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Nadia K. Magdalinou

Researcher at UCL Institute of Neurology

Publications -  28
Citations -  2142

Nadia K. Magdalinou is an academic researcher from UCL Institute of Neurology. The author has contributed to research in topics: Progressive supranuclear palsy & Frontotemporal dementia. The author has an hindex of 17, co-authored 27 publications receiving 1574 citations. Previous affiliations of Nadia K. Magdalinou include University College London & University of London.

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Diagnostic Value of Cerebrospinal Fluid Neurofilament Light Protein in Neurology: A Systematic Review and Meta-analysis

Claire Bridel, +82 more
- 01 Sep 2019 - 
TL;DR: The cNfL increased with age in HC and a majority of neurological conditions, although the association was strongest in HC, and has potential to assist the differentiation of FTD from AD and PD from atypical parkinsonian syndromes.
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Blood-based NfL : A biomarker for differential diagnosis of parkinsonian disorder

TL;DR: In this paper, the authors determined if blood neurofilament light chain (NfL) protein can discriminate between Parkinson disease and atypical parkinsonian disorders with equally high diagnostic accuracies.
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Increased cerebrospinal fluid soluble TREM2 concentration in Alzheimer’s disease

TL;DR: A mass spectrometry method using selected reaction monitoring for the presence of a TREM2 peptide is developed, which can be used to quantify levels of sTREM2 in CSF, and correlate with markers of neurodegeneration.
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A panel of nine cerebrospinal fluid biomarkers may identify patients with atypical parkinsonian syndromes

TL;DR: A panel of nine CSF biomarkers was able to differentiate patients with PD from APS with an area under the curve of 0.95 and subtypes of APS from one another, and may have important clinical utility in improving diagnostic accuracy.
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Increased CSF neurogranin concentration is specific to Alzheimer disease.

TL;DR: These results confirm an increase in CSF Ng concentration in patients with AD as previously reported and show that this is specific to AD and not seen in a range of other neurodegenerative diseases.