawa,Zahra Dantes,H. Carlo Maurer,Xiaowei Chen,Zhengyu Jiang,C. Benedikt Westphalen,C. Benedikt Westphalen,Matthias Ilmer,Giovanni Valenti,Sarajo Mohanta,Andreas J. R. Habenicht,Moritz Middelhoff,Timothy Chu,Karan Nagar,Yagnesh Tailor,Riccardo Casadei,Mariacristina Di Marco,Axel Kleespies,Richard A. Friedman,Helen Remotti,Maximilian Reichert,Daniel L. Worthley,Daniel L. Worthley,Jens Neumann,Jens Werner,Alina Iuga,Kenneth P. Olive,Timothy C. Wang +33 more
TL;DR: Findings suggest that catecholamines drive a feedforward loop, whereby upregulation of neurotrophins increases sympathetic innervation and local norepinephrine accumulation in PDAC patients on nonselective β-blockers.