M
Miia Kivipelto
Researcher at Karolinska University Hospital
Publications - 516
Citations - 70761
Miia Kivipelto is an academic researcher from Karolinska University Hospital. The author has contributed to research in topics: Dementia & Population. The author has an hindex of 91, co-authored 447 publications receiving 58328 citations. Previous affiliations of Miia Kivipelto include National Institute for Health and Welfare & National Institutes of Health.
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Journal ArticleDOI
Association of Vitamin B12, Folate, and Sulfur Amino Acids With Brain Magnetic Resonance Imaging Measures in Older Adults: A Longitudinal Population-Based Study
Babak Hooshmand,Babak Hooshmand,Francesca Mangialasche,Grégoria Kalpouzos,Alina Solomon,Ingemar Kåreholt,Ingemar Kåreholt,A. David Smith,Helga Refsum,Helga Refsum,Rui Wang,Marc Mühlmann,Birgit Ertl-Wagner,Erika J. Laukka,Lars Bäckman,Laura Fratiglioni,Miia Kivipelto +16 more
TL;DR: This study suggests that both vitamin B12 and total homocysteine concentrations may be related to accelerated aging of the brain and Randomized clinical trials are needed to determine the importance of vitamin B 12 supplementation on slowing brain aging in older adults.
Journal ArticleDOI
Classification and prediction of clinical diagnosis of Alzheimer's disease based on MRI and plasma measures of α-/γ-tocotrienols and γ-tocopherol.
Francesca Mangialasche,Francesca Mangialasche,Eric Westman,Eric Westman,Miia Kivipelto,Miia Kivipelto,J-Sebastian Muehlboeck,Roberta Cecchetti,Mauro Baglioni,Roberto Tarducci,G. Gobbi,Piero Floridi,H. Soininen,Iwona Kłoszewska,Magdalini Tsolaki,Bruno Vellas,Christian Spenger,Simon Lovestone,Simon Lovestone,L-O Wahlund,Andrew Simmons,Andrew Simmons,Patrizia Mecocci +22 more
TL;DR: Evaluated the accuracy of combined structural magnetic resonance imaging measures and plasma levels of vitamin E forms, including all eight natural vitamin E congeners, in differentiating individuals with Alzheimer's disease and mild cognitive impairment (MCI) from cognitively intact control (CTL) subjects.
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European Prevention of Alzheimer’s Dementia Longitudinal Cohort Study (EPAD LCS): study protocol
TL;DR: This characterisation of cognitive, biomarker and risk factor (genetic and environmental) status of research participants over time will provide the necessary well-phenotyped population for developing accurate longitudinal models for Alzheimer's disease covering the entire disease course and concurrently create a pool of highly characterised individuals for the EPAD PoC trial.
The road ahead to cure Alzheimer’s disease: development of biological markers and neuroimaging methods for prevention trials across all stages and target populations
Enrica Cavedo,Simone Lista,Zaven S. Khachaturian,Paul S. Aisen,Philippe Amouyel,Karl Herholz,C. R. Jack,Reisa A. Sperling,J. Cummings,Kaj Blennow,Sid E. O'Bryant,Giovanni B. Frisoni,Ara S. Khachaturian,Miia Kivipelto,William E. Klunk,Karl Broich,Sandrine Andrieu,M. Thiebaut de Schotten,Jean-François Mangin,Adriaan A. Lammertsma,Keith A. Johnson,Stefan J. Teipel,Alexander Drzezga,Arun L.W. Bokde,Olivier Colliot,Hovagim Bakardjian,Henrik Zetterberg,Bruno Dubois,Bruno Vellas,Lon S. Schneider,Harald Hampel +30 more
TL;DR: Six AD biomarkers are sufficiently validated and partly qualified to be incorporated into operationalized clinical diagnostic criteria and use in primary and secondary prevention trials, and novel promising hypothesis-driven and exploratory biochemical, genetic, electrophysiological, and neuroimaging markers for use in clinical trials are being developed.
Journal ArticleDOI
Healthy Ageing Through Internet Counselling in the Elderly: the HATICE randomised controlled trial for the prevention of cardiovascular disease and cognitive impairment.
Edo Richard,Susan Jongstra,Hilkka Soininen,Carol Brayne,Eric P. Moll van Charante,Yannick Meiller,Bram van der Groep,Cathrien Beishuizen,Francesca Mangialasche,Mariagnese Barbera,Tiia Ngandu,Nicola Coley,Juliette Guillemont,Stéphanie Savy,Marcel G. W. Dijkgraaf,Ron J.G. Peters,Willem A. van Gool,Miia Kivipelto,Sandrine Andrieu +18 more
TL;DR: In this article, the authors investigated whether a multidomain intervention to optimise self-management of cardiovascular risk factors in older individuals, delivered through an coach-supported interactive internet platform, can improve the cardiovascular risk profile and reduce the risk of cardiovascular disease and cognitive decline.