M
Michael A. Province
Researcher at Washington University in St. Louis
Publications - 409
Citations - 40871
Michael A. Province is an academic researcher from Washington University in St. Louis. The author has contributed to research in topics: Genome-wide association study & Population. The author has an hindex of 79, co-authored 396 publications receiving 37334 citations. Previous affiliations of Michael A. Province include Jewish Hospital & Harvard University.
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Journal ArticleDOI
WDTC1, the ortholog of Drosophila adipose gene, associates with human obesity, modulated by MUFA intake.
Chao-Qiang Lai,Laurence D. Parnell,Donna K. Arnett,Bibiana Garcia-Bailo,Michael Y. Tsai,Edmond K. Kabagambe,Robert J. Straka,Michael A. Province,Ping An,Ingrid B. Borecki,Katherine L. Tucker,Jose M. Ordovas +11 more
TL;DR: It is suggested that WDTC1 variation may be an important risk factor contributing to obesity in these populations, given the high frequency of the major alleles in both populations.
Loss of Cardioprotective Effects at the ADAMTS7 Locus as a Result of Gene-Smoking Interactions
Danish Saleheen,Wei Zhao,Robin Young,Christopher P. Nelson,Weang Kee Ho,Jane F. Ferguson,Asif Rasheed,Kristy Ou,Sylvia T. Nurnberg,Robert C. Bauer,Anuj Goel,Ron Do,Alexandre F.R. Stewart,Jaana Hartiala,Weihua Zhang,Gudmar Thorleifsson,Rona J. Strawbridge,Juha Sinisalo,Stavroula Kanoni,Sanaz Sedaghat,Eirini Marouli,Kati Kristiansson,Jing Hua Zhao,Robert A. Scott,Dominique Gauguier,Svati H. Shah,Albert V. Smith,Natalie R. van Zuydam,Amanda J. Cox,Christina Willenborg,Thorsten Kessler,Lingyao Zeng,Michael A. Province,Andrea Ganna,Lars Lind,Nancy L. Pedersen,Charles C. White,Anni Joensuu,Marcus E. Kleber,Alistair S. Hall,Winfried Maerz,Veikko Salomaa,Christopher J. O'Donnell,Erik Ingelsson,Mary F. Feitosa,Jeanette Erdmann,Donald W. Bowden,Colin N. A. Palmer,Vilmundur Gudnason,Ulf de Faire,Pierre Zalloua,Nicholas J. Wareham,John R. Thompson,Kari Kuulasmaa,George Dedoussis,Markus Perola,Abbas Dehghan,John C. Chambers,Jaspal S. Kooner,Hooman Allayee,Panos Deloukas,Ruth McPherson,Kari Stefansson,Heribert Schunkert,Sekar Kathiresan,Martin Farrall,Philippe M. Frossard,Daniel J. Rader,Nilesh J. Samani,Muredach P. Reilly +69 more
Journal ArticleDOI
The SCARB1 gene is associated with lipid response to dietary and pharmacological interventions
Yongjun Liu,Jose M. Ordovas,Guimin Gao,Michael A. Province,Robert J. Straka,Michael Y. Tsai,Chao-Qiang Lai,Kui Zhang,Ingrid B. Borecki,James E. Hixson,David B. Allison,Donna K. Arnett +11 more
TL;DR: It is suggested that the SCARB1 gene may serve as a useful marker that predicts variation in baseline lipid levels, postprandial lipid response, and response to fenofibrate intervention.
Journal ArticleDOI
Identification of a novel 5–base pair deletion in calcineurin B (PPP3R1) promoter region and its association with left ventricular hypertrophy
Weihong Tang,Donna K. Arnett,Richard B. Devereux,Demetrios Panagiotou,Michael A. Province,Michael B. Miller,Giovanni de Simone,Charles Gu,Robert E. Ferrell +8 more
TL;DR: The 5-base pair deletion within the CnB gene may cause excessive LV growth beyond the level appropriate for cardiac workload when exposed to severe hypertension or may be in linkage disequilibrium with the causal mutation.
Journal ArticleDOI
Role of gene expression microarray analysis in finding complex disease genes.
TL;DR: This paper identifies several statistical problems related to the application of GEMA to genetic epidemiological analysis, and considers study designs that might benefit from this promising new technology.