Mick Correll

TL;DR: It is shown that systematic analyses of host targets of viral proteins can identify cancer genes with a success rate on a par with their identification through functional genomics and large-scale cataloguing of tumour mutations, to increase the specificity of cancer gene identification.

TL;DR: Reduction of cyclin D1 levels in human cancer cells impaired recruitment of RAD51 to damaged DNA, impeded the homologous recombination-mediated DNA repair, and increased sensitivity of cells to radiation in vitro and in vivo, revealing an unexpected function of a core cell cycle protein in DNA repair.

TL;DR: DNA methylation marks that modify gene expression in IPF lung are identified and suggest that DNA methylation may be involved in the pathogenesis of IPF.

TL;DR: A significant decrease in overall diversity in the oral microbiome of pediatric CD is found, considering the proposed microbe–host interaction in IBD, the ease of visualization and direct oral mucosal sampling of the oral cavity is of potential diagnostic and prognostic value.

TL;DR: GeneSigDB provides a standardized resource of published prognostic, diagnostic and other gene signatures of cancer and related disease to the community so they can compare the predictive power of gene signatures or use these in gene set enrichment analysis.