M
Michael A. Province
Researcher at Washington University in St. Louis
Publications - 409
Citations - 40871
Michael A. Province is an academic researcher from Washington University in St. Louis. The author has contributed to research in topics: Genome-wide association study & Population. The author has an hindex of 79, co-authored 396 publications receiving 37334 citations. Previous affiliations of Michael A. Province include Jewish Hospital & Harvard University.
Papers
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Journal ArticleDOI
Effects of Similarities in Lifestyle Habits on Familial Aggregation of High Density Lipoprotein and Low Density Lipoprotein Cholesterol: The NHLBI Family Heart Study
R C Ellison,Richard H. Myers,Yuqing Zhang,Luc Djoussé,Sarah S. Knox,Roger R. Williams,Michael A. Province +6 more
TL;DR: It is suggested that lifestyle factors have little effect on the familial aggregation of HDL and LDL cholesterol.
Journal ArticleDOI
Fibrinogen, Plasminogen Activator Inhibitor-1, and Carotid Intima-Media Wall Thickness in the NHLBI Family Heart Study
Aaron R. Folsom,James S. Pankow,Roger R. Williams,Gregory W. Evans,Michael A. Province,John H. Eckfeldt +5 more
TL;DR: The data suggest 1) elevated fibrinogen and PAI-1 do not explain clustering of CHD in families and 2) fibr inogen andPAi-1 may partly mediate the effects of other risk factors on carotid atherosclerosis, though the data are also consistent with them playing no causal role.
Book
Genetic dissection of complex traits
TL;DR: The present work presents a meta-analysis of Model-free methods for Linkage Analysis and classification Methods for Confronting Heterogeneity for Complex Inheritance, which aims to clarify the genetic architecture of a Multivariate Phenotype.
Journal ArticleDOI
A multi-ancestry genome-wide study incorporating gene–smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure
Yun Ju Sung,Lisa de las Fuentes,Thomas W. Winkler,Daniel I. Chasman,Amy R. Bentley,Aldi T. Kraja,Ioanna Ntalla,Helen R. Warren,Xiuqing Guo,Karen Schwander,Alisa K. Manning,Alisa K. Manning,Michael R. Brown,Hugues Aschard,Hugues Aschard,Mary F. Feitosa,Nora Franceschini,Yingchang Lu,Ching-Yu Cheng,Xueling Sim,Dina Vojinovic,Jonathan Marten,Solomon K. Musani,Tuomas O. Kilpeläinen,Tuomas O. Kilpeläinen,Melissa A. Richard,Stella Aslibekyan,Traci M. Bartz,Rajkumar Dorajoo,Changwei Li,Yongmei Liu,Tuomo Rankinen,Albert V. Smith,Salman M. Tajuddin,Bamidele O. Tayo,Wei Zhao,Yanhua Zhou,Nana Matoba,Tamar Sofer,Tamar Sofer,Maris Alver,Marzyeh Amini,Mathilde Boissel,Jin-Fang Chai,Xu Chen,Jasmin Divers,Ilaria Gandin,Chuan Gao,Franco Giulianini,Anuj Goel,Sarah E. Harris,Fernando Pires Hartwig,Fernando Pires Hartwig,Meian He,Andrea R. V. R. Horimoto,Fang-Chi Hsu,Anne U. Jackson,Candace M Kammerer,Anuradhani Kasturiratne,Pirjo Komulainen,B. Kuhnel,Karin Leander,Wen-Jane Lee,Keng-Hung Lin,Jian'an Luan,Leo-Pekka Lyytikäinen,Leo-Pekka Lyytikäinen,Colin A McKenzie,Christopher P. Nelson,Christopher P. Nelson,Raymond Noordam,Robert A. Scott,Wayne Huey-Herng Sheu,Alena Stančáková,Fumihiko Takeuchi,Peter J. van der Most,Tibor V. Varga,RJ Waken,Heming Wang,Heming Wang,Yajuan Wang,Erin B. Ware,Stefan Weiss,Wanqing Wen,Lisa R. Yanek,Weihua Zhang,Weihua Zhang,Jing Hua Zhao,Saima Afaq,Tamuno Alfred,Najaf Amin,Dan E. Arking,Tin Aung,R. Graham Barr,Lawrence F. Bielak,Eric Boerwinkle,Eric Boerwinkle,Erwin P. Bottinger,Peter S. Braund,Peter S. Braund,Jennifer A. Brody,Ulrich Broeckel,Brian E. Cade,Archie Campbell,Mickaël Canouil,Aravinda Chakravarti,Massimiliano Cocca,Francis S. Collins,John M. C. Connell,Renée de Mutsert,H. Janaka de Silva,Marcus Dörr,Qing Duan,Charles B. Eaton,Georg Ehret,Georg Ehret,Evangelos Evangelou,Evangelos Evangelou,Jessica D. Faul,Nita G. Forouhi,Oscar H. Franco,Yechiel Friedlander,He Gao,Bruna Gigante,C. Charles Gu,Preeti Gupta,Saskia P. Hagenaars,Tamara B. Harris,Jiang He,Sami