H
Hongshan Wang
Researcher at Fudan University
Publications - 20
Citations - 1367
Hongshan Wang is an academic researcher from Fudan University. The author has contributed to research in topics: Stem cell & Progenitor cell. The author has an hindex of 11, co-authored 20 publications receiving 1173 citations. Previous affiliations of Hongshan Wang include Columbia University Medical Center & Columbia University.
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Journal ArticleDOI
Gremlin 1 identifies a skeletal stem cell with bone, cartilage, and reticular stromal potential.
Daniel L. Worthley,Michael Churchill,Jocelyn T. Compton,Yagnesh Tailor,Meenakshi Rao,Yiling Si,Daniel E. Levin,Matthew G. Schwartz,Aysu Uygur,Yoku Hayakawa,Stefanie Gross,Bernhard W. Renz,Wanda Setlik,Ashley N. Martinez,Xiaowei Chen,Saqib Nizami,Heon Goo Lee,H. Paco Kang,Jon Michael Caldwell,Samuel Asfaha,C. Benedikt Westphalen,C. Benedikt Westphalen,Trevor A. Graham,Guangchun Jin,Karan Nagar,Hongshan Wang,Mazen A. Kheirbek,Alka Kolhe,Jared Carpenter,Mark Glaire,Abhinav Nair,Simon Renders,Nicholas A. Manieri,Sureshkumar Muthupalani,James G. Fox,Maximilian Reichert,Andrew S. Giraud,Robert F. Schwabe,Jean Phillipe Pradere,Jean Phillipe Pradere,Katherine D. Walton,Ajay Prakash,Deborah L. Gumucio,Anil K. Rustgi,Thaddeus S. Stappenbeck,Richard A. Friedman,Michael D. Gershon,Peter A. Sims,Tracy C. Grikscheit,Francis Y. Lee,Gerard Karsenty,Siddhartha Mukherjee,Timothy C. Wang +52 more
TL;DR: Grem1 expression identifies distinct connective tissue stem cells in both the bone (OCR stem cells) and the intestine (iRSCs) that are cells of origin for the periepithelial intestinal mesenchymal sheath.
Gremlin 1 Identifies a Skeletal Stem Cell with Bone, Cartilage, and Reticular Stromal Potential
Daniel L. Worthley,Michael Churchill,Jocelyn T. Compton,Yagnesh Tailor,Meenakshi Rao,Yiling Si,Daniel E. Levin,Matthew G. Schwartz,Aysu Uygur,Yoku Hayakawa,Stefanie Gross,Bernhard W. Renz,Wanda Setlik,Ashley N. Martinez,Xiaowei Chen,Saqib Nizami,Heon Goo Lee,H. Paco Kang,Jon Michael Caldwell,Samuel Asfaha,C. Benedikt Westphalen,C. Benedikt Westphalen,Trevor A. Graham,Guangchun Jin,Karan Nagar,Hongshan Wang,Mazen A. Kheirbek,Alka Kolhe,Jared Carpenter,Mark Glaire,Abhinav Nair,Simon Renders,Nicholas A. Manieri,Sureshkumar Muthupalani,James G. Fox,Maximilian Reichert,Andrew S. Giraud,Robert F. Schwabe,Jean Phillipe Pradere,Jean Phillipe Pradere,Katherine D. Walton,Ajay Prakash,Deborah L. Gumucio,Anil K. Rustgi,Thaddeus S. Stappenbeck,Richard A. Friedman,Michael D. Gershon,Peter A. Sims,Tracy C. Grikscheit,Francis Y. Lee,Gerard Karsenty,Siddhartha Mukherjee,Timothy C. Wang +52 more
TL;DR: Grem1 expression identifies distinct connective tissue stem cells in both the bone (OCR stem cells) and the intestine (iRSCs) as discussed by the authors, which are cells of origin for the periepithelial intestinal mesenchymal sheath.
Mist1 Expressing Gastric Stem Cells Maintain the Normal and Neoplastic Gastric Epithelium and Are Supported by a Perivascular Stem Cell Niche
Yoku Hayakawa,Hiroshi Ariyama,Jitka Stancikova,Kosuke Sakitani,Samuel Asfaha,Bernhard W. Renz,Zinaida A. Dubeykovskaya,Wataru Shibata,Hongshan Wang,Christoph B. Westphalen,Xiaowei Chen,Yoshihiro Takemoto,Woosook Kim,Shradha S. Khurana,Yagnesh Tailor,Karan Nagar,Hiroyuki Tomita,Akira Hara,Antonia R. Sepulveda,Wanda Setlik,Michael D. Gershon,Subhrajit Saha,Lei Ding,Richard A. Friedman,Stephen F. Konieczny,Daniel L. Worthley,Vladimir Korinek,Timothy C. Wang,Zeli Shen,James G. Fox +29 more
TL;DR: In this article, the authors proposed a new method for cancer drug discovery based on protein-protein interactions, and obtained grants from the National Institutes of Health (U.S.) (Grants 54CA126513, R01CA093405, R1CA120979, and R1DK052778).
Journal ArticleDOI
Bone Marrow Myeloid Cells Regulate Myeloid-Biased Hematopoietic Stem Cells via a Histamine-Dependent Feedback Loop.
Xiaowei Chen,Huan Deng,Michael Churchill,Larry L. Luchsinger,Xing Du,Timothy Chu,Richard A. Friedman,Moritz Middelhoff,Hongxu Ding,Hongxu Ding,Yagnesh Tailor,Alexander L.E. Wang,Haibo Liu,Zhengchuan Niu,Zhengchuan Niu,Hongshan Wang,Hongshan Wang,Zhenyu Jiang,Simon Renders,Simon Renders,Siu Hong Ho,Spandan V. Shah,Pavel Tishchenko,Wenju Chang,Wenju Chang,Theresa Swayne,Laura Munteanu,Andrea Califano,Andrea Califano,Ryota Takahashi,Karan Nagar,Bernhard W. Renz,Bernhard W. Renz,Daniel L. Worthley,C. Benedikt Westphalen,C. Benedikt Westphalen,Yoku Hayakawa,Yoku Hayakawa,Samuel Asfaha,Samuel Asfaha,Florence Borot,Chyuan Sheng Lin,Hans-Willem Snoeck,Siddhartha Mukherjee,Timothy C. Wang +44 more
TL;DR: An auto-/paracrine physiologic circuit that controls quiescence of MB-HSCs and hematopoietic progenitors marked by histidine decarboxylase is described, which couples lineage-specific physiological demands to intrinsically primed MB- HSCs to enforce homeostasis.
Journal ArticleDOI
Bone marrow mesenchymal stem cells promote the repair of islets from diabetic mice through paracrine actions.
TL;DR: Data suggest that the PI3K/Akt signal pathway plays a critical role in β cell proliferation after MSC transplantation, which can ameliorate hyperglycemia in diabetic mice by promoting the regeneration of β cells.