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Michael A. Province

Researcher at Washington University in St. Louis

Publications -  409
Citations -  40871

Michael A. Province is an academic researcher from Washington University in St. Louis. The author has contributed to research in topics: Genome-wide association study & Population. The author has an hindex of 79, co-authored 396 publications receiving 37334 citations. Previous affiliations of Michael A. Province include Jewish Hospital & Harvard University.

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The heritage family study : quality assurance and quality control

TL;DR: The quality assurance and quality control measures implemented in the HERITAGE Family Study are described, including some examples with real data.
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Distribution of Regional Density and Vascular Permeability in the Adult Respiratory Distress Syndrome

TL;DR: Analysis of data obtained by analyzing previously reported data confirmed that ventral-dorsal gradients in LD and EVD exist in patients with ARDS, and confirmed that no consistent Ventral-Dorsal distribution of increased pulmonary vascular permeability is present.
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CMDS: A population-based method for identifying recurrent DNA copy number aberrations in cancer from high-resolution data

TL;DR: CMDS provides a fast, powerful and easily implemented tool for the RCNA analysis of large-scale data from cancer genomes and is statistically powerful, computationally efficient and particularly suitable for high-resolution and large-population studies.
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Association between the α-adducin gene and hypertension in the HyperGEN Study

TL;DR: The α-adducin gene remained a significant independent predictor of hypertension in a multivariate logistic model even after correcting for other risk factors for hypertension, including gender, age, body mass index (BMI), smoking, LDL cholesterol, triglycerides, urine sodium (Na), and urine potassium (K), and through the use of regression trees, several gene-by-environment interactions were implicated.
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Association study of CRP gene polymorphisms with serum CRP level and cardiovascular risk in the NHLBI Family Heart Study

TL;DR: A strong impact of local SNPs of the CRP gene on plasma CRP levels is indicated, but there was no direct evidence that these genetically controlled CRP elevations by local CRP SNPs contributed to cardiovascular disease phenotypes.