Heikkinen,Chew-Kiat Heng,Chew-Kiat Heng,Albert Hofman,Barbara V. Howard,Barbara V. Howard,Steven C. Hunt,Steven C. Hunt,Marguerite R. Irvin,Yucheng Jia,Tomohiro Katsuya,Joel D. Kaufman,Nicola D. Kerrison,Chiea Chuen Khor,Chiea Chuen Khor,Woon-Puay Koh,Heikki A. Koistinen,Heikki A. Koistinen,Heikki A. Koistinen,Charles Kooperberg,Jose E Krieger,Michiaki Kubo,Zoltán Kutalik,Zoltán Kutalik,Johanna Kuusisto,Timo A. Lakka,Carl D. Langefeld,Claudia Langenberg,Lenore J. Launer,Joseph H. Lee,Benjamin Lehne,Daniel Levy,Cora E. Lewis,Yize Li,Sing Hui Lim,Ching-Ti Liu,Jianjun Liu,Jianjun Liu,Jingmin Liu,Y Liu,Marie Loh,Marie Loh,Kurt Lohman,Tin Louie,Reedik Mägi,Koichi Matsuda,Thomas Meitinger,Andres Metspalu,Lili Milani,Yukihide Momozawa,Thomas H. Mosley,Mike A. Nalls,Ubaydah Nasri,Jeffrey R. O'Connell,Adesola Ogunniyi,Walter Palmas,Nicholette D. Palmer,James S. Pankow,Nancy L. Pedersen,Annette Peters,Patricia A. Peyser,Ozren Polasek,David J. Porteous,Olli T. Raitakari,Olli T. Raitakari,Frida Renström,Frida Renström,Treva Rice,Paul M. Ridker,Antonietta Robino,Jennifer G. Robinson,Lynda M. Rose,Igor Rudan,Charumathi Sabanayagam,Babatunde L. Salako,Kevin Sandow,Carsten Oliver Schmidt,Pamela J. Schreiner,William R. Scott,William R. Scott,Peter S. Sever,Mario Sims,Colleen M. Sitlani,Blair H. Smith,Jennifer A. Smith,Harold Snieder,John M. Starr,Konstantin Strauch,Hua Tang,Kent D. Taylor,Yik Ying Teo,Yih Chung Tham,André G. Uitterlinden,M. Waldenberger,Lihua Wang,Ya Xing Wang,Wen Bin Wei,Gregory P. Wilson,Mary K. Wojczynski,Yong-Bing Xiang,Jie Yao,Jian-Min Yuan,Alan B. Zonderman,Diane M. Becker,Michael Boehnke,Donald W. Bowden,John C. Chambers,John C. Chambers,Yii-Der Ida Chen,David R. Weir,Ulf de Faire,Ian J. Deary,Tõnu Esko,Tõnu Esko,Martin Farrall,Terrence Forrester,Barry I. Freedman,Philippe Froguel,Philippe Froguel,Paolo Gasparini,Paolo Gasparini,Christian Gieger,Bernardo L. Horta,Yi-Jen Hung,Jost B. Jonas,Jost B. Jonas,Norihiro Kato,Jaspal S. Kooner,Jaspal S. Kooner,Markku Laakso,Terho Lehtimäki,Kae-Woei Liang,Kae-Woei Liang,Patrik K. E. Magnusson,Albertine J. Oldehinkel,Alexandre C. Pereira,Alexandre C. Pereira,Thomas T. Perls,Rainer Rauramaa,Susan Redline,Rainer Rettig,Nilesh J. Samani,Nilesh J. Samani,James Scott,Xiao-Ou Shu,Pim van der Harst,Lynne E. Wagenknecht,Nicholas J. Wareham,Hugh Watkins,Ananda R. Wickremasinghe,Tangchun Wu,Yoichiro Kamatani,Cathy C. Laurie,Claude Bouchard,Richard S. Cooper,Michele K. Evans,Vilmundur Gudnason,James E. Hixson,Sharon L.R. Kardia,Stephen B. Kritchevsky,Bruce M. Psaty,Bruce M. Psaty,Rob M. van Dam,Donna K. Arnett,Dennis O. Mook-Kanamori,Myriam Fornage,Ervin R. Fox,Caroline Hayward,Cornelia M. van Duijn,E. Shyong Tai,Tien Yin Wong,Ruth J. F. Loos,Alexander P. Reiner,Charles N. Rotimi,Laura J. Bierut,Xiaofeng Zhu,L. Adrienne Cupples,Michael A. Province,Jerome I. Rotter,Paul W. Franks,Paul W. Franks,Paul W. Franks,Kenneth Rice,Paul Elliott,Mark J. Caulfield,W. James Gauderman,Patricia B. Munroe,Dabeeru C. Rao,Alanna C. Morrison +317 more
TL;DR: A genome-wide gene-smoking interaction study of mean arterial pressure (MAP) and pulse pressure (PP) in 129 913 individuals in stage 1 and follow-up analysis in 480 178 additional individuals in stages 2 identified 136 loci significantly associated with MAP and/or PP and identified nine new signals near known loci.
Journal ArticleDOI
Meta-analysis of genome-wide scans for blood pressure in African American and Nigerian samples. The National Heart, Lung, and Blood Institute GeneLink Project.
Treva Rice,Richard S. Cooper,Xiaodong Wu,Claude Bouchard,Tuomo Rankinen,D. C. Rao,Cashell E. Jaquish,Richard R. Fabsitz,Michael A. Province +8 more
TL;DR: Follow-up studies involving positional cloning efforts of the combined families showing linkage evidence in these regions (particularly 2p and 7p) may be warranted to verify these findings and identify the genes and causative variants.