M
Michael A. Province
Researcher at Washington University in St. Louis
Publications - 409
Citations - 40871
Michael A. Province is an academic researcher from Washington University in St. Louis. The author has contributed to research in topics: Genome-wide association study & Population. The author has an hindex of 79, co-authored 396 publications receiving 37334 citations. Previous affiliations of Michael A. Province include Jewish Hospital & Harvard University.
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Journal ArticleDOI
A genome-wide scan for urinary albumin excretion in hypertensive families.
Barry I. Freedman,Stephanie R Beck,Stephen S. Rich,Gerardo Heiss,Cora E. Lewis,Stephen T. Turner,Michael A. Province,Karen Schwander,Donna K. Arnett,Beverly G. Mellen +9 more
TL;DR: These analyses demonstrate the marked heritability of urine ACR in families enriched for the presence of members with essential hypertension and suggest that a gene(s) associated with urinary ACR may be present on human chromosomes 19 and 12.
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Evidence for multiple determinants of the body mass index: the National Heart, Lung, and Blood Institute Family Heart Study.
Ingrid B. Borecki,Millicent Higgins,Pamela J. Schreiner,Donna K. Arnett,Elizabeth J. Mayer-Davis,Steven C. Hunt,Michael A. Province +6 more
TL;DR: Genetic analysis revealed the presence of two maximum likelihood solutions, one characterized as a recessive Mendelian gene and the other as a major effect with an ambiguous transmission pattern, consistent with detection of two separate factors influencing the BMI distribution in a substantive manner.
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Modulation of Hemodynamic and Vascular Filtration Changes in Diabetic Rats by Dietary myo-inositol
Giuseppe Pugliese,Ronald G. Tilton,Amanda Speedy,Elettra Santarelli,Donald M Eades,Michael A. Province,Charles Kilo,William R. Sherman,Joseph R. Williamson +8 more
TL;DR: The observations indicate that diabetes-induced increases in regional blood flow, 131I-BSA permeation, GFR, and urinary protein excretion can be markedly reduced or normalized by consumption of myo-inositol-supplemented diets that raise plasmaMyo- inositol levels approximately fivefold.
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Variability of Pulmonary Function in Alpha-1-Antitrypsin Deficiency: Residual Family Resemblance beyond the Effect of the Pi Locus
TL;DR: This investigation demonstrates the feasibility of dissecting residual familial effects on complex multifactorial traits in alpha 1-antitrypsin-deficient individuals and their families and indicates a drop in the importance of genetic factors.
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Dietary Linolenic Acid Is Associated With a Lower Prevalence of Hypertension in the NHLBI Family Heart Study
Luc Djoussé,Donna K. Arnett,James S. Pankow,Paul N. Hopkins,Michael A. Province,R. Curtis Ellison +5 more
TL;DR: Dietary linolenic acid is associated with a lower prevalence of hypertension and lower systolic blood pressure in white subjects, andLinoleic acid, an omega-6 fatty acid, was not associated with prevalent hypertension or blood pressure.